# | Title | Journal | Year | Citations |
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|
1 | Increased Survival in Pancreatic Cancer with nab-Paclitaxel plus Gemcitabine | New England Journal of Medicine | 2013 | 5,314 |
2 | Erlotinib in Previously Treated Non–Small-Cell Lung Cancer | New England Journal of Medicine | 2005 | 5,289 |
3 | Docetaxel plus Prednisone or Mitoxantrone plus Prednisone for Advanced Prostate Cancer | New England Journal of Medicine | 2004 | 5,207 |
4 | Erlotinib Plus Gemcitabine Compared With Gemcitabine Alone in Patients With Advanced Pancreatic Cancer: A Phase III Trial of the National Cancer Institute of Canada Clinical Trials Group | Journal of Clinical Oncology | 2007 | 3,443 |
5 | The landscape of somatic copy-number alteration across human cancers | Nature | 2010 | 3,428 |
6 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,158 |
7 | Drug penetration in solid tumours | Nature Reviews Cancer | 2006 | 2,401 |
8 | Randomized Phase III Trial of Pemetrexed Versus Docetaxel in Patients With Non–Small-Cell Lung Cancer Previously Treated With Chemotherapy | Journal of Clinical Oncology | 2004 | 2,345 |
9 | Lung Adjuvant Cisplatin Evaluation: A Pooled Analysis by the LACE Collaborative Group | Journal of Clinical Oncology | 2008 | 2,197 |
10 | Gemcitabine and Cisplatin Versus Methotrexate, Vinblastine, Doxorubicin, and Cisplatin in Advanced or Metastatic Bladder Cancer: Results of a Large, Randomized, Multinational, Multicenter, Phase III Study | Journal of Clinical Oncology | 2000 | 2,006 |
11 | Drug Resistance and the Solid Tumor Microenvironment | Journal of the National Cancer Institute | 2007 | 1,838 |
12 | A Randomized Trial of Letrozole in Postmenopausal Women after Five Years of Tamoxifen Therapy for Early-Stage Breast Cancer | New England Journal of Medicine | 2003 | 1,729 |
13 | Long-Term Survival Results of a Randomized Trial Comparing Gemcitabine Plus Cisplatin, With Methotrexate, Vinblastine, Doxorubicin, Plus Cisplatin in Patients With Bladder Cancer | Journal of Clinical Oncology | 2005 | 1,626 |
14 | Preoperative versus postoperative radiotherapy in soft-tissue sarcoma of the limbs: a randomised trial | Lancet, The | 2002 | 1,377 |
15 | Monitoring CML patients responding to treatment with tyrosine kinase inhibitors: review and recommendations for harmonizing current methodology for detecting BCR-ABL transcripts and kinase domain mutations and for expressing results | Blood | 2006 | 1,121 |
16 | Hypoxia, DNA repair and genetic instability | Nature Reviews Cancer | 2008 | 1,012 |
17 | Hyperfractionated or accelerated radiotherapy in head and neck cancer: a meta-analysis | Lancet, The | 2006 | 977 |
18 | Estrogen and the Risk of Breast Cancer | New England Journal of Medicine | 2001 | 932 |
19 | External irradiation with or without long-term androgen suppression for prostate cancer with high metastatic risk: 10-year results of an EORTC randomised study | Lancet Oncology, The | 2010 | 844 |
20 | Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition) | European Journal of Immunology | 2019 | 816 |
21 | Metformin and Cancer Risk in Diabetic Patients: A Systematic Review and Meta-analysis | Cancer Prevention Research | 2010 | 800 |
22 | Multicenter Phase II Study of Erlotinib, an Oral Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor, in Patients With Recurrent or Metastatic Squamous Cell Cancer of the Head and Neck | Journal of Clinical Oncology | 2004 | 759 |
23 | Caspase 3–mediated stimulation of tumor cell repopulation during cancer radiotherapy | Nature Medicine | 2011 | 728 |
24 | Dose Escalation Methods in Phase I Cancer Clinical Trials | Journal of the National Cancer Institute | 2009 | 714 |
25 | Advanced pancreatic carcinoma: current treatment and future challenges | Nature Reviews Clinical Oncology | 2010 | 712 |
26 | Critical Impact of Radiotherapy Protocol Compliance and Quality in the Treatment of Advanced Head and Neck Cancer: Results From TROG 02.02 | Journal of Clinical Oncology | 2010 | 698 |
27 | EGFR Mutations and Lung Cancer | Annual Review of Pathology: Mechanisms of Disease | 2011 | 686 |
28 | Role of KRAS and EGFR As Biomarkers of Response to Erlotinib in National Cancer Institute of Canada Clinical Trials Group Study BR.21 | Journal of Clinical Oncology | 2008 | 676 |
29 | Delineation of the neck node levels for head and neck tumors: A 2013 update. DAHANCA, EORTC, HKNPCSG, NCIC CTG, NCRI, RTOG, TROG consensus guidelines | Radiotherapy and Oncology | 2014 | 624 |
30 | Repopulation of cancer cells during therapy: an important cause of treatment failure | Nature Reviews Cancer | 2005 | 613 |
31 | Tamoxifen with or without Breast Irradiation in Women 50 Years of Age or Older with Early Breast Cancer | New England Journal of Medicine | 2004 | 605 |
32 | Overall survival with cisplatin–gemcitabine and bevacizumab or placebo as first-line therapy for nonsquamous non-small-cell lung cancer: results from a randomised phase III trial (AVAiL) | Annals of Oncology | 2010 | 588 |
33 | Oxygenation predicts radiation response and survival in patients with cervix cancer | Radiotherapy and Oncology | 1998 | 570 |
34 | Cytokines and their relationship to the symptoms and outcome of cancer | Nature Reviews Cancer | 2008 | 561 |
35 | Toxicity of Adjuvant Endocrine Therapy in Postmenopausal Breast Cancer Patients: A Systematic Review and Meta-analysis | Journal of the National Cancer Institute | 2011 | 549 |
36 | Phase I Study of Individualized Stereotactic Body Radiotherapy for Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma | Journal of Clinical Oncology | 2008 | 546 |
37 | Prognostic Factors for Relapse in Stage I Seminoma Managed by Surveillance: A Pooled Analysis | Journal of Clinical Oncology | 2002 | 543 |
38 | Meta-analysis of dose-fractionation radiotherapy trials for the palliation of painful bone metastases | International Journal of Radiation Oncology Biology Physics | 2003 | 543 |
39 | Systematic Review of Barriers to the Recruitment of Older Patients With Cancer Onto Clinical Trials | Journal of Clinical Oncology | 2005 | 536 |
40 | Neurocognitive Function and Progression in Patients With Brain Metastases Treated With Whole-Brain Radiation and Motexafin Gadolinium: Results of a Randomized Phase III Trial | Journal of Clinical Oncology | 2004 | 529 |
41 | Second Malignant Neoplasms Among Long-Term Survivors of Hodgkin’s Disease: A Population-Based Evaluation Over 25 Years | Journal of Clinical Oncology | 2002 | 524 |
42 | Combined T2-Weighted and Diffusion-Weighted MRI for Localization of Prostate Cancer | American Journal of Roentgenology | 2007 | 520 |
43 | Guidelines for the use of flow cytometry and cell sorting in immunological studies* | European Journal of Immunology | 2017 | 520 |
44 | Cognitive Function in Breast Cancer Patients Receiving Adjuvant Chemotherapy | Journal of Clinical Oncology | 2000 | 514 |
45 | The International Association for the Study of Lung Cancer Lung Cancer Staging Project: Proposals Regarding the Clinical Staging of Small Cell Lung Cancer in the Forthcoming (Seventh) Edition of the Tumor, Node, Metastasis Classification for Lung Cancer | Journal of Thoracic Oncology | 2007 | 508 |
46 | Molecular Predictors of Outcome With Gefitinib and Docetaxel in Previously Treated Non–Small-Cell Lung Cancer: Data From the Randomized Phase III INTEREST Trial | Journal of Clinical Oncology | 2010 | 490 |
47 | The natural history of incidentally detected small renal masses | Cancer | 2004 | 486 |
48 | DNA Mismatch Repair Status and Colon Cancer Recurrence and Survival in Clinical Trials of 5-Fluorouracil-Based Adjuvant Therapy | Journal of the National Cancer Institute | 2011 | 479 |
49 | Influence of Androgen Suppression Therapy for Prostate Cancer on the Frequency and Timing of Fatal Myocardial Infarctions | Journal of Clinical Oncology | 2007 | 478 |
50 | International Spine Radiosurgery Consortium Consensus Guidelines for Target Volume Definition in Spinal Stereotactic Radiosurgery | International Journal of Radiation Oncology Biology Physics | 2012 | 477 |