| # | Title | Journal | Year | Citations |
|---|
|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,789 |
| 2 | Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease | Cell | 2017 | 4,514 |
| 3 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,158 |
| 4 | An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics | Cell | 2018 | 2,498 |
| 5 | Comparison of the Mechanism of Toxicity of Zinc Oxide and Cerium Oxide Nanoparticles Based on Dissolution and Oxidative Stress Properties | ACS Nano | 2008 | 2,189 |
| 6 | Updated Clinical Classification of Pulmonary Hypertension | Journal of the American College of Cardiology | 2009 | 1,930 |
| 7 | Signals for Sorting of Transmembrane Proteins to Endosomes and Lysosomes | Annual Review of Biochemistry | 2003 | 1,878 |
| 8 | Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis | Nature Chemical Biology | 2017 | 1,783 |
| 9 | Cleft lip and palate: understanding genetic and environmental influences | Nature Reviews Genetics | 2011 | 1,496 |
| 10 | Guidelines and definitions for research on epithelial–mesenchymal transition | Nature Reviews Molecular Cell Biology | 2020 | 1,324 |
| 11 | The KEAP1-NRF2 System: a Thiol-Based Sensor-Effector Apparatus for Maintaining Redox Homeostasis | Physiological Reviews | 2018 | 1,201 |
| 12 | Rescue of CF airway epithelial cell function in vitro by a CFTR potentiator, VX-770 | Proceedings of the National Academy of Sciences of the United States of America | 2009 | 1,085 |
| 13 | Correction of the F508del-CFTR protein processing defect in vitro by the investigational drug VX-809 | Proceedings of the National Academy of Sciences of the United States of America | 2011 | 979 |
| 14 | Skeletal Muscle Lipid Content and Insulin Resistance: Evidence for a Paradox in Endurance-Trained Athletes | Journal of Clinical Endocrinology and Metabolism | 2001 | 954 |
| 15 | ProDy: Protein Dynamics Inferred from Theory and Experiments | Bioinformatics | 2011 | 953 |
| 16 | KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis | Nature Medicine | 2015 | 927 |
| 17 | Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis | Journal of Experimental Medicine | 2009 | 894 |
| 18 | MicroRNA Expression Signature and Antisense-Mediated Depletion Reveal an Essential Role of MicroRNA in Vascular Neointimal Lesion Formation | Circulation Research | 2007 | 859 |
| 19 | Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells | Nature Cell Biology | 2013 | 835 |
| 20 | DNA–based immunization by in vivo transfection of dendritic cells | Nature Medicine | 1996 | 817 |
| 21 | Increased hypothalamic GPR54 signaling: A potential mechanism for initiation of puberty in primates | Proceedings of the National Academy of Sciences of the United States of America | 2005 | 791 |
| 22 | Molecular Characterization of Neuroendocrine Prostate Cancer and Identification of New Drug Targets | Cancer Discovery | 2011 | 762 |
| 23 | Interleukin‐17 and its target genes: mechanisms of interleukin‐17 function in disease | Immunology | 2010 | 758 |
| 24 | Lessons Learned in Empirical Scoring with smina from the CSAR 2011 Benchmarking Exercise | Journal of Chemical Information and Modeling | 2013 | 749 |
| 25 | Multidimensional free-energy calculations using the weighted histogram analysis method | Journal of Computational Chemistry | 1995 | 743 |
| 26 | Mesenchymal stem cells use extracellular vesicles to outsource mitophagy and shuttle microRNAs | Nature Communications | 2015 | 742 |
| 27 | Mature HIV-1 capsid structure by cryo-electron microscopy and all-atom molecular dynamics | Nature | 2013 | 738 |
| 28 | Stem Cell Characteristics of Amniotic Epithelial Cells | Stem Cells | 2005 | 727 |
| 29 | Identification of ACSL4 as a biomarker and contributor of ferroptosis | Biochemical and Biophysical Research Communications | 2016 | 719 |
| 30 | Carbon nanotubes degraded by neutrophil myeloperoxidase induce less pulmonary inflammation | Nature Nanotechnology | 2010 | 705 |
| 31 | Coarse-grained normal mode analysis in structural biology | Current Opinion in Structural Biology | 2005 | 683 |
| 32 | Comparison of the Respiratory Microbiome in Healthy Nonsmokers and Smokers | American Journal of Respiratory and Critical Care Medicine | 2013 | 676 |
| 33 | Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences | Nature | 2007 | 669 |
| 34 | Contribution of rare inherited and de novo variants in 2,871 congenital heart disease probands | Nature Genetics | 2017 | 667 |
| 35 | How many human proteoforms are there? | Nature Chemical Biology | 2018 | 666 |
| 36 | The Tumor Suppressor p53 Limits Ferroptosis by Blocking DPP4 Activity | Cell Reports | 2017 | 665 |
| 37 | PEBP1 Wardens Ferroptosis by Enabling Lipoxygenase Generation of Lipid Death Signals | Cell | 2017 | 654 |
| 38 | Altered urinary bladder function in mice lacking the vanilloid receptor TRPV1 | Nature Neuroscience | 2002 | 648 |
| 39 | Hypoxia promotes expansion of the CD133-positive glioma stem cells through activation of HIF-1α | Oncogene | 2009 | 639 |
| 40 | Neutrophil elastase–mediated degradation of IRS-1 accelerates lung tumor growth | Nature Medicine | 2010 | 637 |
| 41 | Linking of Autophagy to Ubiquitin-Proteasome System Is Important for the Regulation of Endoplasmic Reticulum Stress and Cell Viability | American Journal of Pathology | 2007 | 630 |
| 42 | Microporous Metal Organic Materials: Promising Candidates as Sorbents for Hydrogen Storage | Journal of the American Chemical Society | 2004 | 622 |
| 43 | Mitochondrial electron transport chain: Oxidative phosphorylation, oxidant production, and methods of measurement | Redox Biology | 2020 | 619 |
| 44 | Metabolic support of tumour-infiltrating regulatory T cells by lactic acid | Nature | 2021 | 605 |
| 45 | Energy Metabolism in Human Pluripotent Stem Cells and Their Differentiated Counterparts | PLoS ONE | 2011 | 585 |
| 46 | HMGB1 release induced by liver ischemia involves Toll-like receptor 4–dependent reactive oxygen species production and calcium-mediated signaling | Journal of Experimental Medicine | 2007 | 564 |
| 47 | The Tumor Microenvironment Represses T Cell Mitochondrial Biogenesis to Drive Intratumoral T Cell Metabolic Insufficiency and Dysfunction | Immunity | 2016 | 547 |
| 48 | When NRF2 Talks, Who's Listening? | Antioxidants and Redox Signaling | 2010 | 546 |
| 49 | Global Dynamics of Proteins: Bridging Between Structure and Function | Annual Review of Biophysics | 2010 | 545 |
| 50 | A model for gene therapy of human hereditary lymphedema | Proceedings of the National Academy of Sciences of the United States of America | 2001 | 544 |
