# | Title | Journal | Year | Citations |
---|
|
1 | Amplification of a gene encoding a p53-associated protein in human sarcomas | Nature | 1992 | 1,942 |
2 | Gene-expression profiles predict survival of patients with lung adenocarcinoma | Nature Medicine | 2002 | 1,800 |
3 | Child development: risk factors for adverse outcomes in developing countries | Lancet, The | 2007 | 1,623 |
4 | Conjoint Analysis Applications in Health—a Checklist: A Report of the ISPOR Good Research Practices for Conjoint Analysis Task Force | Value in Health | 2011 | 1,429 |
5 | Inequality in early childhood: risk and protective factors for early child development | Lancet, The | 2011 | 1,286 |
6 | Insights into Autism Spectrum Disorder Genomic Architecture and Biology from 71 Risk Loci | Neuron | 2015 | 1,264 |
7 | Multiple Recurrent De Novo CNVs, Including Duplications of the 7q11.23 Williams Syndrome Region, Are Strongly Associated with Autism | Neuron | 2011 | 1,163 |
8 | WFH Guidelines for the Management of Hemophilia, 3rd edition | Haemophilia | 2020 | 1,074 |
9 | Urinary, Circulating, and Tissue Biomonitoring Studies Indicate Widespread Exposure to Bisphenol A | Environmental Health Perspectives | 2010 | 1,059 |
10 | Effective Messages in Vaccine Promotion: A Randomized Trial | Pediatrics | 2014 | 973 |
11 | Disease proteomics | Nature | 2003 | 968 |
12 | Discordant Protein and mRNA Expression in Lung Adenocarcinomas | Molecular and Cellular Proteomics | 2002 | 821 |
13 | Integrative clinical genomics of metastatic cancer | Nature | 2017 | 729 |
14 | Toxicity and management in CAR T-cell therapy | Molecular Therapy - Oncolytics | 2016 | 717 |
15 | Isolation of a partial candidate gene for Menkes disease by positional cloning | Nature Genetics | 1993 | 692 |
16 | The primacy of the gastrointestinal tract as a target organ of acute graft-versus-host disease: rationale for the use of cytokine shields in allogeneic bone marrow transplantation | Blood | 2000 | 646 |
17 | Extracorporeal Circulation in Neonatal Respiratory Failure: A Prospective Randomized Study | Pediatrics | 1985 | 634 |
18 | The Simons Simplex Collection: A Resource for Identification of Autism Genetic Risk Factors | Neuron | 2010 | 625 |
19 | Membrane Type I Matrix Metalloproteinase Usurps Tumor Growth Control Imposed by the Three-Dimensional Extracellular Matrix | Cell | 2003 | 617 |
20 | Biobank-driven genomic discovery yields new insight into atrial fibrillation biology | Nature Genetics | 2018 | 612 |
21 | The Effect of Weight Loss on the Sensitivity of Blood Pressure to Sodium in Obese Adolescents | New England Journal of Medicine | 1989 | 596 |
22 | Connexin 43 (GJA1) Mutations Cause the Pleiotropic Phenotype of Oculodentodigital Dysplasia | American Journal of Human Genetics | 2003 | 593 |
23 | Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination | Nature Genetics | 2003 | 587 |
24 | A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition | Nature Genetics | 2011 | 568 |
25 | Association of Hospital-Level Volume of Extracorporeal Membrane Oxygenation Cases and Mortality. Analysis of the Extracorporeal Life Support Organization Registry | American Journal of Respiratory and Critical Care Medicine | 2015 | 565 |
26 | EGFR, p16, HPV Titer, Bcl-xL and p53, Sex, and Smoking As Indicators of Response to Therapy and Survival in Oropharyngeal Cancer | Journal of Clinical Oncology | 2008 | 563 |
27 | Psychological Status in Childhood Cancer Survivors: A Report From the Childhood Cancer Survivor Study | Journal of Clinical Oncology | 2009 | 559 |
28 | Mutations in FOXC2 (MFH-1), a Forkhead Family Transcription Factor, Are Responsible for the Hereditary Lymphedema-Distichiasis Syndrome | American Journal of Human Genetics | 2000 | 554 |
29 | Iron Deficiency and Brain Development | Seminars in Pediatric Neurology | 2006 | 552 |
30 | Mapping the NPHP-JBTS-MKS Protein Network Reveals Ciliopathy Disease Genes and Pathways | Cell | 2011 | 543 |
31 | An excitatory paraventricular nucleus to AgRP neuron circuit that drives hunger | Nature | 2014 | 542 |
32 | Evidence for impaired t cell dna methylation in systemic lupus erythematosus and rheumatoid arthritis | Arthritis and Rheumatism | 1990 | 541 |
33 | Recurrent reciprocal 1q21.1 deletions and duplications associated with microcephaly or macrocephaly and developmental and behavioral abnormalities | Nature Genetics | 2008 | 540 |
34 | The centrosomal protein nephrocystin-6 is mutated in Joubert syndrome and activates transcription factor ATF4 | Nature Genetics | 2006 | 537 |
35 | Personalized Oncology Through Integrative High-Throughput Sequencing: A Pilot Study | Science Translational Medicine | 2011 | 533 |
36 | Detectable clonal mosaicism from birth to old age and its relationship to cancer | Nature Genetics | 2012 | 525 |
37 | A Single-Gene Cause in 29.5% of Cases of Steroid-Resistant Nephrotic Syndrome | Journal of the American Society of Nephrology: JASN | 2015 | 519 |
38 | Positional cloning uncovers mutations in PLCE1 responsible for a nephrotic syndrome variant that may be reversible | Nature Genetics | 2006 | 517 |
39 | Acute graft-versus-host disease does not require alloantigen expression on host epithelium | Nature Medicine | 2002 | 499 |
40 | American College of Critical Care Medicine Clinical Practice Parameters for Hemodynamic Support of Pediatric and Neonatal Septic Shock | Critical Care Medicine | 2017 | 497 |
41 | Late mortality after allogeneic hematopoietic cell transplantation and functional status of long-term survivors: report from the Bone Marrow Transplant Survivor Study | Blood | 2007 | 496 |
42 | Inattention, Hyperactivity, and Symptoms of Sleep-Disordered Breathing | Pediatrics | 2002 | 477 |
43 | Mutation of HOXA13 in hand-foot-genital syndrome | Nature Genetics | 1997 | 475 |
44 | Global Profiling of the Cell Surface Proteome of Cancer Cells Uncovers an Abundance of Proteins with Chaperone Function | Journal of Biological Chemistry | 2003 | 471 |
45 | Notch signaling modulates proliferation and differentiation of intestinal crypt base columnar stem cells | Development (Cambridge) | 2012 | 459 |
46 | Epidemiology of Depressive Symptoms in the National Longitudinal Study of Adolescent Health | Journal of the American Academy of Child and Adolescent Psychiatry | 2002 | 457 |
47 | Bisphenol A and Reproductive Health: Update of Experimental and Human Evidence, 2007–2013 | Environmental Health Perspectives | 2014 | 453 |
48 | A de novo Alu insertion results in neurofibromatosis type 1 | Nature | 1991 | 451 |
49 | The ciliary gene RPGRIP1L is mutated in cerebello-oculo-renal syndrome (Joubert syndrome type B) and Meckel syndrome | Nature Genetics | 2007 | 446 |
50 | Mutations in NALP7 cause recurrent hydatidiform moles and reproductive wastage in humans | Nature Genetics | 2006 | 429 |