| Detection of circulating tumor DNA in early- and late-stage human malignancies | Science Translational Medicine | 2014 | 2.7K |
| DNMT1 and DNMT3b cooperate to silence genes in human cancer cells | Nature | 2002 | 1K |
| The vigorous immune microenvironment of microsatellite instable colon cancer is balanced by multiple counter-inhibitory checkpoints | Cancer Discovery | 2015 | 890 |
| A protocol for rapid generation of recombinant adenoviruses using the AdEasy system | Nature Protocols | 2007 | 645 |
| Eradication of metastatic mouse cancers resistant to immune checkpoint blockade by suppression of myeloid-derived cells | Proceedings of the National Academy of Sciences of the United States of America | 2014 | 426 |
| Hedgehog signaling maintains a tumor stem cell compartment in multiple myeloma | Proceedings of the National Academy of Sciences of the United States of America | 2007 | 405 |
| Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma | Nature Genetics | 2013 | 300 |
| Comparing the DNA hypermethylome with gene mutations in human colorectal cancer | PLoS Genetics | 2007 | 272 |
| Detection of APC mutations in fecal DNA from patients with colorectal tumors | New England Journal of Medicine | 2002 | 267 |
| Detection of somatic mutations and HPV in the saliva and plasma of patients with head and neck squamous cell carcinomas | Science Translational Medicine | 2015 | 265 |
| DNA methylation regulates MicroRNA expression | Cancer Biology and Therapy | 2007 | 250 |
| Shaggy/GSK3 antagonizes Hedgehog signalling by regulating Cubitus interruptus | Nature | 2002 | 249 |
| Intratumoral injection of Clostridium novyi-NT spores induces antitumor responses | Science Translational Medicine | 2014 | 202 |
| Tumour-targeting bacteria engineered to fight cancer | Nature Reviews Cancer | 2018 | 196 |
| Role of NADPH oxidase in arsenic-induced reactive oxygen species formation and cytotoxicity in myeloid leukemia cells | Proceedings of the National Academy of Sciences of the United States of America | 2004 | 192 |
| TEM8 interacts with the cleaved C5 domain of collagen alpha 3(VI) | Cancer Research | 2004 | 152 |
| Circulating tumor DNA analysis as a real-time method for monitoring tumor burden in melanoma patients undergoing treatment with immune checkpoint blockade | | 2014 | 148 |
| Serial assessment of human tumor burdens in mice by the analysis of circulating DNA | Cancer Research | 2007 | 124 |
| Genomic analyses of gynaecologic carcinosarcomas reveal frequent mutations in chromatin remodelling genes | Nature Communications | 2014 | 120 |
| Systemic use of tumor necrosis factor alpha as an anticancer agent | Oncotarget | 2011 | 120 |
| Evaluation of liquid from the Papanicolaou test and other liquid biopsies for the detection of endometrial and ovarian cancers | Science Translational Medicine | 2018 | 110 |
| The role of companion diagnostics in the development and use of mutation-targeted cancer therapies | Nature Biotechnology | 2006 | 108 |
| Tumor endothelial markers: new targets for cancer therapy | Current Opinion in Oncology | 2004 | 108 |
| The genome and transcriptomes of the anti-tumor agent Clostridium novyi-NT | Nature Biotechnology | 2006 | 105 |
| Genetic knockouts and knockins in human somatic cells | Nature Protocols | 2007 | 97 |
