Detection of circulating tumor DNA in early- and late-stage human malignancies | Science Translational Medicine | 2014 | 2.7K |
Survival, durable tumor remission, and long-term safety in patients with advanced melanoma receiving nivolumab | Journal of Clinical Oncology | 2014 | 1.7K |
Association of PD-1, PD-1 ligands, and other features of the tumor immune microenvironment with response to anti-PD-1 therapy | Clinical Cancer Research | 2014 | 1.7K |
A draft map of the human proteome | Nature | 2014 | 1.5K |
Hypoxia and the extracellular matrix: drivers of tumour metastasis | Nature Reviews Cancer | 2014 | 785 |
Blood-based analyses of cancer: circulating tumor cells and circulating tumor DNA | Cancer Discovery | 2014 | 473 |
Association between class III obesity (BMI of 40-59 kg/m2) and mortality: a pooled analysis of 20 prospective studies | PLoS Medicine | 2014 | 208 |
Intratumoral injection of Clostridium novyi-NT spores induces antitumor responses | Science Translational Medicine | 2014 | 202 |
Bacteroides fragilis subverts mucosal biology: from symbiont to colon carcinogenesis | Journal of Clinical Investigation | 2014 | 173 |
A targeting modality for destruction of RNA polymerase I that possesses anticancer activity | Cancer Cell | 2014 | 160 |
Chronic inflammation in benign prostate tissue is associated with high-grade prostate cancer in the placebo arm of the prostate cancer prevention trial | Cancer Epidemiology Biomarkers and Prevention | 2014 | 160 |
A temporal requirement for Hippo signaling in mammary gland differentiation, growth, and tumorigenesis | Genes and Development | 2014 | 149 |
Circulating tumor DNA analysis as a real-time method for monitoring tumor burden in melanoma patients undergoing treatment with immune checkpoint blockade | | 2014 | 148 |
Twist1-induced dissemination preserves epithelial identity and requires E-cadherin | Journal of Cell Biology | 2014 | 145 |
Proto-oncogenic role of mutant IDH2 in leukemia initiation and maintenance | Cell Stem Cell | 2014 | 141 |
Ibrutinib treatment ameliorates murine chronic graft-versus-host disease | Journal of Clinical Investigation | 2014 | 132 |
A single institution's 26-year experience with nonfunctional pancreatic neuroendocrine tumors: a validation of current staging systems and a new prognostic nomogram | Annals of Surgery | 2014 | 129 |
The growth of palliative care in the United States | Annual Review of Public Health | 2014 | 126 |
Genomic analyses of gynaecologic carcinosarcomas reveal frequent mutations in chromatin remodelling genes | Nature Communications | 2014 | 120 |
Treg functional stability and its responsiveness to the microenvironment | Immunological Reviews | 2014 | 119 |
Phase I dose-escalation study of AZD7762, a checkpoint kinase inhibitor, in combination with gemcitabine in US patients with advanced solid tumors | Cancer Chemotherapy and Pharmacology | 2014 | 115 |
Lung transplantation in telomerase mutation carriers with pulmonary fibrosis | European Respiratory Journal | 2014 | 113 |
Breast cancer cells condition lymphatic endothelial cells within pre-metastatic niches to promote metastasis | Nature Communications | 2014 | 108 |
Successful administration of ipilimumab to two kidney transplantation patients with metastatic melanoma | Journal of Clinical Oncology | 2014 | 108 |
Key tumor suppressor genes inactivated by "greater promoter" methylation and somatic mutations in head and neck cancer | Epigenetics | 2014 | 105 |