Cancer genes and the pathways they control | Nature Medicine | 2004 | 3.2K |
Histone demethylation mediated by the nuclear amine oxidase homolog LSD1 | Cell | 2004 | 3.1K |
High frequency of mutations of the PIK3CA gene in human cancers | Science | 2004 | 2.7K |
Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer | Nature Genetics | 2004 | 900 |
Role of LAG-3 in regulatory T cells | Immunity | 2004 | 842 |
Aneuploidy and cancer | Nature | 2004 | 558 |
Hematopoietic stem cells convert into liver cells within days without fusion | Nature Cell Biology | 2004 | 489 |
Inactivation of hCDC4 can cause chromosomal instability | Nature | 2004 | 464 |
Mutational analysis of the tyrosine phosphatome in colorectal cancers | Science | 2004 | 431 |
Human papillomavirus-associated head and neck cancer is a distinct epidemiologic, clinical, and molecular entity | Seminars in Oncology | 2004 | 420 |
Activating mutations of the noonan syndrome-associated SHP2/PTPN11 gene in human solid tumors and adult acute myelogenous leukemia | Cancer Research | 2004 | 404 |
Oncogenic mutations of PIK3CA in human cancers | Cell Cycle | 2004 | 384 |
Tumour suppression: disruption of HAUSP gene stabilizes p53 | Nature | 2004 | 265 |
The role of inflammation in the pathogenesis of prostate cancer | Journal of Urology | 2004 | 242 |
Tumor cell-specific BRCA1 and RASSF1A hypermethylation in serum, plasma, and peritoneal fluid from ovarian cancer patients | Cancer Research | 2004 | 225 |
Serum macrophage inhibitory cytokine 1 as a marker of pancreatic and other periampullary cancers | Clinical Cancer Research | 2004 | 221 |
Clostridium perfringens enterotoxin elicits rapid and specific cytolysis of breast carcinoma cells mediated through tight junction proteins claudin 3 and 4 | American Journal of Pathology | 2004 | 200 |
Role of NADPH oxidase in arsenic-induced reactive oxygen species formation and cytotoxicity in myeloid leukemia cells | Proceedings of the National Academy of Sciences of the United States of America | 2004 | 192 |
Plasma 1,25-dihydroxy- and 25-hydroxyvitamin D and subsequent risk of prostate cancer | Cancer Causes and Control | 2004 | 191 |
GSTP1 CpG island hypermethylation as a molecular biomarker for prostate cancer | Journal of Cellular Biochemistry | 2004 | 169 |
Alterations in vascular gene expression in invasive breast carcinoma | Cancer Research | 2004 | 165 |
Digital karyotyping identifies thymidylate synthase amplification as a mechanism of resistance to 5-fluorouracil in metastatic colorectal cancer patients | Proceedings of the National Academy of Sciences of the United States of America | 2004 | 163 |
Preliminary results of Radiation Therapy Oncology Group 97-03: a randomized phase ii trial of concurrent radiation and chemotherapy for advanced squamous cell carcinomas of the head and neck | Journal of Clinical Oncology | 2004 | 146 |
Epigenetic and genetic loss of Hic1 function accentuates the role of p53 in tumorigenesis | Cancer Cell | 2004 | 141 |
Spermine oxidation induced by Helicobacter pylori results in apoptosis and DNA damage: implications for gastric carcinogenesis | Cancer Research | 2004 | 138 |