The fundamental role of epigenetic events in cancer | Nature Reviews Genetics | 2002 | 4.3K |
DNMT1 and DNMT3b cooperate to silence genes in human cancer cells | Nature | 2002 | 1K |
Tumorigenesis: RAF/RAS oncogenes and mismatch-repair status | Nature | 2002 | 962 |
A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer | Nature Genetics | 2002 | 766 |
Allelic variation in human gene expression | Science | 2002 | 567 |
Using the transcriptome to annotate the genome | Nature Biotechnology | 2002 | 528 |
The role of chromosomal instability in tumor initiation | Proceedings of the National Academy of Sciences of the United States of America | 2002 | 399 |
Germline mutations and sequence variants of the macrophage scavenger receptor 1 gene are associated with prostate cancer risk | Nature Genetics | 2002 | 283 |
Shaggy/GSK3 antagonizes Hedgehog signalling by regulating Cubitus interruptus | Nature | 2002 | 249 |
Digital karyotyping | Proceedings of the National Academy of Sciences of the United States of America | 2002 | 191 |
Id1 regulates angiogenesis through transcriptional repression of thrombospondin-1 | Cancer Cell | 2002 | 170 |
Prevalence of somatic alterations in the colorectal cancer cell genome | Proceedings of the National Academy of Sciences of the United States of America | 2002 | 163 |
Counting alleles to predict recurrence of early-stage colorectal cancers | Lancet, The | 2002 | 127 |
Role and regulation of activator protein-1 in toxicant-induced responses of the lung | American Journal of Physiology - Lung Cellular and Molecular Physiology | 2002 | 118 |
DEC1 is a downstream target of TGF-beta with sequence-specific transcriptional repressor activities | Proceedings of the National Academy of Sciences of the United States of America | 2002 | 74 |
Human stem-progenitor cells from neonatal cord blood have greater hematopoietic expansion capacity than those from mobilized adult blood | Experimental Hematology | 2002 | 72 |
Human AML cells in NOD/SCID mice: engraftment potential and gene expression | Leukemia | 2002 | 52 |
Third-generation, self-inactivating gp91(phox) lentivector corrects the oxidase defect in NOD/SCID mouse-repopulating peripheral blood-mobilized CD34+ cells from patients with X-linked chronic granulomatous disease | Blood | 2002 | 52 |
Energy imbalance and prostate cancer | Journal of Nutrition | 2002 | 44 |
Transduction of donor hematopoietic stem-progenitor cells with Fas ligand enhanced short-term engraftment in a murine model of allogeneic bone marrow transplantation | Blood | 2002 | 34 |
Development of matrix metalloproteinase inhibitors in cancer therapy | Hematology/Oncology Clinics of North America | 2002 | 20 |
Exploring and exploiting instability | Cancer Biology and Therapy | 2002 | 12 |
Epstein-Barr virus DNA in body fluids | Current Opinion in Oncology | 2002 | 11 |
Potential methods to circumvent blocks in apoptosis in lymphomas | Current Opinion in Oncology | 2002 | 10 |
Pharmacological treatments for prostate cancer | Expert Opinion on Investigational Drugs | 2002 | 8 |