Mechanism and function of signal transduction by the Wnt/beta-catenin and Wnt/Ca2+ pathways | Oncogene | 1999 | 604 |
Making new connections: role of ERK/MAP kinase signaling in neuronal plasticity | Neuron | 1999 | 531 |
The mitogen-activated protein kinase pathway mediates estrogen neuroprotection after glutamate toxicity in primary cortical neurons | Journal of Neuroscience | 1999 | 511 |
Missense and silent tau gene mutations cause frontotemporal dementia with parkinsonism-chromosome 17 type, by affecting multiple alternative RNA splicing regulatory elements | Proceedings of the National Academy of Sciences of the United States of America | 1999 | 448 |
Ca2+/calmodulin binds to and modulates P/Q-type calcium channels | Nature | 1999 | 428 |
Prevention of glucose toxicity in HIT-T15 cells and Zucker diabetic fatty rats by antioxidants | Proceedings of the National Academy of Sciences of the United States of America | 1999 | 369 |
Calcium channel types with distinct presynaptic localization couple differentially to transmitter release in single calyx-type synapses | Journal of Neuroscience | 1999 | 364 |
Isolation and characterization of a dual-substrate phosphodiesterase gene family: PDE10A | Proceedings of the National Academy of Sciences of the United States of America | 1999 | 336 |
Abnormal neurotransmission in mice lacking synaptic vesicle protein 2A (SV2A) | Proceedings of the National Academy of Sciences of the United States of America | 1999 | 309 |
Circadian regulation of cAMP response element-mediated gene expression in the suprachiasmatic nuclei | Journal of Biological Chemistry | 1999 | 234 |
Interactions of presynaptic Ca2+ channels and snare proteins in neurotransmitter release | Annals of the New York Academy of Sciences | 1999 | 225 |
Distinct domains of the CB1 cannabinoid receptor mediate desensitization and internalization | Journal of Neuroscience | 1999 | 200 |
Targeted construction of phosphorylation-independent beta-arrestin mutants with constitutive activity in cells | Journal of Biological Chemistry | 1999 | 164 |
Mitogen-activated protein kinase kinase activity is required for the G(2)/M transition of the cell cycle in mammalian fibroblasts | Proceedings of the National Academy of Sciences of the United States of America | 1999 | 157 |
Serotonin 5-HT2C receptor RNA editing alters receptor basal activity: implications for serotonergic signal transduction | Journal of Neurochemistry | 1999 | 151 |
A distinct familial presenile dementia with a novel missense mutation in the tau gene | NeuroReport | 1999 | 140 |
Reciprocal regulation of P/Q-type Ca2+ channels by SNAP-25, syntaxin and synaptotagmin | Nature Neuroscience | 1999 | 138 |
Failure of erythromycin breath test to correlate with midazolam clearance as a probe of cytochrome P4503A | Clinical Pharmacology and Therapeutics | 1999 | 117 |
Solution structure of the sodium channel inactivation gate | Biochemistry | 1999 | 116 |
Estradiol inhibits leukocyte adhesion and transendothelial migration in rabbits in vivo : possible mechanisms for gender differences in atherosclerosis | Circulation Research | 1999 | 115 |
Enzymatic determinants of the substrate specificity of CYP2C9: role of B'-C loop residues in providing the pi-stacking anchor site for warfarin binding | Biochemistry | 1999 | 88 |
Structural forms of phenprocoumon and warfarin that are metabolized at the active site of CYP2C9 | Archives of Biochemistry and Biophysics | 1999 | 86 |
Voltage-dependent neuromodulation of Na+ channels by D1-like dopamine receptors in rat hippocampal neurons | Journal of Neuroscience | 1999 | 84 |
In vivo prevention of hyperglycemia also prevents glucotoxic effects on PDX-1 and insulin gene expression | Diabetes | 1999 | 78 |
Interactions between neurogranin and calmodulin in vivo | Journal of Biological Chemistry | 1999 | 77 |