# | Title | Journal | Year | Citations |
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1 | Toll-Like Receptor Triggering of a Vitamin D-Mediated Human Antimicrobial Response | Science | 2006 | 3,425 |
2 | Innate antimicrobial peptide protects the skin from invasive bacterial infection | Nature | 2001 | 1,420 |
3 | Activation by IKKα of a Second, Evolutionary Conserved, NF-κB Signaling Pathway | Science | 2001 | 1,286 |
4 | AMPed up immunity: how antimicrobial peptides have multiple roles in immune defense | Trends in Immunology | 2009 | 1,047 |
5 | Guidelines of care for the management of atopic dermatitis | Journal of the American Academy of Dermatology | 2014 | 1,015 |
6 | Epithelial antimicrobial defence of the skin and intestine | Nature Reviews Immunology | 2012 | 812 |
7 | Antimicrobials from human skin commensal bacteria protect against Staphylococcus aureus and are deficient in atopic dermatitis | Science Translational Medicine | 2017 | 802 |
8 | Skin microbiota: a source of disease or defence? | British Journal of Dermatology | 2008 | 767 |
9 | Increased serine protease activity and cathelicidin promotes skin inflammation in rosacea | Nature Medicine | 2007 | 723 |
10 | Commensal bacteria regulate Toll-like receptor 3–dependent inflammation after skin injury | Nature Medicine | 2009 | 644 |
11 | Tight junction defects in patients with atopic dermatitis | Journal of Allergy and Clinical Immunology | 2011 | 595 |
12 | Injury enhances TLR2 function and antimicrobial peptide expression through a vitamin D–dependent mechanism | Journal of Clinical Investigation | 2007 | 586 |
13 | Glycosaminoglycans and their proteoglycans: host‐associated molecular patterns for initiation and modulation of inflammation | FASEB Journal | 2006 | 566 |
14 | The antimicrobial peptide cathelicidin protects the urinary tract against invasive bacterial infection | Nature Medicine | 2006 | 557 |
15 | Cutaneous Injury Induces the Release of Cathelicidin Anti-Microbial Peptides Active Against Group A Streptococcus | Journal of Investigative Dermatology | 2001 | 498 |
16 | Hyaluronan Fragments Stimulate Endothelial Recognition of Injury through TLR4 | Journal of Biological Chemistry | 2004 | 476 |
17 | Mass Spectrometry-Based Label-Free Quantitative Proteomics | Journal of Biomedicine and Biotechnology | 2010 | 441 |
18 | Human Histology and Persistence of Various Injectable Filler Substances for Soft Tissue Augmentation | Aesthetic Plastic Surgery | 2003 | 432 |
19 | Multipotent nestin-positive, keratin-negative hair-follicle bulge stem cells can form neurons | Proceedings of the National Academy of Sciences of the United States of America | 2005 | 408 |
20 | Kallikrein‐mediated proteolysis regulates the antimicrobial effects of cathelicidins in skin | FASEB Journal | 2006 | 406 |
21 | Dermatan sulfate: new functions from an old glycosaminoglycan | Glycobiology | 2002 | 405 |
22 | Addendum guidelines for the prevention of peanut allergy in the United States: Report of the National Institute of Allergy and Infectious Diseases–sponsored expert panel | Journal of Allergy and Clinical Immunology | 2017 | 390 |
23 | The microbiome extends to subepidermal compartments of normal skin | Nature Communications | 2013 | 373 |
24 | Structure and function of the human skin microbiome | Trends in Microbiology | 2013 | 372 |
25 | Functions of the skin microbiota in health and disease | Seminars in Immunology | 2013 | 368 |
26 | Activation of TLR2 by a Small Molecule Produced by Staphylococcus epidermidis Increases Antimicrobial Defense against Bacterial Skin Infections | Journal of Investigative Dermatology | 2010 | 360 |
27 | Cytosolic DNA Triggers Inflammasome Activation in Keratinocytes in Psoriatic Lesions | Science Translational Medicine | 2011 | 354 |
28 | Recognition of Hyaluronan Released in Sterile Injury Involves a Unique Receptor Complex Dependent on Toll-like Receptor 4, CD44, and MD-2 | Journal of Biological Chemistry | 2007 | 350 |
29 | Ultraviolet radiation damages self noncoding RNA and is detected by TLR3 | Nature Medicine | 2012 | 346 |
30 | Selective Antimicrobial Action Is Provided by Phenol-Soluble Modulins Derived from Staphylococcus epidermidis, a Normal Resident of the Skin | Journal of Investigative Dermatology | 2010 | 344 |
31 | The microbiome in patients with atopic dermatitis | Journal of Allergy and Clinical Immunology | 2019 | 335 |
32 | The antimicrobial peptide LL-37 is expressed by keratinocytes in condyloma acuminatum and verruca vulgaris | Journal of the American Academy of Dermatology | 2002 | 331 |
33 | Cytokine Milieu of Atopic Dermatitis Skin Subverts the Innate Immune Response to Vaccinia Virus | Immunity | 2006 | 322 |
34 | Standard classification and pathophysiology of rosacea: The 2017 update by the National Rosacea Society Expert Committee | Journal of the American Academy of Dermatology | 2018 | 321 |
35 | Implanted hair follicle stem cells form Schwann cells that support repair of severed peripheral nerves | Proceedings of the National Academy of Sciences of the United States of America | 2005 | 317 |
36 | Plasmacytoid dendritic cells sense skin injury and promote wound healing through type I interferons | Journal of Experimental Medicine | 2010 | 317 |
37 | Antimicrobial Peptides: Old Molecules with New Ideas | Journal of Investigative Dermatology | 2012 | 317 |
38 | Microbial Symbiosis with the Innate Immune Defense System of the Skin | Journal of Investigative Dermatology | 2011 | 297 |
39 | Biology and clinical relevance of naturally occurring antimicrobial peptides | Journal of Allergy and Clinical Immunology | 2002 | 286 |
40 | A role for human skin–resident T cells in wound healing | Journal of Experimental Medicine | 2009 | 283 |
41 | TLR2 Expression Is Increased in Rosacea and Stimulates Enhanced Serine Protease Production by Keratinocytes | Journal of Investigative Dermatology | 2011 | 279 |
42 | Efficacy and safety of lebrikizumab (an anti-IL-13 monoclonal antibody) in adults with moderate-to-severe atopic dermatitis inadequately controlled by topical corticosteroids: A randomized, placebo-controlled phase II trial (TREBLE) | Journal of the American Academy of Dermatology | 2018 | 277 |
43 | Antimicrobial Property of Lauric Acid Against Propionibacterium Acnes: Its Therapeutic Potential for Inflammatory Acne Vulgaris | Journal of Investigative Dermatology | 2009 | 273 |
44 | Staphylococcus aureus Exploits Epidermal Barrier Defects in Atopic Dermatitis to Trigger Cytokine Expression | Journal of Investigative Dermatology | 2016 | 273 |
45 | Guidelines of care for the management of atopic dermatitis | Journal of the American Academy of Dermatology | 2014 | 270 |
46 | Efficient Generation of Human iPSCs by a Synthetic Self-Replicative RNA | Cell Stem Cell | 2013 | 262 |
47 | The molecular pathology of rosacea | Journal of Dermatological Science | 2009 | 255 |
48 | Efficacy and Safety of Lebrikizumab, a High-Affinity Interleukin 13 Inhibitor, in Adults With Moderate to Severe Atopic Dermatitis | JAMA Dermatology | 2020 | 255 |
49 | Cathelicidin deficiency predisposes to eczema herpeticum | Journal of Allergy and Clinical Immunology | 2006 | 254 |
50 | Cathelicidin Anti-Microbial Peptide Expression in Sweat, an Innate Defense System for the Skin | Journal of Investigative Dermatology | 2002 | 251 |