| CPAP for Prevention of Cardiovascular Events in Obstructive Sleep Apnea | New England Journal of Medicine | 2016 | 994 |
| The economic burden of physical inactivity: a global analysis of major non-communicable diseases | Lancet, The | 2016 | 946 |
| The progress in understanding and treatment of diabetic retinopathy | Progress in Retinal and Eye Research | 2016 | 449 |
| A Prospective Study of Sudden Cardiac Death among Children and Young Adults | New England Journal of Medicine | 2016 | 396 |
| Lipid-Based Drug Delivery Systems in Cancer Therapy: What Is Available and What Is Yet to Come | Pharmacological Reviews | 2016 | 361 |
| Comparison of Clinical Outcomes and Adverse Events Associated With Glucose-Lowering Drugs in Patients With Type 2 Diabetes: A Meta-analysis | JAMA - Journal of the American Medical Association | 2016 | 253 |
| The Role of Tumor-Infiltrating Lymphocytes in Development, Progression, and Prognosis of Non-Small Cell Lung Cancer | Journal of Thoracic Oncology | 2016 | 229 |
| Treatment of chronic hepatitis D with the entry inhibitor myrcludex B: First results of a phase Ib/IIa study | Journal of Hepatology | 2016 | 222 |
| Radiological differentiation of optic neuritis with myelin oligodendrocyte glycoprotein antibodies, aquaporin-4 antibodies, and multiple sclerosis | Multiple Sclerosis Journal | 2016 | 198 |
| The frontotemporal dementia-motor neuron disease continuum | Lancet, The | 2016 | 191 |
| Anti-MOG antibody: The history, clinical phenotype, and pathogenicity of a serum biomarker for demyelination | Autoimmunity Reviews | 2016 | 177 |
| Site-specific phosphorylation of tau inhibits amyloid-β toxicity in Alzheimer's mice | Science | 2016 | 168 |
| Cerebral cavernous malformations arise from endothelial gain of MEKK3-KLF2/4 signalling | Nature | 2016 | 164 |
| Exome-based analysis of cardiac arrhythmia, respiratory control, and epilepsy genes in sudden unexpected death in epilepsy | Annals of Neurology | 2016 | 162 |
| Human adult neurogenesis across the ages: An immunohistochemical study | Neuropathology and Applied Neurobiology | 2016 | 154 |
| Spatial Transcriptome for the Molecular Annotation of Lineage Fates and Cell Identity in Mid-gastrula Mouse Embryo | Developmental Cell | 2016 | 147 |
| Iron and dopamine: a toxic couple | Brain | 2016 | 142 |
| Programmed death ligand 1 expression in triple-negative breast cancer is associated with tumour-infiltrating lymphocytes and improved outcome | Histopathology | 2016 | 138 |
| HER2 Amplification and HER2 Mutation Are Distinct Molecular Targets in Lung Cancers | Journal of Thoracic Oncology | 2016 | 137 |
| Pulmonary veno-occlusive disease | European Respiratory Journal | 2016 | 134 |
| First-in-human application of the novel hepatitis B and hepatitis D virus entry inhibitor myrcludex B | Journal of Hepatology | 2016 | 132 |
| Too much medicine in older people? Deprescribing through shared decision making | BMJ, The | 2016 | 130 |
| Central neural control of the cardiovascular system: current perspectives | American Journal of Physiology - Advances in Physiology Education | 2016 | 129 |
| Treatment Adherence and Its Impact on Disease-Free Survival in the Breast International Group 1-98 Trial of Tamoxifen and Letrozole, Alone and in Sequence | Journal of Clinical Oncology | 2016 | 127 |
| Effects of the Mediterranean Diet on Cardiovascular Outcomes-A Systematic Review and Meta-Analysis | PLoS ONE | 2016 | 108 |
