| # | Title | Journal | Year | Citations |
|---|
|
| 1 | The Genome Sequence of Drosophila melanogaster | Science | 2000 | 5,617 |
| 2 | Biodiversity loss and its impact on humanity | Nature | 2012 | 5,240 |
| 3 | A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase | Nature Genetics | 1995 | 5,210 |
| 4 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,789 |
| 5 | Functional profiling of the Saccharomyces cerevisiae genome | Nature | 2002 | 4,011 |
| 6 | Rebuilding community ecology from functional traits | Trends in Ecology and Evolution | 2006 | 3,652 |
| 7 | Integrating animal temperament within ecology and evolution | Biological Reviews | 2007 | 2,791 |
| 8 | Habitat fragmentation and its lasting impact on Earth’s ecosystems | Science Advances | 2015 | 2,751 |
| 9 | The diversity–stability debate | Nature | 2000 | 2,533 |
| 10 | Regulation of Neuronal Survival by the Serine-Threonine Protein Kinase Akt | Science | 1997 | 2,326 |
| 11 | Endocrine Regulation of Energy Metabolism by the Skeleton | Cell | 2007 | 2,198 |
| 12 | The Genetic Landscape of a Cell | Science | 2010 | 1,962 |
| 13 | A global synthesis reveals biodiversity loss as a major driver of ecosystem change | Nature | 2012 | 1,815 |
| 14 | Selecting pseudo‐absences for species distribution models: how, where and how many? | Methods in Ecology and Evolution | 2012 | 1,806 |
| 15 | A syndrome of altered cardiovascular, craniofacial, neurocognitive and skeletal development caused by mutations in TGFBR1 or TGFBR2 | Nature Genetics | 2005 | 1,584 |
| 16 | Natural selection and the heritability of fitness components | Heredity | 1987 | 1,571 |
| 17 | Variation in δ15N and δ13C trophic fractionation: Implications for aquatic food web studies | Limnology and Oceanography | 2001 | 1,544 |
| 18 | Direct Regulation of the Akt Proto-Oncogene Product by Phosphatidylinositol-3,4-bisphosphate | Science | 1997 | 1,447 |
| 19 | A mesoscale phytoplankton bloom in the polar Southern Ocean stimulated by iron fertilization | Nature | 2000 | 1,437 |
| 20 | The return of the variance: intraspecific variability in community ecology | Trends in Ecology and Evolution | 2012 | 1,376 |
| 21 | The inner junction complex of the cilia is an interaction hub that involves tubulin post-translational modifications | ELife | 2020 | 1,304 |
| 22 | Superoxide dismutases: Dual roles in controlling ROS damage and regulating ROS signaling | Journal of Cell Biology | 2018 | 1,255 |
| 23 | High plant diversity is needed to maintain ecosystem services | Nature | 2011 | 1,250 |
| 24 | A Proteome-Scale Map of the Human Interactome Network | Cell | 2014 | 1,240 |
| 25 | Impacts of plant diversity on biomass production increase through time because of species complementarity | Proceedings of the National Academy of Sciences of the United States of America | 2007 | 1,218 |
| 26 | Species abundance distributions: moving beyond single prediction theories to integration within an ecological framework | Ecology Letters | 2007 | 1,155 |
| 27 | The cholinergic system in the pathophysiology and treatment of Alzheimer’s disease | Brain | 2018 | 1,116 |
| 28 | Extinction Rates of North American Freshwater Fauna | Conservation Biology | 1999 | 1,051 |
| 29 | BrafV600E cooperates with Pten loss to induce metastatic melanoma | Nature Genetics | 2009 | 1,038 |
| 30 | From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus | Nature | 2010 | 1,034 |
| 31 | The functional role of producer diversity in ecosystems | American Journal of Botany | 2011 | 1,028 |
| 32 | Climate change, adaptation, and phenotypic plasticity: the problem and the evidence | Evolutionary Applications | 2014 | 999 |
| 33 | Gene Regulation at the Single-Cell Level | Science | 2005 | 987 |
| 34 | Speciation through sensory drive in cichlid fish | Nature | 2008 | 965 |
| 35 | Membrane Phosphatidylserine Regulates Surface Charge and Protein Localization | Science | 2008 | 935 |
| 36 | PRIMARY CONSUMER δ13C AND δ15N AND THE TROPHIC POSITION OF AQUATIC CONSUMERS | Ecology | 1999 | 930 |
| 37 | Systematic Review of Intestinal Microbiota Transplantation (Fecal Bacteriotherapy) for Recurrent Clostridium difficile Infection | Clinical Infectious Diseases | 2011 | 889 |
| 38 | PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest | Nature Medicine | 2002 | 884 |
| 39 | The genetics of caloric restriction in Caenorhabditis elegans | Proceedings of the National Academy of Sciences of the United States of America | 1998 | 874 |
| 40 | Comparison of aquatic food chains using nitrogen isotopes. | Proceedings of the National Academy of Sciences of the United States of America | 1996 | 862 |
| 41 | Contemporary evolution meets conservation biology | Trends in Ecology and Evolution | 2003 | 862 |
| 42 | Improving the forecast for biodiversity under climate change | Science | 2016 | 843 |
| 43 | The experimental evolution of specialists, generalists, and the maintenance of diversity | Journal of Evolutionary Biology | 2002 | 831 |
| 44 | Functional traits and the growth–mortality trade‐off in tropical trees | Ecology | 2010 | 821 |
| 45 | Warming experiments underpredict plant phenological responses to climate change | Nature | 2012 | 801 |
| 46 | Big brains, enhanced cognition, and response of birds to novel environments | Proceedings of the National Academy of Sciences of the United States of America | 2005 | 798 |
| 47 | Conserved microtubule–actin interactions in cell movement and morphogenesis | Nature Cell Biology | 2003 | 796 |
| 48 | Human methylenetetrahydrofolate reductase: isolation of cDNA, mapping and mutation identification | Nature Genetics | 1994 | 782 |
| 49 | Inbreeding depression in the wild | Heredity | 1999 | 780 |
| 50 | The statistical analysis of mitochondrial DNA polymorphisms: chi 2 and the problem of small samples. | Molecular Biology and Evolution | 1989 | 763 |
