| Concurrent chemotherapy and pelvic radiation therapy compared with pelvic radiation therapy alone as adjuvant therapy after radical surgery in high-risk early-stage cancer of the cervix | Journal of Clinical Oncology | 2000 | 1.7K |
| Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome | Nature Cell Biology | 2000 | 1.2K |
| Maternal care, hippocampal synaptogenesis and cognitive development in rats | Nature Neuroscience | 2000 | 968 |
| Use of oral corticosteroids and risk of fractures | Journal of Bone and Mineral Research | 2000 | 931 |
| Importance of replication in microarray gene expression studies: statistical methods and evidence from repetitive cDNA hybridizations | Proceedings of the National Academy of Sciences of the United States of America | 2000 | 703 |
| Variations in maternal care in infancy regulate the development of stress reactivity | Biological Psychiatry | 2000 | 475 |
| Social support, depression, and mortality during the first year after myocardial infarction | Circulation | 2000 | 468 |
| The effects of early rearing environment on the development of GABAA and central benzodiazepine receptor levels and novelty-induced fearfulness in the rat | Neuropsychopharmacology | 2000 | 449 |
| Variations in maternal behaviour are associated with differences in oxytocin receptor levels in the rat | Journal of Neuroendocrinology | 2000 | 358 |
| Influence of neonatal rearing conditions on stress-induced adrenocorticotropin responses and norepinepherine release in the hypothalamic paraventricular nucleus | Journal of Neuroendocrinology | 2000 | 344 |
| ARSACS, a spastic ataxia common in northeastern Québec, is caused by mutations in a new gene encoding an 11.5-kb ORF | Nature Genetics | 2000 | 332 |
| Marrow stromal cells for cellular cardiomyoplasty: feasibility and potential clinical advantages | Journal of Thoracic and Cardiovascular Surgery | 2000 | 327 |
| Effects of experimental heart failure on atrial cellular and ionic electrophysiology | Circulation | 2000 | 317 |
| The mental health of Aboriginal peoples: transformations of identity and community | Canadian Journal of Psychiatry | 2000 | 300 |
| Polymorphisms in genes involved in folate metabolism as maternal risk factors for Down syndrome | American Journal of Human Genetics | 2000 | 285 |
| Behavioral insensitivity to restraint stress, absent fear suppression of behavior and impaired spatial learning in transgenic rats with hippocampal neuropeptide Y overexpression | Proceedings of the National Academy of Sciences of the United States of America | 2000 | 271 |
| The Ginkgo biloba extract (EGb 761) protects hippocampal neurons against cell death induced by beta-amyloid | European Journal of Neuroscience | 2000 | 265 |
| Mutations in NYX, encoding the leucine-rich proteoglycan nyctalopin, cause X-linked complete congenital stationary night blindness | Nature Genetics | 2000 | 265 |
| Normative data for iliac bone histomorphometry in growing children | Bone | 2000 | 259 |
| Cellular localization of gene expression for progranulin | Journal of Histochemistry and Cytochemistry | 2000 | 256 |
| Insulin-like growth factor physiology and cancer risk | European Journal of Cancer | 2000 | 248 |
| Activation of cdc42, rac, PAK, and rho-kinase in response to hepatocyte growth factor differentially regulates epithelial cell colony spreading and dissociation | Molecular Biology of the Cell | 2000 | 242 |
| Selective DNA binding and association with the CREB binding protein coactivator contribute to differential activation of alpha/beta interferon genes by interferon regulatory factors 3 and 7 | Molecular and Cellular Biology | 2000 | 236 |
| Regulation of histone deacetylase 4 by binding of 14-3-3 proteins | Molecular and Cellular Biology | 2000 | 232 |
| Neuroprotective abilities of resveratrol and other red wine constituents against nitric oxide-related toxicity in cultured hippocampal neurons | British Journal of Pharmacology | 2000 | 231 |
