| Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1 | Nature | 1998 | 655 |
| Identification and classification of p53-regulated genes | Proceedings of the National Academy of Sciences of the United States of America | 1999 | 386 |
| Genetic determinants of p53-induced apoptosis and growth arrest | Genes and Development | 1996 | 374 |
| Comparing the DNA hypermethylome with gene mutations in human colorectal cancer | PLoS Genetics | 2007 | 272 |
| Role of NADPH oxidase in arsenic-induced reactive oxygen species formation and cytotoxicity in myeloid leukemia cells | Proceedings of the National Academy of Sciences of the United States of America | 2004 | 192 |
| Design and anticipated outcomes of the eMERGE-PGx project: a multicenter pilot for preemptive pharmacogenomics in electronic health record systems | Clinical Pharmacology and Therapeutics | 2014 | 180 |
| Chaperone-facilitated copper binding is a property common to several classes of familial amyotrophic lateral sclerosis-linked superoxide dismutase mutants | Proceedings of the National Academy of Sciences of the United States of America | 1998 | 143 |
| Mutation analysis of LMX1B gene in nail-patella syndrome patients | American Journal of Human Genetics | 1998 | 142 |
| Polymerase delta variants in RER colorectal tumours | Nature Genetics | 1995 | 120 |
| Convergence of mutation and epigenetic alterations identifies common genes in cancer that predict for poor prognosis | PLoS Medicine | 2008 | 113 |
| CDX2 is mutated in a colorectal cancer with normal APC/beta-catenin signaling | Oncogene | 1999 | 112 |
| Genetic Association of Major Depression With Atypical Features and Obesity-Related Immunometabolic Dysregulations | JAMA Psychiatry | 2017 | 109 |
| Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia | Translational Psychiatry | 2017 | 100 |
| Expression of aquaporin 5 (AQP5) promotes tumor invasion in human non small cell lung cancer | PLoS ONE | 2008 | 97 |
| Molecular genetic overlap in bipolar disorder, schizophrenia, and major depressive disorder | World Journal of Biological Psychiatry | 2014 | 82 |
| Acute promyelocytic leukemia: recent advances in therapy and molecular basis of response to arsenic therapies | Current Opinion in Hematology | 2005 | 63 |
| Clustering of hypermethylated genes in neuroblastoma | Genes Chromosomes and Cancer | 2003 | 62 |
| Human AQP5 plays a role in the progression of chronic myelogenous leukemia (CML) | PLoS ONE | 2008 | 56 |
| What is new with 22q? An update from the 22q and You Center at the Children's Hospital of Philadelphia | American Journal of Medical Genetics, Part A | 2018 | 54 |
| A first trial of retrospective collaboration for positional cloning in complex inheritance: assay of the cytokine region on chromosome 5 by the consortium on asthma genetics (COAG) | Proceedings of the National Academy of Sciences of the United States of America | 2000 | 41 |
| Oxidative stress and iron are implicated in fragmenting vacuoles of Saccharomyces cerevisiae lacking Cu,Zn-superoxide dismutase | Journal of Biological Chemistry | 1999 | 40 |
| MORC-1 Integrates Nuclear RNAi and Transgenerational Chromatin Architecture to Promote Germline Immortality | Developmental Cell | 2017 | 36 |
| Mitochondrial Replacement Techniques--Implications for the Clinical Community | New England Journal of Medicine | 2016 | 35 |
| Multivesicular bodies mediate long-range retrograde NGF-TrkA signaling | ELife | 2018 | 33 |
| Epigenetic silencing of human T (brachyury homologue) gene in non-small-cell lung cancer | Biochemical and Biophysical Research Communications | 2008 | 31 |
