| Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease | Nature | 2012 | 3.2K |
| Comparison of risk prediction using the CKD-EPI equation and the MDRD study equation for estimated glomerular filtration rate | JAMA - Journal of the American Medical Association | 2012 | 658 |
| Risk prediction models: II. External validation, model updating, and impact assessment | Heart | 2012 | 609 |
| Risk prediction models: I. Development, internal validation, and assessing the incremental value of a new (bio)marker | Heart | 2012 | 509 |
| Meta-analysis identifies six new susceptibility loci for atrial fibrillation | Nature Genetics | 2012 | 429 |
| Detectable clonal mosaicism from birth to old age and its relationship to cancer | Nature Genetics | 2012 | 409 |
| Detectable clonal mosaicism and its relationship to aging and cancer | Nature Genetics | 2012 | 409 |
| Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals | PLoS Genetics | 2012 | 326 |
| Twenty-two-year trends in incidence of myocardial infarction, coronary heart disease mortality, and case fatality in 4 US communities, 1987-2008 | Circulation | 2012 | 249 |
| Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci | American Journal of Human Genetics | 2012 | 214 |
| Association of HbA1c levels with vascular complications and death in patients with type 2 diabetes: evidence of glycaemic thresholds | Diabetologia | 2012 | 212 |
| Vitamin D-related genetic variation, plasma vitamin D, and risk of lethal prostate cancer: a prospective nested case-control study | Journal of the National Cancer Institute | 2012 | 177 |
| The impact of treatment noncompliance on mortality in people with type 2 diabetes | Diabetes Care | 2012 | 143 |
| Corticosteroid therapy in IgA nephropathy | Journal of the American Society of Nephrology: JASN | 2012 | 139 |
| Novel markers of kidney function as predictors of ESRD, cardiovascular disease, and mortality in the general population | American Journal of Kidney Diseases | 2012 | 134 |
| Prediction of incident heart failure in general practice: the Atherosclerosis Risk in Communities (ARIC) Study | Circulation: Heart Failure | 2012 | 128 |
| Higher dietary fructose is associated with impaired hepatic adenosine triphosphate homeostasis in obese individuals with type 2 diabetes | Hepatology | 2012 | 125 |
| A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci | PLoS Genetics | 2012 | 117 |
| Comparisons of high-dose and combination nicotine replacement therapy, varenicline, and bupropion for smoking cessation: a systematic review and multiple treatment meta-analysis | Annals of Medicine | 2012 | 114 |
| Factors affecting brain structure in men with HIV disease in the post-HAART era | Neuroradiology | 2012 | 100 |
| Randomized, controlled trial of home telemanagement in patients with ulcerative colitis (UC HAT) | Inflammatory Bowel Diseases | 2012 | 100 |
| Modulation of the metabolism of airborne pollutants by glucoraphanin-rich and sulforaphane-rich broccoli sprout beverages in Qidong, China | Carcinogenesis | 2012 | 94 |
| Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAM | Molecular Psychiatry | 2012 | 93 |
| Net endogenous acid production is associated with a faster decline in GFR in African Americans | Kidney International | 2012 | 88 |
| Neutrophil gelatinase-associated lipocalin (NGAL) and kidney injury molecule 1 (KIM-1) as predictors of incident CKD stage 3: the Atherosclerosis Risk in Communities (ARIC) Study | American Journal of Kidney Diseases | 2012 | 85 |
