| # | Title | Journal | Year | Citations |
|---|
|
| 1 | Neurotoxic reactive astrocytes are induced by activated microglia | Nature | 2017 | 5,404 |
| 2 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,789 |
| 3 | Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 | Cell Death and Differentiation | 2018 | 4,451 |
| 4 | Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme. | Proceedings of the National Academy of Sciences of the United States of America | 1990 | 3,084 |
| 5 | Protein aggregation and neurodegenerative disease | Nature Medicine | 2004 | 2,889 |
| 6 | Pathways towards and away from Alzheimer's disease | Nature | 2004 | 2,740 |
| 7 | The Alzheimer's disease neuroimaging initiative (ADNI): MRI methods | Journal of Magnetic Resonance Imaging | 2008 | 2,655 |
| 8 | Melanopsin-Containing Retinal Ganglion Cells: Architecture, Projections, and Intrinsic Photosensitivity | Science | 2002 | 2,315 |
| 9 | Adult Neurogenesis in the Mammalian Brain: Significant Answers and Significant Questions | Neuron | 2011 | 2,246 |
| 10 | NITRIC OXIDE: A Physiologic Messenger Molecule | Annual Review of Biochemistry | 1994 | 2,194 |
| 11 | Widespread transcription at neuronal activity-regulated enhancers | Nature | 2010 | 2,159 |
| 12 | Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure | Cell | 2016 | 1,746 |
| 13 | Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum. | Proceedings of the National Academy of Sciences of the United States of America | 1989 | 1,732 |
| 14 | Mediation of Poly(ADP-Ribose) Polymerase-1-Dependent Cell Death by Apoptosis-Inducing Factor | Science | 2002 | 1,693 |
| 15 | Nitric oxide synthase and neuronal NADPH diaphorase are identical in brain and peripheral tissues. | Proceedings of the National Academy of Sciences of the United States of America | 1991 | 1,660 |
| 16 | ADULT NEUROGENESIS IN THE MAMMALIAN CENTRAL NERVOUS SYSTEM | Annual Review of Neuroscience | 2005 | 1,655 |
| 17 | From circuits to behaviour in the amygdala | Nature | 2015 | 1,601 |
| 18 | Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis | Nature | 2007 | 1,544 |
| 19 | PINK1-dependent recruitment of Parkin to mitochondria in mitophagy | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 1,450 |
| 20 | Huntington's disease: from molecular pathogenesis to clinical treatment | Lancet Neurology, The | 2011 | 1,436 |
| 21 | β-Lactam antibiotics offer neuroprotection by increasing glutamate transporter expression | Nature | 2005 | 1,400 |
| 22 | Nitric oxide synthase protein and mRNA are discretely localized in neuronal populations of the mammalian CNS together with NADPH diaphorase | Neuron | 1991 | 1,392 |
| 23 | Wnt signalling regulates adult hippocampal neurogenesis | Nature | 2005 | 1,386 |
| 24 | RAFT1: A mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs | Cell | 1994 | 1,371 |
| 25 | Selective loss of glial glutamate transporter GLT‐1 in amyotrophic lateral sclerosis | Annals of Neurology | 1995 | 1,369 |
| 26 | A new member of the frizzled family from Drosophila functions as a Wingless receptor | Nature | 1996 | 1,357 |
| 27 | Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial | Journal of Psychopharmacology | 2016 | 1,356 |
| 28 | Protein S-nitrosylation: a physiological signal for neuronal nitric oxide | Nature Cell Biology | 2001 | 1,331 |
| 29 | Reactive astrocyte nomenclature, definitions, and future directions | Nature Neuroscience | 2021 | 1,292 |
| 30 | MAPK cascade signalling and synaptic plasticity | Nature Reviews Neuroscience | 2004 | 1,282 |
| 31 | A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants | Nature Genetics | 2016 | 1,237 |
| 32 | Hydroxylation of 5-Methylcytosine by TET1 Promotes Active DNA Demethylation in the Adult Brain | Cell | 2011 | 1,214 |
| 33 | Expression of a mitogen-inducible cyclooxygenase in brain neurons: Regulation by synaptic activity and glucocorticoids | Neuron | 1993 | 1,194 |
| 34 | Psilocybin can occasion mystical-type experiences having substantial and sustained personal meaning and spiritual significance | Psychopharmacology | 2006 | 1,184 |
| 35 | Melanopsin-expressing ganglion cells in primate retina signal colour and irradiance and project to the LGN | Nature | 2005 | 1,164 |
| 36 | GABA regulates synaptic integration of newly generated neurons in the adult brain | Nature | 2006 | 1,153 |
| 37 | Zika Virus Infects Human Cortical Neural Progenitors and Attenuates Their Growth | Cell Stem Cell | 2016 | 1,146 |
| 38 | MOLECULAR PATHOPHYSIOLOGY OF PARKINSON'S DISEASE | Annual Review of Neuroscience | 2005 | 1,131 |
| 39 | Arc, a growth factor and activity-regulated gene, encodes a novel cytoskeleton-associated protein that is enriched in neuronal dendrites | Neuron | 1995 | 1,129 |
| 40 | Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease | Nature Neuroscience | 2019 | 1,121 |
| 41 | The mTOR Kinase Differentially Regulates Effector and Regulatory T Cell Lineage Commitment | Immunity | 2009 | 1,102 |
| 42 | H 2 S Signals Through Protein S-Sulfhydration | Science Signaling | 2009 | 1,075 |
| 43 | Melanopsin and rod–cone photoreceptive systems account for all major accessory visual functions in mice | Nature | 2003 | 1,068 |
| 44 | Hippocampal place-cell sequences depict future paths to remembered goals | Nature | 2013 | 1,055 |
| 45 | Fasting: Molecular Mechanisms and Clinical Applications | Cell Metabolism | 2014 | 1,053 |
| 46 | D-Serine is an endogenous ligand for the glycine site of the N-methyl-D-aspartate receptor | Proceedings of the National Academy of Sciences of the United States of America | 2000 | 1,041 |
| 47 | Neuroscience Needs Behavior: Correcting a Reductionist Bias | Neuron | 2017 | 1,033 |
| 48 | Rapid increase of an immediate early gene messenger RNA in hippocampal neurons by synaptic NMDA receptor activation | Nature | 1989 | 1,025 |
| 49 | Homer: a protein that selectively binds metabotropic glutamate receptors | Nature | 1997 | 1,022 |
| 50 | Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease | Nature Medicine | 1999 | 1,010 |
