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| 2 | A long-term evaluation of once-daily inhaled tiotropium in chronic obstructive pulmonary disease | European Respiratory Journal | 2002 | 833 |
| 3 | Effect of Out-of-Hospital Pediatric Endotracheal Intubation on Survival and Neurological Outcome | JAMA - Journal of the American Medical Association | 2000 | 797 |
| 4 | Estrogen plus Progestin and Colorectal Cancer in Postmenopausal Women | New England Journal of Medicine | 2004 | 612 |
| 5 | Beraprost therapy for pulmonary arterial hypertension | Journal of the American College of Cardiology | 2003 | 583 |
| 6 | Measurement of Total Serum Testosterone in Adult Men: Comparison of Current Laboratory MethodsVersusLiquid Chromatography-Tandem Mass Spectrometry | Journal of Clinical Endocrinology and Metabolism | 2004 | 547 |
| 7 | Antimicrobial Peptides from Human Platelets | Infection and Immunity | 2002 | 527 |
| 8 | (null) | Cancer Causes and Control | 2002 | 489 |
| 9 | Benefits of Supplemental Oxygen in Exercise Training in Nonhypoxemic Chronic Obstructive Pulmonary Disease Patients | American Journal of Respiratory and Critical Care Medicine | 2003 | 319 |
| 10 | Exercise capacity as a predictor of survival among ambulatory patients with end-stage renal disease | Kidney International | 2004 | 291 |
| 11 | Dose-response effect of oxygen on hyperinflation and exercise endurance in nonhypoxaemic COPD patients | European Respiratory Journal | 2001 | 289 |
| 12 | Candida albicans RIM101
pH Response Pathway Is Required for Host-Pathogen Interactions | Infection and Immunity | 2000 | 277 |
| 13 | Metabolic control analysis in drug discovery and disease | Nature Biotechnology | 2002 | 275 |
| 14 | Continuous Probabilistic Prediction of Angiographically Significant Coronary Artery Disease Using Electron Beam Tomography | Circulation | 2002 | 264 |
| 15 | Functional and Structural Diversity in the Als Protein Family of Candida albicans | Journal of Biological Chemistry | 2004 | 263 |
| 16 | HMG CoA reductase inhibitor (statin) and aortic valve calcium | Lancet, The | 2002 | 258 |
| 17 | Molecular, Endocrine, and Genetic Mechanisms of Arterial Calcification | Endocrine Reviews | 2004 | 253 |
| 18 | Screening patients with chest pain in the emergency department using electron beam tomography: a follow-up study | Journal of the American College of Cardiology | 2001 | 252 |
| 19 | Intestinal permeability, leaky gut, and intestinal disorders | Current Gastroenterology Reports | 1999 | 236 |
| 20 | Rates of progression of coronary calcium by electron beam tomography | American Journal of Cardiology | 2000 | 235 |
| 21 | The Importance of Health Insurance as a Determinant of Cancer Screening: Evidence from the Women's Health Initiative | Preventive Medicine | 2000 | 232 |
| 22 | Phase I Evaluation of the Safety and Pharmacokinetics of Murine-Derived Anticryptococcal Antibody 18B7 in Subjects with Treated Cryptococcal Meningitis | Antimicrobial Agents and Chemotherapy | 2005 | 228 |
| 23 | Loss of Tubular Bone Morphogenetic Protein—7 in Diabetic Nephropathy | Journal of the American Society of Nephrology: JASN | 2001 | 218 |
| 24 | Combined Use of Computed Tomography Coronary Calcium Scores and C-Reactive Protein Levels in Predicting Cardiovascular Events in Nondiabetic Individuals | Circulation | 2002 | 213 |
| 25 | Candida albicans Als1p: an adhesin that is a downstream effector of the EFG1 filamentation pathway | Molecular Microbiology | 2002 | 208 |
| 26 | Mechanism of Fluconazole Resistance in
Candida krusei | Antimicrobial Agents and Chemotherapy | 1998 | 206 |
| 27 | Connective tissue growth factor in tubulointerstitial injury of diabetic nephropathy | Kidney International | 2001 | 196 |
| 28 | Candida albicans Mds3p, a Conserved Regulator of pH Responses and Virulence Identified Through Insertional Mutagenesis | Genetics | 2002 | 191 |
| 29 | The Spirometric Efficacy of Once-Daily Dosing With Tiotropium in Stable COPD | Chest | 2000 | 189 |
| 30 | Calcineurin Is Essential for
Candida albicans
Survival in Serum and Virulence | Eukaryotic Cell | 2003 | 186 |
| 31 | Clinical and demographic predictors of exercise capacity in end-stage renal disease | American Journal of Kidney Diseases | 2002 | 183 |
| 32 | How well do clinicians estimate patients’ adherence to combination antiretroviral therapy? | Journal of General Internal Medicine | 2002 | 183 |
| 33 | Combination Therapy with Amphotericin B Lipid Complex and Caspofungin Acetate of Disseminated Zygomycosis in Diabetic Ketoacidotic Mice | Antimicrobial Agents and Chemotherapy | 2005 | 183 |
| 34 | Local Anesthesia for Inguinal Hernia Repair Step-by-Step Procedure | Annals of Surgery | 1994 | 180 |
| 35 | Role of Hyphal Formation in Interactions of
Candida albicans
with Endothelial Cells | Infection and Immunity | 2000 | 180 |
| 36 | Deciphering the pathways of germ cell apoptosis in the testis | Journal of Steroid Biochemistry and Molecular Biology | 2003 | 177 |
| 37 | BMP7 antagonizes TGF-β-dependent fibrogenesis in mesangial cells | American Journal of Physiology - Renal Physiology | 2003 | 174 |
| 38 | Gleevec (STI571) Influences Metabolic Enzyme Activities and Glucose Carbon Flow toward Nucleic Acid and Fatty Acid Synthesis in Myeloid Tumor Cells | Journal of Biological Chemistry | 2001 | 172 |
| 39 | The effect of thiamine supplementation on tumour proliferation | FEBS Journal | 2001 | 164 |
| 40 | Effects of transdermal testosterone gel on bone turnover markers and bone mineral density in hypogonadal men | Clinical Endocrinology | 2001 | 163 |
| 41 | Coronary Artery Calcification and Myocardial Perfusion in Asymptomatic Adults | Journal of the American College of Cardiology | 2006 | 162 |
| 42 | Intrathecal enzyme replacement therapy reduces lysosomal storage in the brain and meninges of the canine model of MPS I | Molecular Genetics and Metabolism | 2004 | 161 |
| 43 | Expression of the
Candida albicans
Gene
ALS1
in
Saccharomyces cerevisiae
Induces Adherence to Endothelial and Epithelial Cells | Infection and Immunity | 1998 | 155 |
| 44 | Biomaterials for abdominal wall hernia surgery and principles of their applications | Langenbecks Archiv Fur Chirurgie | 1994 | 153 |
| 45 | Ethnic Differences in the Prognostic Value of Coronary Artery Calcification for All-Cause Mortality | Journal of the American College of Cardiology | 2007 | 153 |
| 46 | Gene expression profile and histopathology of experimental bronchopulmonary dysplasia induced by prolonged oxidative stress | Free Radical Biology and Medicine | 2004 | 146 |
| 47 | NUTRITIONALMANAGEMENT OFMAINTENANCEDIALYSISPATIENTS: Why Aren't We Doing Better? | Annual Review of Nutrition | 2001 | 143 |
| 48 | Comparison of gene expression profiles between Peyronie's disease and Dupuytren's contracture | Urology | 2004 | 143 |
| 49 | A Treadmill Ramp Protocol Using Simultaneous Changes in Speed and Grade | Medicine and Science in Sports and Exercise | 2003 | 142 |
| 50 | Metabolic strategy of boar spermatozoa revealed by a metabolomic characterization | FEBS Letters | 2003 | 141 |
