| 1 | A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010 | Lancet, The | 2012 | 7,751 |
| 2 | Maternal and child undernutrition and overweight in low-income and middle-income countries | Lancet, The | 2013 | 5,286 |
| 3 | Hazards of heavy metal contamination | British Medical Bulletin | 2003 | 4,500 |
| 5 | BEAST 2.5: An advanced software platform for Bayesian evolutionary analysis | PLoS Computational Biology | 2019 | 3,411 |
| 6 | Genetic studies of body mass index yield new insights for obesity biology | Nature | 2015 | 3,267 |
| 7 | National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9·1 million participants | Lancet, The | 2011 | 2,804 |
| 8 | Biological, clinical and population relevance of 95 loci for blood lipids | Nature | 2010 | 2,721 |
| 9 | adegenet 1.3-1
: new tools for the analysis of genome-wide SNP data | Bioinformatics | 2011 | 2,674 |
| 10 | Global and regional burden of stroke during 1990–2010: findings from the Global Burden of Disease Study 2010 | Lancet, The | 2014 | 2,667 |
| 11 | National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2·7 million participants | Lancet, The | 2011 | 2,487 |
| 12 | Emerging fungal threats to animal, plant and ecosystem health | Nature | 2012 | 2,402 |
| 13 | Discovery and refinement of loci associated with lipid levels | Nature Genetics | 2013 | 2,324 |
| 14 | Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index | Nature Genetics | 2010 | 2,138 |
| 15 | The effect of malaria control on Plasmodium falciparum in Africa between 2000 and 2015 | Nature | 2015 | 2,110 |
| 16 | Estimates of the severity of coronavirus disease 2019: a model-based analysis | Lancet Infectious Diseases, The | 2020 | 2,099 |
| 17 | Substantial undocumented infection facilitates the rapid dissemination of novel coronavirus (SARS-CoV-2) | Science | 2020 | 2,081 |
| 18 | A genome-wide association study identifies novel risk loci for type 2 diabetes | Nature | 2007 | 2,002 |
| 19 | Approximate Bayesian Computation in Population Genetics | Genetics | 2002 | 1,930 |
| 20 | Current status of cadmium as an environmental health problem | Toxicology and Applied Pharmacology | 2009 | 1,867 |
| 21 | A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease | Nature Genetics | 2015 | 1,851 |
| 22 | The Global Syndemic of Obesity, Undernutrition, and Climate Change: The Lancet Commission report | Lancet, The | 2019 | 1,831 |
| 23 | Prediction models for diagnosis and prognosis of covid-19: systematic review and critical appraisal | BMJ, The | 0 | 1,782 |
| 24 | The State of US Health, 1990-2010 | JAMA - Journal of the American Medical Association | 2013 | 1,724 |
| 25 | New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk | Nature Genetics | 2010 | 1,657 |
| 26 | Contour-enhanced meta-analysis funnel plots help distinguish publication bias from other causes of asymmetry | Journal of Clinical Epidemiology | 2008 | 1,636 |
| 27 | Fruit and vegetable intake and the risk of cardiovascular disease, total cancer and all-cause mortality—a systematic review and dose-response meta-analysis of prospective studies | International Journal of Epidemiology | 2017 | 1,594 |
| 28 | The Burden of Primary Liver Cancer and Underlying Etiologies From 1990 to 2015 at the Global, Regional, and National Level | JAMA Oncology | 2017 | 1,458 |
| 29 | eBURST: Inferring Patterns of Evolutionary Descent among Clusters of Related Bacterial Genotypes from Multilocus Sequence Typing Data | Journal of Bacteriology | 2004 | 1,452 |
| 30 | Strategies for mitigating an influenza pandemic | Nature | 2006 | 1,425 |
| 31 | Hundreds of variants clustered in genomic loci and biological pathways affect human height | Nature | 2010 | 1,382 |
| 32 | The BUGS project: Evolution, critique and future directions | Statistics in Medicine | 2009 | 1,339 |
| 33 | Guidelines for Accurate and Transparent Health Estimates Reporting: the GATHER statement | Lancet, The | 2016 | 1,309 |
| 34 | Detecting pleiotropy in Mendelian randomisation studies with summary data and a continuous outcome | Statistics in Medicine | 2015 | 1,272 |
| 35 | Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps | Nature Genetics | 2018 | 1,266 |
| 36 | Large-scale association analysis identifies new risk loci for coronary artery disease | Nature Genetics | 2012 | 1,255 |
| 37 | Defining the role of common variation in the genomic and biological architecture of adult human height | Nature Genetics | 2014 | 1,251 |
| 38 | Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes | Nature Genetics | 2018 | 1,239 |
| 39 | Global, regional, and national trends in haemoglobin concentration and prevalence of total and severe anaemia in children and pregnant and non-pregnant women for 1995–2011: a systematic analysis of population-representative data | The Lancet Global Health | 2013 | 1,213 |
| 40 | New genetic loci link adipose and insulin biology to body fat distribution | Nature | 2015 | 1,199 |
| 41 | Guidelines for performing Mendelian randomization investigations | Wellcome Open Research | 2019 | 1,187 |
| 42 | Strategies for containing an emerging influenza pandemic in Southeast Asia | Nature | 2005 | 1,184 |
| 43 | Intake of vitamin D and risk of type 1 diabetes: a birth-cohort study | Lancet, The | 2001 | 1,181 |
| 44 | Prognosis of HIV-1-infected patients starting highly active antiretroviral therapy: a collaborative analysis of prospective studies | Lancet, The | 2002 | 1,175 |
| 45 | Common genetic determinants of vitamin D insufficiency: a genome-wide association study | Lancet, The | 2010 | 1,170 |
| 46 | Air pollution and lung cancer incidence in 17 European cohorts: prospective analyses from the European Study of Cohorts for Air Pollution Effects (ESCAPE) | Lancet Oncology, The | 2013 | 1,157 |
| 47 | The 2020 report of The Lancet Countdown on health and climate change: responding to converging crises | Lancet, The | 2021 | 1,123 |
| 48 | Global epidemiology, health burden and effective interventions for elevated blood pressure and hypertension | Nature Reviews Cardiology | 2021 | 1,113 |
| 49 | Sickle cell disease | Nature Reviews Disease Primers | 2018 | 1,107 |
| 50 | Development of Land Use Regression Models for PM2.5, PM2.5 Absorbance, PM10 and PMcoarse in 20 European Study Areas; Results of the ESCAPE Project | Environmental Science & Technology | 2012 | 1,105 |
