Optimization of intensity-modulated radiotherapy plans based on the equivalent uniform dose | International Journal of Radiation Oncology Biology Physics | 2002 | 297 |
mda-7 (IL-24) Mediates selective apoptosis in human melanoma cells by inducing the coordinated overexpression of the GADD family of genes by means of p38 MAPK | Proceedings of the National Academy of Sciences of the United States of America | 2002 | 275 |
Roles of ERBB family receptor tyrosine kinases, and downstream signaling pathways, in the control of cell growth and survival | Frontiers in Bioscience - Landmark | 2002 | 136 |
Ionizing radiation activates Erb-B receptor dependent Akt and p70 S6 kinase signaling in carcinoma cells | Oncogene | 2002 | 135 |
Pharmacologic mitogen-activated protein/extracellular signal-regulated kinase kinase/mitogen-activated protein kinase inhibitors interact synergistically with STI571 to induce apoptosis in Bcr/Abl-expressing human leukemia cells | Cancer Research | 2002 | 117 |
Identification and cloning of human polynucleotide phosphorylase, hPNPase old-35, in the context of terminal differentiation and cellular senescence | Proceedings of the National Academy of Sciences of the United States of America | 2002 | 95 |
Combined treatment with the checkpoint abrogator UCN-01 and MEK1/2 inhibitors potently induces apoptosis in drug-sensitive and -resistant myeloma cells through an IL-6-independent mechanism | Blood | 2002 | 89 |
Dm rather than Dw should be used in Monte Carlo treatment planning. For the proposition | Medical Physics | 2002 | 64 |
TNF-alpha signal transduction in rat neonatal cardiac myocytes: definition of pathways generating from the TNF-alpha receptor | FASEB Journal | 2002 | 62 |
Epidermal growth factor receptor dependence of radiation-induced transcription factor activation in human breast carcinoma cells | Molecular Biology of the Cell | 2002 | 55 |
mda-7 (IL-24): Signaling and Functional Roles | BioTechniques | 2002 | 52 |
CL100 expression is down-regulated in advanced epithelial ovarian cancer and its re-expression decreases its malignant potential | Oncogene | 2002 | 52 |
Inhibitors of MEK1/2 interact with UCN-01 to induce apoptosis and reduce colony formation in mammary and prostate carcinoma cells | Cancer Biology and Therapy | 2002 | 43 |
Diagnosis and management of patients with thyroid nodules | Journal of Surgical Oncology | 2002 | 41 |
Continuous lidocaine infusion for the relief of refractory malignant pain in a terminally ill pediatric cancer patient | Journal of Pediatric Hematology/Oncology | 2002 | 40 |
Cyclin kinase inhibitor p21 potentiates bile acid-induced apoptosis in hepatocytes that is dependent on p53 | Hepatology | 2002 | 37 |
Pharmocologic inhibitors of the mitogen activated protein kinase cascade have the potential to interact with ionizing radiation exposure to induce cell death in carcinoma cells by multiple mechanisms | Cancer Biology and Therapy | 2002 | 31 |
SAGE transcript profiles of normal primary human hepatocytes expressing oncogenic hepatitis B virus X protein | FASEB Journal | 2002 | 29 |
Bryostatin 1 increases 1-beta-D-arabinofuranosylcytosine-induced cytochrome c release and apoptosis in human leukemia cells ectopically expressing Bcl-x(L) | Journal of Pharmacology and Experimental Therapeutics | 2002 | 25 |
Phase I trial and correlative laboratory studies of bryostatin 1 (NSC 339555) and high-dose 1-B-D-arabinofuranosylcytosine in patients with refractory acute leukemia | Clinical Cancer Research | 2002 | 24 |
Radiosensitization of human glioma cells in vitro and in vivo with acyclovir and mutant HSV-TK75 expressed from adenovirus | International Journal of Radiation Oncology Biology Physics | 2002 | 20 |
Loss of the Bcl-2 phosphorylation loop domain is required to protect human myeloid leukemia cells from flavopiridol-mediated mitochondrial damage and apoptosis | Cancer Biology and Therapy | 2002 | 16 |
A decade of experience with transthoracic and transhiatal esophagectomy | American Journal of Surgery | 2002 | 16 |
Conversion of drug-induced differentiation to apoptosis by pharmacologic cyclin-dependent kinase inhibitors | Cell Cycle | 2002 | 14 |
Progression elevated gene-3, PEG-3, induces genomic instability in rodent and human tumor cells | Journal of Cellular Physiology | 2002 | 13 |