| Antibiotic resistance and its cost: is it possible to reverse resistance? | Nature Reviews Microbiology | 2010 | 1.4K |
| Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution | Nature Genetics | 2010 | 724 |
| Whole-genome resequencing reveals loci under selection during chicken domestication | Nature | 2010 | 718 |
| Intestinal stem cell replacement follows a pattern of neutral drift | Science | 2010 | 468 |
| Impact of body mass index and the metabolic syndrome on the risk of cardiovascular disease and death in middle-aged men | Circulation | 2010 | 433 |
| Ticagrelor versus clopidogrel in patients with ST-elevation acute coronary syndromes intended for reperfusion with primary percutaneous coronary intervention: A Platelet Inhibition and Patient Outcomes (PLATO) trial subgroup analysis | Circulation | 2010 | 392 |
| Dietary inorganic nitrate reverses features of metabolic syndrome in endothelial nitric oxide synthase-deficient mice | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 263 |
| Early life origins of chronic obstructive pulmonary disease | Thorax | 2010 | 257 |
| Modulation of Shigella virulence in response to available oxygen in vivo | Nature | 2010 | 235 |
| Bacteria penetrate the inner mucus layer before inflammation in the dextran sulfate colitis model | PLoS ONE | 2010 | 234 |
| Patterns of East Asian pig domestication, migration, and turnover revealed by modern and ancient DNA | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 212 |
| Plasma vitamin D and mortality in older men: a community-based prospective cohort study | American Journal of Clinical Nutrition | 2010 | 195 |
| Fine mapping the spatial distribution and concentration of unlabeled drugs within tissue micro-compartments using imaging mass spectrometry | PLoS ONE | 2010 | 179 |
| A chemotactic gradient sequestered on endothelial heparan sulfate induces directional intraluminal crawling of neutrophils | Blood | 2010 | 167 |
| Genome-wide synteny through highly sensitive sequence alignment: Satsuma | Bioinformatics | 2010 | 157 |
| Complement drives Th17 cell differentiation and triggers autoimmune arthritis | Journal of Experimental Medicine | 2010 | 157 |
| Direct angiotensin II type 2 receptor stimulation acts anti-inflammatory through epoxyeicosatrienoic acid and inhibition of nuclear factor kappaB | Hypertension | 2010 | 153 |
| The cyclotide cycloviolacin O2 from Viola odorata has potent bactericidal activity against Gram-negative bacteria | Journal of Antimicrobial Chemotherapy | 2010 | 149 |
| Rates and mechanisms of resistance development in Mycobacterium tuberculosis to a novel diarylquinoline ATP synthase inhibitor | Antimicrobial Agents and Chemotherapy | 2010 | 140 |
| Dabigatran and warfarin in vitamin K antagonist-naive and -experienced cohorts with atrial fibrillation | Circulation | 2010 | 138 |
| Absolute and relative risk of cardiovascular disease in men with prostate cancer: results from the Population-Based PCBaSe Sweden | Journal of Clinical Oncology | 2010 | 138 |
| VEGF receptor 2/-3 heterodimers detected in situ by proximity ligation on angiogenic sprouts | EMBO Journal | 2010 | 134 |
| Associations between Short Sleep Duration and Central Obesity in Women | Sleep | 2010 | 133 |
| Tobacco use during pregnancy and preeclampsia risk: effects of cigarette smoking and snuff | Hypertension | 2010 | 129 |
| Mechanisms of atelectasis in the perioperative period | Bailliere's Best Practice and Research in Clinical Anaesthesiology | 2010 | 128 |
