842
Articles
45.2K
Citations
6.6
avg. Impact Factor
96
h-index

Most Cited Articles of Cell and Systems Biology in 2016

TitleJournalYearCitations
Biology and Applications of CRISPR Systems: Harnessing Nature's Toolbox for Genome EngineeringCell2016715
Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic ScreensCell2016675
A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein ResponseCell2016518
A Compendium of Chromatin Contact Maps Reveals Spatially Active Regions in the Human GenomeCell Reports2016453
A Comprehensive, CRISPR-based Functional Analysis of Essential Genes in BacteriaCell2016367
Programmable RNA Tracking in Live Cells with CRISPR/Cas9Cell2016358
Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activationELife2016343
CRISPR Interference Efficiently Induces Specific and Reversible Gene Silencing in Human iPSCsCell Stem Cell2016271
Ribosome Footprint Profiling of Translation throughout the GenomeCell2016251
Recon 2.2: from reconstruction to model of human metabolismMetabolomics2016184
Methylome-wide Analysis of Chronic HIV Infection Reveals Five-Year Increase in Biological Age and Epigenetic Targeting of HLAMolecular Cell2016166
eIF3d is an mRNA cap-binding protein that is required for specialized translation initiationNature2016165
Rocaglates convert DEAD-box protein eIF4A into a sequence-selective translational repressorNature2016149
A Consensus Genome-scale Reconstruction of Chinese Hamster Ovary Cell MetabolismCell Systems2016145
The Cacti Microbiome: Interplay between Habitat-Filtering and Host-SpecificityFrontiers in Microbiology2016112
Multi-omic data integration enables discovery of hidden biological regularitiesNature Communications2016110
CRISPR Immunological Memory Requires a Host Factor for SpecificityMolecular Cell2016101
A Network of Conserved Synthetic Lethal Interactions for Exploration of Precision Cancer TherapyMolecular Cell201699
Protein-RNA Networks Regulated by Normal and ALS-Associated Mutant HNRNPA2B1 in the Nervous SystemNeuron201694
Role of the microbiome, probiotics, and 'dysbiosis therapy' in critical illnessCurrent Opinion in Critical Care201691
Versatile in vivo regulation of tumor phenotypes by dCas9-mediated transcriptional perturbationProceedings of the National Academy of Sciences of the United States of America201676
High-level ROR1 associates with accelerated disease progression in chronic lymphocytic leukemiaBlood201675
Stability-driven nonnegative matrix factorization to interpret spatial gene expression and build local gene networksProceedings of the National Academy of Sciences of the United States of America201673
Chemical and Biophysical Modulation of Cas9 for Tunable Genome EngineeringACS Chemical Biology201672
Unique attributes of cyanobacterial metabolism revealed by improved genome-scale metabolic modeling and essential gene analysisProceedings of the National Academy of Sciences of the United States of America201672