The long noncoding RNA THRIL regulates TNFα expression through its interaction with hnRNPL | Proceedings of the National Academy of Sciences of the United States of America | 2014 | 442 |
An evolutionarily conserved long noncoding RNA TUNA controls pluripotency and neural lineage commitment | Molecular Cell | 2014 | 292 |
Once-weekly albiglutide versus once-daily liraglutide in patients with type 2 diabetes inadequately controlled on oral drugs (HARMONY 7): a randomised, open-label, multicentre, non-inferiority phase 3 study | Lancet Diabetes and Endocrinology,the | 2014 | 249 |
Missense mutations in plakophilin-2 cause sodium current deficit and associate with a Brugada syndrome phenotype | Circulation | 2014 | 242 |
STAT3 signaling controls satellite cell expansion and skeletal muscle repair | Nature Medicine | 2014 | 241 |
Energy metabolic reprogramming in the hypertrophied and early stage failing heart: a multisystems approach | Circulation: Heart Failure | 2014 | 165 |
Etchable plasmonic nanoparticle probes to image and quantify cellular internalization | Nature Materials | 2014 | 131 |
An endocytosis pathway initiated through neuropilin-1 and regulated by nutrient availability | Nature Communications | 2014 | 114 |
FFAS-3D: improving fold recognition by including optimized structural features and template re-ranking | Bioinformatics | 2014 | 83 |
Hsp90 chaperone inhibitor 17-AAG attenuates Aβ-induced synaptic toxicity and memory impairment | Journal of Neuroscience | 2014 | 78 |
Obesity and lipid stress inhibit carnitine acetyltransferase activity | Journal of Lipid Research | 2014 | 65 |
Kinome-wide functional analysis highlights the role of cytoskeletal remodeling in somatic cell reprogramming | Cell Stem Cell | 2014 | 51 |
Sorting nexin 27 regulates Aβ production through modulating γ-secretase activity | Cell Reports | 2014 | 51 |
A free cysteine prolongs the half-life of a homing peptide and improves its tumor-penetrating activity | Journal of Controlled Release | 2014 | 48 |
Efficacy and safety of initial combination therapy with alogliptin plus metformin versus either as monotherapy in drug-naïve patients with type 2 diabetes: a randomized, double-blind, 6-month study | Diabetes, Obesity and Metabolism | 2014 | 46 |
Genome-wide functional analysis reveals factors needed at the transition steps of induced reprogramming | Cell Reports | 2014 | 42 |
A novel approach to maintain gut mucosal integrity using an oral enzyme supplement | Annals of Surgery | 2014 | 37 |
AIDA: ab initio domain assembly server | Nucleic Acids Research | 2014 | 35 |
Phosphorylation of eIF2α is dispensable for differentiation but required at a posttranscriptional level for paneth cell function and intestinal homeostasis in mice | Inflammatory Bowel Diseases | 2014 | 35 |
Metabolic dysfunction consistent with premature aging results from deletion of Pim kinases | Circulation Research | 2014 | 34 |
Deficiency of the sialyltransferase St3Gal4 reduces Ccl5-mediated myeloid cell recruitment and arrest: short communication | Circulation Research | 2014 | 30 |
Human neural stem cells survive long term in the midbrain of dopamine-depleted monkeys after GDNF overexpression and project neurites toward an appropriate target | Stem Cells Translational Medicine | 2014 | 29 |
A balance between B cell receptor and inhibitory receptor signaling controls plasma cell differentiation by maintaining optimal Ets1 levels | Journal of Immunology | 2014 | 27 |
The role of microRNA-15b in the impaired angiogenesis in diabetic wounds | Wound Repair and Regeneration | 2014 | 27 |
Reprogramming human retinal pigmented epithelial cells to neurons using recombinant proteins | Stem Cells Translational Medicine | 2014 | 26 |