Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota | Nature | 2015 | 1.1K |
Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity | Science | 2016 | 929 |
Primary sclerosing cholangitis is characterised by intestinal dysbiosis independent from IBD | Gut | 2016 | 212 |
Protein export through the bacterial Sec pathway | Nature Reviews Microbiology | 2017 | 201 |
Type III Secretion: Building and Operating a Remarkable Nanomachine | Trends in Biochemical Sciences | 2016 | 105 |
The importance of the twin-arginine translocation pathway for bacterial virulence | Trends in Microbiology | 2008 | 87 |
Specific targeting of cytosine deaminase to solid tumors by engineered Clostridium acetobutylicum | Cancer Gene Therapy | 2001 | 84 |
The genome sequence of Streptomyces lividans 66 reveals a novel tRNA-dependent peptide biosynthetic system within a metal-related genomic island | Genome Biology and Evolution | 2013 | 83 |
Characterization of the Streptomyces lividans PspA Response | Journal of Bacteriology | 2009 | 78 |
Staphylococcal biofilm growth on smooth and porous titanium coatings for biomedical applications | Journal of Biomedical Materials Research - Part A | 2014 | 72 |
SecA-mediated targeting and translocation of secretory proteins | Biochimica Et Biophysica Acta - Molecular Cell Research | 2014 | 65 |
Complete genome sequence of Streptomyces lividans TK24 | Journal of Biotechnology | 2015 | 62 |
Vascular targeting of solid tumours: a major 'inverse' volume-response relationship following combretastatin A-4 phosphate treatment of rat rhabdomyosarcomas | European Journal of Cancer | 2000 | 60 |
Protein secretion biotechnology in Gram-positive bacteria with special emphasis on Streptomyces lividans | Biochimica Et Biophysica Acta - Molecular Cell Research | 2014 | 59 |
Legionella pneumophila Philadelphia-1 tatB and tatC affect intracellular replication and biofilm formation | Biochemical and Biophysical Research Communications | 2005 | 59 |
Protein folding in the cell envelope of Escherichia coli | Nature Microbiology | 2016 | 54 |
Spores of Clostridium engineered for clinical efficacy and safety cause regression and cure of tumors in vivo | Oncotarget | 2014 | 53 |
The use of clostridial spores for cancer treatment | Journal of Applied Microbiology | 2006 | 50 |
Secretory production of biologically active rat interleukin-2 by Clostridium acetobutylicum DSM792 as a tool for anti-tumor treatment | FEMS Microbiology Letters | 2005 | 49 |
Preprotein mature domains contain translocase targeting signals that are essential for secretion | Journal of Cell Biology | 2017 | 45 |
Synthesis of novel 5-amino-thiazolo[4,5-d]pyrimidines as E. coli and S. aureus SecA inhibitors | Bioorganic and Medicinal Chemistry | 2011 | 43 |
pspA overexpression in Streptomyces lividans improves both Sec- and Tat-dependent protein secretion | Applied Microbiology and Biotechnology | 2007 | 43 |
Structures of chaperone-substrate complexes docked onto the export gate in a type III secretion system | Nature Communications | 2018 | 41 |
Tumor-specific gene delivery using genetically engineered bacteria | Current Gene Therapy | 2003 | 40 |
A putative twin-arginine translocation pathway in Legionella pneumophila | Biochemical and Biophysical Research Communications | 2004 | 38 |