| Comparison of weight-loss diets with different compositions of fat, protein, and carbohydrates | New England Journal of Medicine | 2009 | 1.4K |
| Effect of structured physical activity on prevention of major mobility disability in older adults: the LIFE study randomized clinical trial | JAMA - Journal of the American Medical Association | 2014 | 804 |
| Mechanisms, Pathophysiology, and Management of Obesity | New England Journal of Medicine | 2017 | 716 |
| Efficacy and safety of canagliflozin monotherapy in subjects with type 2 diabetes mellitus inadequately controlled with diet and exercise | Diabetes, Obesity and Metabolism | 2013 | 460 |
| Leisure-time running reduces all-cause and cardiovascular mortality risk | Journal of the American College of Cardiology | 2014 | 451 |
| Effects of COVID-19 Lockdown on Lifestyle Behaviors in Children with Obesity Living in Verona, Italy: A Longitudinal Study | Obesity | 2020 | 437 |
| Effects on blood lipids of a blood pressure-lowering diet: the Dietary Approaches to Stop Hypertension (DASH) Trial | American Journal of Clinical Nutrition | 2001 | 417 |
| Effects of comprehensive lifestyle modification on diet, weight, physical fitness, and blood pressure control: 18-month results of a randomized trial | Annals of Internal Medicine | 2006 | 415 |
| The role of exercise and physical activity in weight loss and maintenance | Progress in Cardiovascular Diseases | 2014 | 408 |
| Obesity and cardiovascular diseases: implications regarding fitness, fatness, and severity in the obesity paradox | Journal of the American College of Cardiology | 2014 | 382 |
| Effects of diet and sodium intake on blood pressure: subgroup analysis of the DASH-sodium trial | Annals of Internal Medicine | 2001 | 380 |
| Waist and hip circumferences have independent and opposite effects on cardiovascular disease risk factors: the Quebec Family Study | American Journal of Clinical Nutrition | 2001 | 377 |
| Exercise and the cardiovascular system: clinical science and cardiovascular outcomes | Circulation Research | 2015 | 373 |
| Sedentary behaviors increase risk of cardiovascular disease mortality in men | Medicine and Science in Sports and Exercise | 2010 | 329 |
| Impact of obesity and the obesity paradox on prevalence and prognosis in heart failure | JACC: Heart Failure | 2013 | 323 |
| A new proposed guidance system for beverage consumption in the United States | American Journal of Clinical Nutrition | 2006 | 306 |
| Abdominal fat distribution and metabolic risk factors: effects of race | Metabolism: Clinical and Experimental | 1996 | 286 |
| Comparisons of leisure-time physical activity and cardiorespiratory fitness as predictors of all-cause mortality in men and women | British Journal of Sports Medicine | 2011 | 284 |
| Genomic predictors of the maximal O₂ uptake response to standardized exercise training programs | Journal of Applied Physiology | 2011 | 275 |
| Sibutramine produces dose-related weight loss | Obesity | 1999 | 272 |
| Alterations in the dynamics of circulating ghrelin, adiponectin, and leptin in human obesity | Proceedings of the National Academy of Sciences of the United States of America | 2004 | 269 |
| Association Between Hypoxemia and Mortality in Patients With COVID-19 | Mayo Clinic Proceedings | 2020 | 263 |
| A 6-month randomized, placebo-controlled, dose-ranging trial of topiramate for weight loss in obesity | Obesity | 2003 | 256 |
| A 2-Year Randomized Controlled Trial of Human Caloric Restriction: Feasibility and Effects on Predictors of Health Span and Longevity | Journals of Gerontology - Series A Biological Sciences and Medical Sciences | 2015 | 254 |
| Sex differences in obesity and the regulation of energy homeostasis | Obesity Reviews | 2009 | 247 |
