Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index | Nature Genetics | 2010 | 2.3K |
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci | Nature Genetics | 2010 | 1.9K |
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk | Nature Genetics | 2010 | 1.7K |
p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription | Journal of Biological Chemistry | 2010 | 928 |
A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1 | Nature Genetics | 2010 | 773 |
Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls | Nature | 2010 | 639 |
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge | Nature Genetics | 2010 | 527 |
Incidence of amyotrophic lateral sclerosis in Europe | Journal of Neurology, Neurosurgery and Psychiatry | 2010 | 464 |
Cancer chemoprevention mechanisms mediated through the Keap1-Nrf2 pathway | Antioxidants and Redox Signaling | 2010 | 413 |
Quantitative shear wave ultrasound elastography: initial experience in solid breast masses | Breast Cancer Research | 2010 | 325 |
Keap1 perceives stress via three sensors for the endogenous signaling molecules nitric oxide, zinc, and alkenals | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 309 |
Dietary prebiotics: current status and new definition | Food Science and Technology Bulletin | 2010 | 305 |
'Critical view of safety' as an alternative to routine intraoperative cholangiography during laparoscopic cholecystectomy for acute biliary pathology | Journal of Gastrointestinal Surgery | 2010 | 258 |
Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension | PLoS Genetics | 2010 | 255 |
Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction | Nature Genetics | 2010 | 249 |
Phosphorylation of Mcl-1 by CDK1-cyclin B1 initiates its Cdc20-dependent destruction during mitotic arrest | EMBO Journal | 2010 | 244 |
Effect of high-dose allopurinol on exercise in patients with chronic stable angina: a randomised, placebo controlled crossover trial | Lancet, The | 2010 | 243 |
Serum thyroid-stimulating hormone concentration and morbidity from cardiovascular disease and fractures in patients on long-term thyroxine therapy | Journal of Clinical Endocrinology and Metabolism | 2010 | 242 |
Role of the WNK-activated SPAK kinase in regulating blood pressure | EMBO Molecular Medicine | 2010 | 214 |
Internal rotational error of the tibial component is a major cause of pain after total knee replacement | Journal of Bone and Joint Surgery: British Volume | 2010 | 208 |
SPIN (Scottish Pregnancy Intervention) study: a multicenter, randomized controlled trial of low-molecular-weight heparin and low-dose aspirin in women with recurrent miscarriage | Blood | 2010 | 204 |
Prospective comparison of switches in biomarker status between primary and recurrent breast cancer: the Breast Recurrence In Tissues Study (BRITS) | Breast Cancer Research | 2010 | 192 |
Loss of Nrf2 markedly exacerbates nonalcoholic steatohepatitis | Free Radical Biology and Medicine | 2010 | 190 |
Spindle orientation bias in gut epithelial stem cell compartments is lost in precancerous tissue | Cell Stem Cell | 2010 | 189 |
Impact of short-course preoperative radiotherapy for rectal cancer on patients' quality of life: data from the Medical Research Council CR07/National Cancer Institute of Canada Clinical Trials Group C016 randomized clinical trial | Journal of Clinical Oncology | 2010 | 172 |