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Reactive oxygen species (ROS)-induced ROS release: a new phenomenon accompanying induction of the mitochondrial permeability transition in cardiac myocytes | Journal of Experimental Medicine | 2000 | 1.1K |
Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part II: the aging heart in health: links to heart disease | Circulation | 2003 | 866 |
Glycogen synthase kinase-3beta mediates convergence of protection signaling to inhibit the mitochondrial permeability transition pore | Journal of Clinical Investigation | 2004 | 741 |
Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part III: cellular and molecular clues to heart and arterial aging | Circulation | 2003 | 703 |
DNA methylation-based measures of biological age: meta-analysis predicting time to death | Aging | 2016 | 531 |
Selective butyrylcholinesterase inhibition elevates brain acetylcholine, augments learning and lowers Alzheimer beta-amyloid peptide in rodent | Proceedings of the National Academy of Sciences of the United States of America | 2005 | 519 |
A coupled SYSTEM of intracellular Ca2+ clocks and surface membrane voltage clocks controls the timekeeping mechanism of the heart's pacemaker | Circulation Research | 2010 | 418 |
Effects of Intermittent Fasting on Health, Aging, and Disease | New England Journal of Medicine | 2019 | 410 |
Aging-associated cardiovascular changes and their relationship to heart failure | Heart Failure Clinics | 2012 | 367 |
Exenatide once weekly versus placebo in Parkinson's disease: a randomised, double-blind, placebo-controlled trial | Lancet, The | 2017 | 352 |
Metabolic syndrome amplifies the age-associated increases in vascular thickness and stiffness | Journal of the American College of Cardiology | 2004 | 349 |
Calorie restriction mimetics: an emerging research field | Aging Cell | 2006 | 341 |
Pulse pressure and pulse wave velocity are related to cognitive decline in the Baltimore Longitudinal Study of Aging | Hypertension | 2008 | 327 |
Blueberry polyphenols increase lifespan and thermotolerance in Caenorhabditis elegans | Aging Cell | 2006 | 321 |
Senolytic therapy alleviates Aβ-associated oligodendrocyte progenitor cell senescence and cognitive deficits in an Alzheimer's disease model | Nature Neuroscience | 2019 | 315 |
Are sirtuins viable targets for improving healthspan and lifespan? | Nature Reviews Drug Discovery | 2012 | 300 |
Caloric restriction increases neurotrophic factor levels and attenuates neurochemical and behavioral deficits in a primate model of Parkinson's disease | Proceedings of the National Academy of Sciences of the United States of America | 2004 | 283 |
Aging in rhesus monkeys: relevance to human health interventions | Science | 2004 | 272 |
Endogenous nitric oxide mechanisms mediate the stretch dependence of Ca2+ release in cardiomyocytes | Nature Cell Biology | 2001 | 270 |
Longitudinal change in height of men and women: implications for interpretation of the body mass index: the Baltimore Longitudinal Study of Aging | American Journal of Epidemiology | 1999 | 258 |
Menopause accelerates biological aging | Proceedings of the National Academy of Sciences of the United States of America | 2016 | 248 |
Effects of Sex, Strain, and Energy Intake on Hallmarks of Aging in Mice | Cell Metabolism | 2016 | 245 |
Heart rate variability and its relation to prefrontal cognitive function: the effects of training and detraining | European Journal of Applied Physiology | 2004 | 242 |
Activation of distinct cAMP-dependent and cGMP-dependent pathways by nitric oxide in cardiac myocytes | Circulation Research | 1999 | 239 |