The glucose transporter Glut1 is selectively essential for CD4 T cell activation and effector function | Cell Metabolism | 2014 | 621 |
Metabolic reprogramming of macrophages: glucose transporter 1 (GLUT1)-mediated glucose metabolism drives a proinflammatory phenotype | Journal of Biological Chemistry | 2014 | 444 |
Metabolic reprogramming is required for antibody production that is suppressed in anergic but exaggerated in chronically BAFF-exposed B cells | Journal of Immunology | 2014 | 282 |
Energy metabolic reprogramming in the hypertrophied and early stage failing heart: a multisystems approach | Circulation: Heart Failure | 2014 | 165 |
Systematic identification of signaling pathways with potential to confer anticancer drug resistance | Science Signaling | 2014 | 117 |
Copper signaling axis as a target for prostate cancer therapeutics | Cancer Research | 2014 | 94 |
Metabolic reprogramming towards aerobic glycolysis correlates with greater proliferative ability and resistance to metabolic inhibition in CD8 versus CD4 T cells | PLoS ONE | 2014 | 86 |
MFN1 deacetylation activates adaptive mitochondrial fusion and protects metabolically challenged mitochondria | Journal of Cell Science | 2014 | 71 |
Novel bone morphogenetic protein signaling through Smad2 and Smad3 to regulate cancer progression and development | FASEB Journal | 2014 | 68 |
Obesity and lipid stress inhibit carnitine acetyltransferase activity | Journal of Lipid Research | 2014 | 65 |
Dietary intake of palmitate and oleate has broad impact on systemic and tissue lipid profiles in humans | American Journal of Clinical Nutrition | 2014 | 59 |
MED13-dependent signaling from the heart confers leanness by enhancing metabolism in adipose tissue and liver | EMBO Molecular Medicine | 2014 | 59 |
BMI, RQ, diabetes, and sex affect the relationships between amino acids and clamp measures of insulin action in humans | Diabetes | 2014 | 58 |
A rapid cytoplasmic mechanism for PI3 kinase regulation by the nuclear thyroid hormone receptor, TRβ, and genetic evidence for its role in the maturation of mouse hippocampal synapses in vivo | Endocrinology | 2014 | 57 |
Exposure to mitochondrial genotoxins and dopaminergic neurodegeneration in Caenorhabditis elegans | PLoS ONE | 2014 | 47 |
Division of labour between Myc and G1 cyclins in cell cycle commitment and pace control | Nature Communications | 2014 | 45 |
Angiotensin-converting enzyme 2 decreases formation and severity of angiotensin II-induced abdominal aortic aneurysms | Arteriosclerosis, Thrombosis, and Vascular Biology | 2014 | 42 |
Uveal melanoma treated with iodine-125 episcleral plaque: an analysis of dose on disease control and visual outcomes | International Journal of Radiation Oncology Biology Physics | 2014 | 42 |
Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters | ELife | 2014 | 42 |
Downregulation of carnitine acyl-carnitine translocase by miRNAs 132 and 212 amplifies glucose-stimulated insulin secretion | Diabetes | 2014 | 40 |
Current understanding of signal amplification in phototransduction | Cellular Logistics | 2014 | 40 |
Glucose transporter 1-mediated glucose uptake is limiting for B-cell acute lymphoblastic leukemia anabolic metabolism and resistance to apoptosis | Cell Death and Disease | 2014 | 39 |
Targeted metabolomics connects thioredoxin-interacting protein (TXNIP) to mitochondrial fuel selection and regulation of specific oxidoreductase enzymes in skeletal muscle | Journal of Biological Chemistry | 2014 | 39 |
The collagen scaffold with collagen binding BDNF enhances functional recovery by facilitating peripheral nerve infiltrating and ingrowth in canine complete spinal cord transection | Spinal Cord | 2014 | 35 |
Ectodomain shedding of TβRIII is required for TβRIII-mediated suppression of TGF-β signaling and breast cancer migration and invasion | Molecular Biology of the Cell | 2014 | 31 |