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Top Articles

#TitleJournalYearCitations
1Guidelines for the use and interpretation of assays for monitoring autophagyAutophagy20123,158
2Reduced Paneth cell α-defensins in ileal Crohn's diseaseProceedings of the National Academy of Sciences of the United States of America2005962
3Natural Killer Cells: Development, Maturation, and Clinical UtilizationFrontiers in Immunology2018787
4ExoU expression by Pseudomonas aeruginosa correlates with acute cytotoxicity and epithelial injuryMolecular Microbiology1997514
5Dendritic-cell interactions with HIV: infection and viral disseminationNature Reviews Immunology2006483
6Early-onset lymphoproliferation and autoimmunity caused by germline STAT3 gain-of-function mutationsBlood2015453
7Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophagesJournal of Cell Biology2009452
8Type III Protein Secretion Is Associated with Death in Lower Respiratory and SystemicPseudomonas aeruginosaInfectionsJournal of Infectious Diseases2001448
9CD4+ T Cell Help Is Required for the Formation of a Cytolytic CD8+ T Cell Subset that Protects against Chronic Infection and CancerImmunity2019439
10Role for Hydrogen Peroxide in Flow-Induced Dilation of Human Coronary ArteriolesCirculation Research2003396
11The exoenzyme S regulon of Pseudomonas aeruginosaMolecular Microbiology1997369
12Microglial cell activation and proliferation precedes the onset of CNS autoimmunityJournal of Neuroscience Research2005369
13Signal Transduction Pathways Mediated by PECAM-1Arteriosclerosis, Thrombosis, and Vascular Biology2003368
14Bacteriocin production augments niche competition by enterococci in the mammalian gastrointestinal tractNature2015349
15Increasing Incidence of Chronic Graft-versus-Host Disease in Allogeneic Transplantation: A Report from the Center for International Blood and Marrow Transplant ResearchBiology of Blood and Marrow Transplantation2015348
16Active and passive immunization with the Pseudomonas V antigen protects against type III intoxication and lung injuryNature Medicine1999342
17GM-CSF Production by Autoreactive T Cells Is Required for the Activation of Microglial Cells and the Onset of Experimental Autoimmune EncephalomyelitisJournal of Immunology2007342
18Immunoregulatory properties of ISG15, an interferon-induced cytokine.Proceedings of the National Academy of Sciences of the United States of America1996334
19Direct suppression of CNS autoimmune inflammation via the cannabinoid receptor CB1 on neurons and CB2 on autoreactive T cellsNature Medicine2007334
20The mechanism of action of the Pseudomonas aeruginosa-encoded type III cytotoxin, ExoUEMBO Journal2003323
21Initiating DNA synthesis: from recruiting to activating the MCM complexJournal of Cell Science2001298
22Development of primary human pancreatic cancer organoids, matched stromal and immune cells and 3D tumor microenvironment modelsBMC Cancer2018289
23B Cell Regulation of CD4+CD25+ T Regulatory Cells and IL-10 Via B7 is Essential for Recovery From Experimental Autoimmune EncephalomyelitisJournal of Immunology2007285
24Branhamella catarrhalis: an organism gaining respect as a pathogenClinical Microbiology Reviews1990283
25Immune-checkpoint proteins VISTA and PD-1 nonredundantly regulate murine T-cell responsesProceedings of the National Academy of Sciences of the United States of America2015283
26Exoenzyme S of Pseudomonas aeruginosa is secreted by a type III pathwayMolecular Microbiology1996280
27Leptospira as an Emerging Pathogen: A Review of its Biology, Pathogenesis and Host Immune ResponsesFuture Microbiology2010267
28Blockade of interleukin-6 signaling augments regulatory T-cell reconstitution and attenuates the severity of graft-versus-host diseaseBlood2009259
29A unique set of polypeptides is induced by γ interferon in addition to those induced in common with α and β interferonsNature1983257
30Prolonged Impact of Antibiotics on Intestinal Microbial Ecology and Susceptibility to Enteric Salmonella InfectionInfection and Immunity2009256
31ExoU is a potent intracellular phospholipaseMolecular Microbiology2004255
32A Novel IL-10–Independent Regulatory Role for B Cells in Suppressing Autoimmunity by Maintenance of Regulatory T Cells via GITR LigandJournal of Immunology2012241
33Use of the Galleria mellonella Caterpillar as a Model Host To Study the Role of the Type III Secretion System in Pseudomonas aeruginosa PathogenesisInfection and Immunity2003237
34The balance between protective and pathogenic immune responses in the TB-infected lungNature Immunology2015232
35The Vaccinia-related Kinases Phosphorylate the N′ Terminus of BAF, Regulating Its Interaction with DNA and Its Retention in the NucleusMolecular Biology of the Cell2006224
36Successful transfusion of platelets “mismatched” for HLA antigens to alloimmunized thrombocytopenic patientsAmerican Journal of Hematology1977223
37Identification of type III secreted products of the Pseudomonas aeruginosa exoenzyme S regulonJournal of Bacteriology1997217
38Bacterial cytotoxins: targeting eukaryotic switchesNature Reviews Microbiology2005214
39Fecal Microbial Transplant Capsules Are Safe in Hepatic Encephalopathy: A Phase 1, Randomized, Placebo‐Controlled TrialHepatology2019214
40Heterogeneity of human bone marrow and blood natural killer cells defined by single-cell transcriptomeNature Communications2019209
41STAT5 Protein Negatively Regulates T Follicular Helper (Tfh) Cell Generation and FunctionJournal of Biological Chemistry2012202
42Gardnerella vaginalis: characteristics, clinical considerations, and controversiesClinical Microbiology Reviews1992199
43Novel bacterial ADP-ribosylating toxins: structure and functionNature Reviews Microbiology2014198
44Pseudomonas aeruginosa ExoS and ExoT2004197
45VISTA Is a Novel Broad-Spectrum Negative Checkpoint Regulator for Cancer ImmunotherapyCancer Immunology Research2014193
46In vitro and in vivo secretion of human ISG15, an IFN-induced immunomodulatory cytokine.Journal of Immunology1996188
47Platelet PECAM-1 inhibits thrombus formation in vivoBlood2006186
48HIV interactions with monocytes and dendritic cells: viral latency and reservoirsRetrovirology2009185
49Structural elements required for the localization of ASH1 mRNA and of a green fluorescent protein reporter particle in vivoCurrent Biology1999184
50Monomeric and dimeric CXCL12 inhibit metastasis through distinct CXCR4 interactions and signaling pathwaysProceedings of the National Academy of Sciences of the United States of America2011183