# | Title | Journal | Year | Citations |
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1 | The menthol receptor TRPM8 is the principal detector of environmental cold | Nature | 2007 | 1,151 |
2 | Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cells | Hepatology | 2010 | 1,100 |
3 | Organogenesis and Development of the Liver | Developmental Cell | 2010 | 666 |
4 | Piezo2 is required for Merkel-cell mechanotransduction | Nature | 2014 | 623 |
5 | Hepatocyte nuclear factor 4α controls the development of a hepatic epithelium and liver morphogenesis | Nature Genetics | 2003 | 541 |
6 | Photobiomodulation Directly Benefits Primary Neurons Functionally Inactivated by Toxins | Journal of Biological Chemistry | 2005 | 514 |
7 | Inhibition of prostate cancer proliferation by interference with SONIC HEDGEHOG-GLI1 signaling | Proceedings of the National Academy of Sciences of the United States of America | 2004 | 478 |
8 | The intraflagellar transport protein, IFT88, is essential for vertebrate photoreceptor assembly and maintenance | Journal of Cell Biology | 2002 | 446 |
9 | The orphan nuclear receptor HNF4α determines PXR- and CAR-mediated xenobiotic induction of CYP3A4 | Nature Medicine | 2003 | 421 |
10 | Chronic hyperalgesia induced by repeated acid injections in muscle is abolished by the loss of ASIC3, but not ASIC1 | Pain | 2003 | 400 |
11 | Cardiac-Specific Deletion of Gata4 Reveals Its Requirement for Hypertrophy, Compensation, and Myocyte Viability | Circulation Research | 2006 | 390 |
12 | Pluripotent neural crest stem cells in the adult hair follicle | Developmental Dynamics | 2004 | 365 |
13 | Energy metabolism of the visual system | Eye and Brain | 2010 | 358 |
14 | Therapeutic photobiomodulation for methanol-induced retinal toxicity | Proceedings of the National Academy of Sciences of the United States of America | 2003 | 353 |
15 | Role of prostaglandin E2-dependent angiogenic switch in cyclooxygenase 2-induced breast cancer progression | Proceedings of the National Academy of Sciences of the United States of America | 2004 | 345 |
16 | The 5-HT3Subtype of Serotonin Receptor Contributes to Nociceptive Processing via a Novel Subset of Myelinated and Unmyelinated Nociceptors | Journal of Neuroscience | 2002 | 344 |
17 | TRUPATH, an open-source biosensor platform for interrogating the GPCR transducerome | Nature Chemical Biology | 2020 | 339 |
18 | A Comparison of Visual and Auditory Motion Processing in Human Cerebral Cortex | Cerebral Cortex | 2000 | 332 |
19 | Crosstalk between B lymphocytes, microbiota and the intestinal epithelium governs immunity versus metabolism in the gut | Nature Medicine | 2011 | 328 |
20 | Clinical and Experimental Applications of NIR-LED Photobiomodulation | Photomedicine and Laser Surgery | 2006 | 327 |
21 | In Vivo Imaging of Human Cone Photoreceptor Inner Segments | | 2014 | 325 |
22 | GATA4 is essential for formation of the proepicardium and regulates cardiogenesis | Proceedings of the National Academy of Sciences of the United States of America | 2004 | 322 |
23 | Noninvasive imaging of the human rod photoreceptor mosaic using a confocal adaptive optics scanning ophthalmoscope | Biomedical Optics Express | 2011 | 315 |
24 | Regulation of Neurogenesis by Interkinetic Nuclear Migration through an Apical-Basal Notch Gradient | Cell | 2008 | 291 |
25 | Embryonic development of the liver | Hepatology | 2005 | 279 |
26 | A non-hallucinogenic psychedelic analogue with therapeutic potential | Nature | 2021 | 262 |
27 | Epigenetic targeting of Hedgehog pathway transcriptional output through BET bromodomain inhibition | Nature Medicine | 2014 | 261 |
28 | Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain | Nature | 2016 | 255 |
29 | Biology of tissue factor pathway inhibitor | Blood | 2014 | 248 |
30 | YAP is essential for tissue tension to ensure vertebrate 3D body shape | Nature | 2015 | 248 |
31 | HNF4: A central regulator of hepatocyte differentiation and function | Hepatology | 2003 | 247 |
32 | Actomyosin Is the Main Driver of Interkinetic Nuclear Migration in the Retina | Cell | 2009 | 238 |
33 | Identification of small molecules for human hepatocyte expansion and iPS differentiation | Nature Chemical Biology | 2013 | 234 |
34 | Local cellular sources of apolipoprotein E in the human retina and retinal pigmented epithelium: implications for the process of drusen formation | American Journal of Ophthalmology | 2001 | 232 |
35 | Hepatocyte nuclear factor 4α orchestrates expression of cell adhesion proteins during the epithelial transformation of the developing liver | Proceedings of the National Academy of Sciences of the United States of America | 2006 | 227 |
36 | GATA6 Is Essential for Embryonic Development of the Liver but Dispensable for Early Heart Formation | Molecular and Cellular Biology | 2005 | 220 |
37 | Endoderm and heart development | Developmental Dynamics | 2000 | 212 |
38 | Virtual discovery of melatonin receptor ligands to modulate circadian rhythms | Nature | 2020 | 210 |
39 | Heterogeneity of human bone marrow and blood natural killer cells defined by single-cell transcriptome | Nature Communications | 2019 | 209 |
40 | Functional consequences of the relative numbers of L and M cones | Journal of the Optical Society of America A: Optics and Image Science, and Vision | 2000 | 206 |
41 | Loss of Nocturnin, a circadian deadenylase, confers resistance to hepatic steatosis and diet-induced obesity | Proceedings of the National Academy of Sciences of the United States of America | 2007 | 200 |
42 | Modeling hepatitis C virus infection using human induced pluripotent stem cells | Proceedings of the National Academy of Sciences of the United States of America | 2012 | 199 |
43 | Progression of HCC in mice is associated with a downregulation in the expression of hepatocyte nuclear factors | Hepatology | 2004 | 195 |
44 | Generation of human induced pluripotent stem cells by simple transient transfection of plasmid DNA encoding reprogramming factors | BMC Developmental Biology | 2010 | 194 |
45 | Iron deficiency in blood donors: the REDS‐II Donor Iron Status Evaluation (RISE) study | Transfusion | 2012 | 194 |
46 | Loss of both GATA4 and GATA6 blocks cardiac myocyte differentiation and results in acardia in mice | Developmental Biology | 2008 | 193 |
47 | HNF4A is essential for specification of hepatic progenitors from human pluripotent stem cells | Development (Cambridge) | 2011 | 185 |
48 | A threshold of GATA4 and GATA6 expression is required for cardiovascular development | Proceedings of the National Academy of Sciences of the United States of America | 2006 | 179 |
49 | The transcription factor cyclic AMP–responsive element–binding protein H regulates triglyceride metabolism | Nature Medicine | 2011 | 176 |
50 | Ethnicity, sex, and age are determinants of red blood cell storage and stress hemolysis: results of the REDS-III RBC-Omics study | Blood Advances | 2017 | 175 |