Frequent and focal FGFR1 amplification associates with therapeutically tractable FGFR1 dependency in squamous cell lung cancer | Science Translational Medicine | 2010 | 646 |
Phase 1 Trials of rVSV Ebola Vaccine in Africa and Europe | New England Journal of Medicine | 2016 | 282 |
Deletion of Kv4.2 gene eliminates dendritic A-type K+ current and enhances induction of long-term potentiation in hippocampal CA1 pyramidal neurons | Journal of Neuroscience | 2006 | 252 |
Outsourcing in the brain: do neurons depend on cholesterol delivery by astrocytes? | BioEssays | 2003 | 230 |
A complete genetic analysis of neuronal Rab3 function | Journal of Neuroscience | 2004 | 213 |
Bronchial and peripheral murine lung carcinomas induced by T790M-L858R mutant EGFR respond to HKI-272 and rapamycin combination therapy | Cancer Cell | 2007 | 193 |
Loss of FFA2 and FFA3 increases insulin secretion and improves glucose tolerance in type 2 diabetes | Nature Medicine | 2015 | 188 |
Progression of myocardial necrosis during reperfusion of ischemic myocardium | Circulation | 1998 | 187 |
Intravascular Survival and Extravasation of Tumor Cells | Cancer Cell | 2017 | 181 |
The retinoblastoma protein: a master regulator of cell cycle, differentiation and apoptosis | FEBS Journal | 1997 | 178 |
Semaphorins and plexins as therapeutic targets | Nature Reviews Drug Discovery | 2014 | 177 |
LITTLE FISH, BIG DATA: ZEBRAFISH AS A MODEL FOR CARDIOVASCULAR AND METABOLIC DISEASE | Physiological Reviews | 2017 | 174 |
Insights into ALK-driven cancers revealed through development of novel ALK tyrosine kinase inhibitors | Cancer Research | 2011 | 174 |
The metallochaperone Atox1 plays a critical role in perinatal copper homeostasis | Proceedings of the National Academy of Sciences of the United States of America | 2001 | 168 |
Ion conduction through C-type inactivated Shaker channels | Journal of General Physiology | 1997 | 163 |
Mice lacking desmocollin 1 show epidermal fragility accompanied by barrier defects and abnormal differentiation | Journal of Cell Biology | 2001 | 161 |
Laminar shear stress inhibits endothelial cell metabolism via KLF2-mediated repression of PFKFB3 | Arteriosclerosis, Thrombosis, and Vascular Biology | 2015 | 160 |
Redirecting tumor-associated macrophages to become tumoricidal effectors as a novel strategy for cancer therapy | Oncotarget | 2017 | 153 |
Heat shock protein 70 is required for the survival of cancer cells | Annals of the New York Academy of Sciences | 2000 | 152 |
Bystander killing of malignant glioma by bone marrow-derived tumor-infiltrating progenitor cells expressing a suicide gene | Molecular Therapy | 2007 | 134 |
Targeted Ablation of Periostin-Expressing Activated Fibroblasts Prevents Adverse Cardiac Remodeling in Mice | Circulation Research | 2016 | 133 |
Hunger-Driven Motivational State Competition | Neuron | 2016 | 131 |
Sca1-derived cells are a source of myocardial renewal in the murine adult heart | Stem Cell Reports | 2013 | 123 |
Phosphorylation site-specific inhibition of platelet-derived growth factor beta-receptor autophosphorylation by the receptor blocking tyrphostin AG1296 | Biochemistry | 1997 | 123 |
Functional interactions of genes mediating convergent extension, knypek and trilobite, during the partitioning of the eye primordium in zebrafish | Developmental Biology | 1998 | 123 |