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Top Articles

#TitleJournalYearCitations
1METTL3-mediated m6A modification of HDGF mRNA promotes gastric cancer progression and has prognostic significanceGut2020715
2Endoplasmic Reticulum Stress Causes Liver Cancer Cells to Release Exosomal miR‐23a‐3p and Up‐regulate Programmed Death Ligand 1 Expression in MacrophagesHepatology2019417
3Acquired CDK6 amplification promotes breast cancer resistance to CDK4/6 inhibitors and loss of ER signaling and dependenceOncogene2016377
4The Chinese Society of Clinical Oncology (CSCO) clinical guidelines for the diagnosis and treatment of nasopharyngeal carcinomaCancer Communications2021335
5Bacteria Detection: From Powerful SERS to Its Advanced Compatible TechniquesAdvanced Science2020270
6Mitochondrion‐Anchoring Photosensitizer with Aggregation‐Induced Emission Characteristics Synergistically Boosts the Radiosensitivity of Cancer Cells to Ionizing RadiationAdvanced Materials2017256
7Alterations in the human oral and gut microbiomes and lipidomics in COVID-19Gut2021239
8A Hollow Amorphous Bimetal Organic Framework for Synergistic Cuproptosis/Ferroptosis/Apoptosis Anticancer Therapy via Disrupting Intracellular Redox Homeostasis and Copper/Iron MetabolismsAdvanced Functional Materials2022228
9Zinc attenuates ferroptosis and promotes functional recovery in contusion spinal cord injury by activating Nrf2/GPX4 defense pathwayCNS Neuroscience and Therapeutics2021224
10Patient-derived human tumour tissue xenografts in immunodeficient mice: a systematic reviewClinical and Translational Oncology2010200
11Revealing the transcriptional heterogeneity of organ‐specific metastasis in human gastric cancer using single‐cell RNA SequencingClinical and Translational Medicine2022195
12Increased expression of programmed death (PD)‐1 and its ligand PD‐L1 correlates with impaired cell‐mediated immunity in high‐risk human papillomavirus‐related cervical intraepithelial neoplasiaImmunology2013191
13Myeloid‐Cell–Specific IL‐6 Signaling Promotes MicroRNA‐223‐Enriched Exosome Production to Attenuate NAFLD‐Associated FibrosisHepatology2021189
14Metabolic reprogramming in cancer: Mechanisms and therapeuticsMedComm2023184
15Cancer-cell-secreted CXCL11 promoted CD8+ T cells infiltration through docetaxel-induced-release of HMGB1 in NSCLC2019182
16Regenerative proliferation of differentiated cells by mTORC 1‐dependent paligenosisEMBO Journal2018180
17N6‐Methyladenosine Reader Protein YT521‐B Homology Domain‐Containing 2 Suppresses Liver Steatosis by Regulation of mRNA Stability of Lipogenic GenesHepatology2021178
18Applying amide proton transfer‐weighted MRI to distinguish pseudoprogression from true progression in malignant gliomasJournal of Magnetic Resonance Imaging2016169
19Attractive Pickering Emulsion GelsAdvanced Materials2021167
20LncRNA‐MALAT1 Promotes Angiogenesis of Thyroid Cancer by Modulating Tumor‐Associated Macrophage FGF2 Protein SecretionJournal of Cellular Biochemistry2017164
21IL‐10 derived from M2 macrophage promotes cancer stemness via JAK1/STAT1/NF‐κB/Notch1 pathway in non‐small cell lung cancerInternational Journal of Cancer2019163
22Efficacy and safety of a novel anti‐HER2 therapeutic antibody RC48 in patients with HER2‐overexpressing, locally advanced or metastatic gastric or gastroesophageal junction cancer: a single‐arm phase II studyCancer Communications2021163
23Oral Hydrogel Microbeads-Mediated In Situ Synthesis of Selenoproteins for Regulating Intestinal Immunity and MicrobiotaJournal of the American Chemical Society2023158
24Camrelizumab plus gemcitabine and oxaliplatin (GEMOX) in patients with advanced biliary tract cancer: a single-arm, open-label, phase II trial2020150
25MicroRNA‐155‐5p promotes hepatocellular carcinoma progression by suppressing PTEN through the PI3K/Akt pathwayCancer Science2017146
26MicroRNAs and cancer stem cells: the sword and the shieldOncogene2013140
27Exosomes from human‐bone‐marrow‐derived mesenchymal stem cells protect against renal ischemia/reperfusion injury via transferring miR‐199a‐3pJournal of Cellular Physiology2019140
28Assessment of ovarian cancer conditions from exhaled breathInternational Journal of Cancer2015134
29Sensitive Detection of Carcinoembryonic Antigen Using Stability‐Limited Few‐Layer Black Phosphorus as an Electron Donor and a ReservoirSmall2017134
30Eliminating METTL1‐mediated accumulation of PMN‐MDSCs prevents hepatocellular carcinoma recurrence after radiofrequency ablationHepatology2023134
31Allogenic Vγ9Vδ2 T cell as new potential immunotherapy drug for solid tumor: a case study for cholangiocarcinoma2019118
32Insufficient Radiofrequency Ablation Promotes Hepatocellular Carcinoma Metastasis Through N6‐Methyladenosine mRNA Methylation‐Dependent MechanismHepatology2021117
33miR-574-5p negatively regulatesQki6/7to impactβ-catenin/Wnt signalling and the development of colorectal cancerGut2013116
34Copper homeostasis and cuproptosis in cancer immunity and therapyImmunological Reviews2024114
35Impaired lipid biosynthesis hinders anti-tumor efficacy of intratumoral iNKT cellsNature Communications2020110
363D‐Printed Biomimetic Systems with Synergetic Color and Shape Responses Based on Oblate Cholesteric Liquid Crystal DropletsAdvanced Materials2021110
37Suppression of Sclerostin Alleviates Radiation-Induced Bone Loss by Protecting Bone-Forming Cells and Their Progenitors Through Distinct MechanismsJournal of Bone and Mineral Research2017107
38PBMC transcriptomics identifies immune-metabolism disorder during the development of HBV-ACLFGut2022107
39Alterations in the gut microbiota and metabolite profiles of thyroid carcinoma patientsInternational Journal of Cancer2019104
40High-affinity neoantigens correlate with better prognosis and trigger potent antihepatocellular carcinoma (HCC) activity by activating CD39+CD8+ T cellsGut2021104
41Microwave ablation versus laparoscopic resection as first‐line therapy for solitary 3–5‐cm HCCHepatology2022104
42Health‐related quality of life of COVID‐19 patients after discharge: A multicenter follow‐up studyJournal of Clinical Nursing2021101
43Methyltransferase like 3 promotes colorectal cancer proliferation by stabilizing CCNE1 mRNA in an m6A‐dependent mannerJournal of Cellular and Molecular Medicine2020100
44Thymoquinone inhibits the metastasis of renal cell cancer cells by inducing autophagy via AMPK/mTOR signaling pathwayCancer Science201893
45KIAA1429 regulates cell proliferation by targeting c‐Jun messenger RNA directly in gastric cancerJournal of Cellular Physiology202093
46LncRNA DANCR promotes cervical cancer progression by upregulating ROCK1 via sponging miR‐335‐5pJournal of Cellular Physiology201992
47CXCR6 is required for antitumor efficacy of intratumoral CD8+T cell202192
48Relmacabtagene autoleucel (relma‐cel) CD19 CAR‐T therapy for adults with heavily pretreated relapsed/refractory large B‐cell lymphoma in ChinaCancer Medicine202192
49Periostin promotes immunosuppressive premetastatic niche formation to facilitate breast tumour metastasisJournal of Pathology201690
50Prediction of central compartment lymph node metastasis in papillary thyroid microcarcinomaClinical Endocrinology201489