| # | Title | Journal | Year | Citations |
|---|
|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,158 |
| 2 | Prevalence of diabetes recorded in mainland China using 2018 diagnostic criteria from the American Diabetes Association: national cross sectional study | BMJ, The | 2020 | 907 |
| 3 | Diabetes as a risk factor for dementia and mild cognitive impairment: a meta‐analysis of longitudinal studies | Internal Medicine Journal | 2012 | 825 |
| 4 | Effect of Iodine Intake on Thyroid Diseases in China | New England Journal of Medicine | 2006 | 637 |
| 5 | Plasma exosomal α-synuclein is likely CNS-derived and increased in Parkinson’s disease | Acta Neuropathologica | 2014 | 535 |
| 6 | Endothelial Dysfunction in Atherosclerotic Cardiovascular Diseases and Beyond: From Mechanism to Pharmacotherapies | Pharmacological Reviews | 2021 | 462 |
| 7 | Standards of medical care for type 2 diabetes in China 2019 | Diabetes/Metabolism Research and Reviews | 2019 | 446 |
| 8 | Prevalence of Hyperuricemia and Gout in Mainland China from 2000 to 2014: A Systematic Review and Meta-Analysis | BioMed Research International | 2015 | 422 |
| 9 | COVID-19 and Liver Dysfunction: Current Insights and Emergent Therapeutic Strategies | Journal of Clinical and Translational Hepatology | 2020 | 340 |
| 10 | A translational study of circulating cell-free microRNA-1 in acute myocardial infarction | Clinical Science | 2010 | 306 |
| 11 | Vitamin D alleviates lipopolysaccharide-induced acute lung injury via regulation of the renin-angiotensin system | Molecular Medicine Reports | 2017 | 304 |
| 12 | Letter to the Editor: Obesity as a risk factor for greater severity of COVID-19 in patients with metabolic associated fatty liver disease | Metabolism: Clinical and Experimental | 2020 | 285 |
| 13 | A machine learning-based framework to identify type 2 diabetes through electronic health records | International Journal of Medical Informatics | 2017 | 271 |
| 14 | TERTPromoter Mutations and Their Association withBRAFV600E Mutation and Aggressive Clinicopathological Characteristics of Thyroid Cancer | Journal of Clinical Endocrinology and Metabolism | 2014 | 268 |
| 15 | Standards of care for type 2 diabetes in China | Diabetes/Metabolism Research and Reviews | 2016 | 244 |
| 16 | Gut microbiota as a potential target of metabolic syndrome: the role of probiotics and prebiotics | Cell and Bioscience | 2017 | 235 |
| 17 | Iodine Status and Prevalence of Thyroid Disorders After Introduction of Mandatory Universal Salt Iodization for 16 Years in China: A Cross-Sectional Study in 10 Cities | Thyroid | 2016 | 232 |
| 18 | LncRNA RPPH1 promotes colorectal cancer metastasis by interacting with TUBB3 and by promoting exosomes-mediated macrophage M2 polarization | Cell Death and Disease | 2019 | 231 |
| 19 | Prevalence of Osteoporosis and Fracture in China | JAMA Network Open | 2021 | 230 |
| 20 | Thyroid Function Analysis in 50 Patients with COVID-19: A Retrospective Study | Thyroid | 2021 | 227 |
| 21 | Effects of Moderate and Vigorous Exercise on Nonalcoholic Fatty Liver Disease | JAMA Internal Medicine | 2016 | 222 |
| 22 | Circulating MicroRNA Profiles as Potential Biomarkers for Diagnosis of Papillary Thyroid Carcinoma | Journal of Clinical Endocrinology and Metabolism | 2012 | 211 |
| 23 | The Prevalence of Osteoporosis in China, a Nationwide, Multicenter DXA Survey | Journal of Bone and Mineral Research | 2019 | 210 |
| 24 | Effect of LPS on the permeability of the blood–brain barrier to insulin | Brain Research | 2001 | 207 |
| 25 | Efficacy and Safety of Long-Term Universal Salt Iodization on Thyroid Disorders: Epidemiological Evidence from 31 Provinces of Mainland China | Thyroid | 2020 | 205 |
| 26 | Single-cell analysis of two severe COVID-19 patients reveals a monocyte-associated and tocilizumab-responding cytokine storm | Nature Communications | 2020 | 194 |
| 27 | Cabozantinib Suppresses Tumor Growth and Metastasis in Hepatocellular Carcinoma by a Dual Blockade of VEGFR2 and MET | Clinical Cancer Research | 2014 | 191 |
| 28 | Association of High Iodine Intake with the T1799A BRAF Mutation in Papillary Thyroid Cancer | Journal of Clinical Endocrinology and Metabolism | 2009 | 190 |
| 29 | Metformin alleviates oxidative stress and enhances autophagy in diabetic kidney disease via AMPK/SIRT1-FoxO1 pathway | Molecular and Cellular Endocrinology | 2020 | 189 |
| 30 | LncRNA HOTTIP modulates cancer stem cell properties in human pancreatic cancer by regulating HOXA9 | Cancer Letters | 2017 | 166 |
| 31 | Colocalization of corticotropin-releasing hormone and oestrogen receptor-α in the paraventricular nucleus of the hypothalamus in mood disorders | Brain | 2005 | 164 |
| 32 | Crosstalk between ER stress, NLRP3 inflammasome, and inflammation | Applied Microbiology and Biotechnology | 2020 | 164 |
| 33 | Resveratrol protects against spinal cord injury by activating autophagy and inhibiting apoptosis mediated by the SIRT1/AMPK signaling pathway | Neuroscience | 2017 | 163 |
| 34 | AMSC-derived exosomes alleviate lipopolysaccharide/d-galactosamine-induced acute liver failure by miR-17-mediated reduction of TXNIP/NLRP3 inflammasome activation in macrophages | EBioMedicine | 2018 | 163 |
| 35 | Subclinical Hypothyroidism and Type 2 Diabetes: A Systematic Review and Meta-Analysis | PLoS ONE | 2015 | 160 |
| 36 | Deep learning-based artificial intelligence model to assist thyroid nodule diagnosis and management: a multicentre diagnostic study | The Lancet Digital Health | 2021 | 160 |
| 37 | Endothelial dysfunction in COVID-19: an overview of evidence, biomarkers, mechanisms and potential therapies | Acta Pharmacologica Sinica | 2023 | 159 |
| 38 | The Role of Autophagy and Mitophagy in Bone Metabolic Disorders | International Journal of Biological Sciences | 2020 | 158 |
| 39 | Osteoarthritis and the risk of cardiovascular disease: a meta-analysis of observational studies | Scientific Reports | 2016 | 157 |
| 40 | Recent advances in understanding the biochemical and molecular mechanism of diabetic retinopathy | Biomedicine and Pharmacotherapy | 2015 | 156 |
| 41 | Celastrol Attenuates Angiotensin II–Induced Cardiac Remodeling by Targeting STAT3 | Circulation Research | 2020 | 151 |
| 42 | Genistein inhibits MDA-MB-231 triple-negative breast cancer cell growth by inhibiting NF-κB activity via the Notch-1 pathway | International Journal of Molecular Medicine | 2012 | 148 |
| 43 | m6A-related lncRNAs are potential biomarkers for predicting prognoses and immune responses in patients with LUAD | Molecular Therapy - Nucleic Acids | 2021 | 147 |
| 44 | Anti-inflammatory effect of resveratrol on TNF-α-induced MCP-1 expression in adipocytes | Biochemical and Biophysical Research Communications | 2008 | 144 |
| 45 | Whole exome sequencing of insulinoma reveals recurrent T372R mutations in YY1 | Nature Communications | 2013 | 144 |
| 46 | Antithyroperoxidase and Antithyroglobulin Antibodies in a Five-Year Follow-Up Survey of Populations with Different Iodine Intakes | Journal of Clinical Endocrinology and Metabolism | 2008 | 143 |
| 47 | N6‐Methyladenosine Reader Protein YT521‐B Homology Domain‐Containing 2 Suppresses Liver Steatosis by Regulation of mRNA Stability of Lipogenic Genes | Hepatology | 2021 | 143 |
| 48 | Extrapulmonary complications of COVID‐19: A multisystem disease? | Journal of Medical Virology | 2021 | 141 |
| 49 | Cytomegalovirus Infection and Relative Risk of Cardiovascular Disease (Ischemic Heart Disease, Stroke, and Cardiovascular Death): A Meta‐Analysis of Prospective Studies Up to 2016 | Journal of the American Heart Association | 2017 | 139 |
| 50 | Sp1 is upregulated in human glioma, promotes MMP‐2‐mediated cell invasion and predicts poor clinical outcome | International Journal of Cancer | 2012 | 138 |
