Imaging atherosclerotic plaque inflammation with [18F]-fluorodeoxyglucose positron emission tomography | Circulation | 2002 | 1K |
Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using 1H-NMR-based metabonomics | Nature Medicine | 2002 | 855 |
Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy | Human Molecular Genetics | 2002 | 828 |
Epistasis: what it means, what it doesn't mean, and statistical methods to detect it in humans | Human Molecular Genetics | 2002 | 725 |
Primary pulmonary hypertension is associated with reduced pulmonary vascular expression of type II bone morphogenetic protein receptor | Circulation | 2002 | 498 |
Induction of adipocyte complement-related protein of 30 kilodaltons by PPARgamma agonists: a potential mechanism of insulin sensitization | Endocrinology | 2002 | 488 |
Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency | Journal of Clinical Investigation | 2002 | 441 |
Prospective study of C-reactive protein in relation to the development of diabetes and metabolic syndrome in the Mexico City Diabetes Study | Diabetes Care | 2002 | 395 |
Heat shock protein 27 prevents cellular polyglutamine toxicity and suppresses the increase of reactive oxygen species caused by huntingtin | Human Molecular Genetics | 2002 | 373 |
Influence of leptin on arterial distensibility: a novel link between obesity and cardiovascular disease? | Circulation | 2002 | 315 |
Slowed conduction and ventricular tachycardia after targeted disruption of the cardiac sodium channel gene Scn5a | Proceedings of the National Academy of Sciences of the United States of America | 2002 | 314 |
Molecular and cellular basis of pulmonary vascular remodeling in pulmonary hypertension | Progress in Cardiovascular Diseases | 2002 | 260 |
ET(A) and ET(B) receptors modulate the proliferation of human pulmonary artery smooth muscle cells | American Journal of Respiratory and Critical Care Medicine | 2002 | 253 |
Current methods of transfer of young people with Type 1 diabetes to adult services | Diabetic Medicine | 2002 | 252 |
Lessons from animal models of Huntington's disease | Trends in Genetics | 2002 | 248 |
Inherited interleukin-12 deficiency: IL12B genotype and clinical phenotype of 13 patients from six kindreds | American Journal of Human Genetics | 2002 | 229 |
A missense mutation disrupting a dibasic prohormone processing site in pro-opiomelanocortin (POMC) increases susceptibility to early-onset obesity through a novel molecular mechanism | Human Molecular Genetics | 2002 | 209 |
Myosin VI binds to and localises with Dab2, potentially linking receptor-mediated endocytosis and the actin cytoskeleton | Traffic | 2002 | 200 |
The effects of tryptophan depletion on cognitive and affective processing in healthy volunteers | Psychopharmacology | 2002 | 194 |
Early nutrition and leptin concentrations in later life | American Journal of Clinical Nutrition | 2002 | 177 |
Glycogen synthase kinase-3beta inhibitors prevent cellular polyglutamine toxicity caused by the Huntington's disease mutation | Journal of Biological Chemistry | 2002 | 164 |
The Nesprins Are Giant Actin-Binding Proteins, Orthologous to Drosophila melanogaster Muscle Protein MSP-300 | Genomics | 2002 | 162 |
Ubiquitylation of MHC class I by the K3 viral protein signals internalization and TSG101-dependent degradation | EMBO Journal | 2002 | 160 |
Isomer-dependent metabolic effects of conjugated linoleic acid: insights from molecular markers sterol regulatory element-binding protein-1c and LXRalpha | Diabetes | 2002 | 153 |
Retardation of post-natal development caused by a negatively acting thyroid hormone receptor alpha1 | EMBO Journal | 2002 | 143 |