| # | Title | Journal | Year | Citations |
|---|
|
| 1 | EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy | Science | 2004 | 9,112 |
| 2 | Computational Radiomics System to Decode the Radiographic Phenotype | Cancer Research | 2017 | 3,880 |
| 3 | Decoding tumour phenotype by noninvasive imaging using a quantitative radiomics approach | Nature Communications | 2014 | 3,501 |
| 4 | Endothelial Cell Dysfunction and the Pathobiology of Atherosclerosis | Circulation Research | 2016 | 2,310 |
| 5 | The evaluation of tumor-infiltrating lymphocytes (TILs) in breast cancer: recommendations by an International TILs Working Group 2014 | Annals of Oncology | 2015 | 2,255 |
| 6 | The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions | Journal of Experimental Medicine | 2007 | 1,999 |
| 7 | Copper induces cell death by targeting lipoylated TCA cycle proteins | Science | 2022 | 1,972 |
| 8 | Adipose Tissue, Inflammation, and Cardiovascular Disease | Circulation Research | 2005 | 1,795 |
| 9 | Induction of angiogenesis during the transition from hyperplasia to neoplasia | Nature | 1989 | 1,793 |
| 10 | Impaired Degradation of Mutant α-Synuclein by Chaperone-Mediated Autophagy | Science | 2004 | 1,786 |
| 11 | DNA Replication in Eukaryotic Cells | Annual Review of Biochemistry | 2002 | 1,604 |
| 12 | Mutations in the Epidermal Growth Factor Receptor and in KRAS Are Predictive and Prognostic Indicators in Patients With Non–Small-Cell Lung Cancer Treated With Chemotherapy Alone and in Combination With Erlotinib | Journal of Clinical Oncology | 2005 | 1,409 |
| 13 | Harnessing traction-mediated manipulation of the cell/matrix interface to control stem-cell fate | Nature Materials | 2010 | 1,349 |
| 14 | Newborn Hearing Screening — A Silent Revolution | New England Journal of Medicine | 2006 | 1,313 |
| 15 | A Novel Duodenal Iron-Regulated Transporter, IREG1, Implicated in the Basolateral Transfer of Iron to the Circulation | Molecular Cell | 2000 | 1,310 |
| 16 | Uncovering disease-disease relationships through the incomplete interactome | Science | 2015 | 1,281 |
| 17 | A Proteome-Scale Map of the Human Interactome Network | Cell | 2014 | 1,240 |
| 18 | Adhesion between epithelial cells and T lymphocytes mediated by E-cadherin and the αEβ7 integrin | Nature | 1994 | 1,136 |
| 19 | Caspase-3-Generated Fragment of Gelsolin: Effector of Morphological Change in Apoptosis | Science | 1997 | 1,122 |
| 20 | Implantation and the Survival of Early Pregnancy | New England Journal of Medicine | 2001 | 1,059 |
| 21 | Analysis of Proteins and Proteomes by Mass Spectrometry | Annual Review of Biochemistry | 2001 | 1,057 |
| 22 | The Multifaceted Functions of Neutrophils | Annual Review of Pathology: Mechanisms of Disease | 2014 | 1,009 |
| 23 | Selenoproteins: Molecular Pathways and Physiological Roles | Physiological Reviews | 2014 | 1,000 |
| 24 | Natural and synthetic non-peptide antigens recognized by human γδ T cells | Nature | 1995 | 974 |
| 25 | Recognition of a lipid antigen by CD1-restricted αβ+ T cells | Nature | 1994 | 966 |
| 26 | (-)-Epicatechin mediates beneficial effects of flavanol-rich cocoa on vascular function in humans | Proceedings of the National Academy of Sciences of the United States of America | 2006 | 937 |
| 27 | Membrane Phosphatidylserine Regulates Surface Charge and Protein Localization | Science | 2008 | 935 |
| 28 | An Antimicrobial Activity of Cytolytic T Cells Mediated by Granulysin | Science | 1998 | 915 |
| 29 | An Iron-Regulated Ferric Reductase Associated with the Absorption of Dietary Iron | Science | 2001 | 913 |
| 30 | Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets | Cancer Discovery | 2015 | 853 |
| 31 | The International Glossary on Infertility and Fertility Care, 2017†‡§ | Human Reproduction | 2017 | 845 |
| 32 | The ABCs of solute carriers: physiological, pathological and therapeutic implications of human membrane transport proteins | Pflugers Archiv European Journal of Physiology | 2004 | 833 |
| 33 | A family of mammalian Na+-dependent L-ascorbic acid transporters | Nature | 1999 | 832 |
| 34 | pH-Responsive Nanoparticles for Drug Delivery | Molecular Pharmaceutics | 2010 | 824 |
| 35 | Recent insights into the cellular biology of atherosclerosis | Journal of Cell Biology | 2015 | 823 |
| 36 | A Critical Role for Eosinophils in Allergic Airways Remodeling | Science | 2004 | 817 |
| 37 | Impact of HIV‐related stigma on treatment adherence: systematic review and meta‐synthesis | Journal of the International AIDS Society | 2013 | 810 |
| 38 | PAX8-PPAR γ 1 Fusion in Oncogene Human Thyroid Carcinoma | Science | 2000 | 801 |
| 39 | The International Glossary on Infertility and Fertility Care, 2017 | Fertility and Sterility | 2017 | 799 |
| 40 | Anti-Inflammatory Effects of Statins: Clinical Evidence and Basic Mechanisms | Nature Reviews Drug Discovery | 2005 | 780 |
| 41 | Nitric Oxide Synthase in Human and Rat Lung: Immunocytochemical and Histochemical Localization | American Journal of Respiratory Cell and Molecular Biology | 1993 | 773 |
| 42 | Frequent and Focal FGFR1 Amplification Associates with Therapeutically Tractable FGFR1 Dependency in Squamous Cell Lung Cancer | Science Translational Medicine | 2010 | 763 |
| 43 | Angiogenesis is regulated by a novel mechanism: pro- and antiangiogenic proteins are organized into separate platelet α granules and differentially released | Blood | 2008 | 757 |
| 44 | Epigenetic Epidemiology of the Developmental Origins Hypothesis | Annual Review of Nutrition | 2007 | 750 |
| 45 | Ablation of PRDM16 and Beige Adipose Causes Metabolic Dysfunction and a Subcutaneous to Visceral Fat Switch | Cell | 2014 | 748 |
| 46 | Efficient and Rapid Induction of a Chronic Myelogenous Leukemia-Like Myeloproliferative Disease in Mice Receiving P210 bcr/abl-Transduced Bone Marrow | Blood | 1998 | 705 |
| 47 | PGC-1 α, A Potential Therapeutic Target for Early Intervention in Parkinson’s Disease | Science Translational Medicine | 2010 | 705 |
| 48 | Stem cell engraftment at the endosteal niche is specified by the calcium-sensing receptor | Nature | 2006 | 669 |
| 49 | Genome Sequencing of SHH Medulloblastoma Predicts Genotype-Related Response to Smoothened Inhibition | Cancer Cell | 2014 | 648 |
| 50 | Extreme Th1 bias of invariant Vα24JαQ T cells in type 1 diabetes | Nature | 1998 | 644 |
