| # | Title | Journal | Year | Citations |
|---|
|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,158 |
| 2 | The Placenta Harbors a Unique Microbiome | Science Translational Medicine | 2014 | 1,762 |
| 3 | Cardiac progenitor cells from adult myocardium: Homing, differentiation, and fusion after infarction | Proceedings of the National Academy of Sciences of the United States of America | 2003 | 1,661 |
| 4 | The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Myeloid and Histiocytic/Dendritic Neoplasms | Leukemia | 2022 | 1,619 |
| 5 | The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms | Leukemia | 2022 | 1,398 |
| 6 | Immune evasion in cancer: Mechanistic basis and therapeutic strategies | Seminars in Cancer Biology | 2015 | 1,203 |
| 7 | Swine as Models in Biomedical Research and Toxicology Testing | Veterinary Pathology | 2012 | 1,075 |
| 8 | Essential role for Nix in autophagic maturation of erythroid cells | Nature | 2008 | 1,028 |
| 9 | Antitumor activity and long-term fate of chimeric antigen receptor–positive T cells in patients with neuroblastoma | Blood | 2011 | 1,013 |
| 10 | Human PAD4 Regulates Histone Arginine Methylation Levels via Demethylimination | Science | 2004 | 913 |
| 11 | The Role of c-Jun N-terminal Kinase (JNK) in Apoptosis Induced by Ultraviolet C and γ Radiation | Journal of Biological Chemistry | 1996 | 793 |
| 12 | Updated International Consensus Diagnostic Criteria for Eosinophilic Esophagitis: Proceedings of the AGREE Conference | Gastroenterology | 2018 | 772 |
| 13 | Effects of probiotics on gut microbiota: mechanisms of intestinal immunomodulation and neuromodulation | Therapeutic Advances in Gastroenterology | 2013 | 762 |
| 14 | Toll-Like Receptor 8-Mediated Reversal of CD4 + Regulatory T Cell Function | Science | 2005 | 717 |
| 15 | HER2-Specific Chimeric Antigen Receptor–Modified Virus-Specific T Cells for Progressive Glioblastoma | JAMA Oncology | 2017 | 655 |
| 16 | Functional consequences of developmentally regulated alternative splicing | Nature Reviews Genetics | 2011 | 642 |
| 17 | An inducible caspase 9 safety switch for T-cell therapy | Blood | 2005 | 634 |
| 18 | Identification of IL-17-producing FOXP3+regulatory T cells in humans | Proceedings of the National Academy of Sciences of the United States of America | 2009 | 634 |
| 19 | Heparanase promotes tumor infiltration and antitumor activity of CAR-redirected T lymphocytes | Nature Medicine | 2015 | 626 |
| 20 | Mutual regulation of tumour vessel normalization and immunostimulatory reprogramming | Nature | 2017 | 599 |
| 21 | Gastrointestinal Microbiome Signatures of Pediatric Patients With Irritable Bowel Syndrome | Gastroenterology | 2011 | 595 |
| 22 | Congenital cytomegalovirus infection in pregnancy and the neonate: consensus recommendations for prevention, diagnosis, and therapy | Lancet Infectious Diseases, The | 2017 | 592 |
| 23 | A Metagenomic Approach to Characterization of the Vaginal Microbiome Signature in Pregnancy | PLoS ONE | 2012 | 592 |
| 24 | IL-25 augments type 2 immune responses by enhancing the expansion and functions of TSLP-DC–activated Th2 memory cells | Journal of Experimental Medicine | 2007 | 589 |
| 25 | Closely related T-memory stem cells correlate with in vivo expansion of CAR.CD19-T cells and are preserved by IL-7 and IL-15 | Blood | 2014 | 577 |
| 26 | Transcription-linked acetylation by Gcn5p of histones H3 and H4 at specific lysines | Nature | 1996 | 569 |
| 27 | Noncoding Effects of Circular RNA CCDC66 Promote Colon Cancer Growth and Metastasis | Cancer Research | 2017 | 558 |
| 28 | Tumor-Specific Human CD4+ Regulatory T Cells and Their Ligands | Immunity | 2004 | 519 |
| 29 | Set2 Is a Nucleosomal Histone H3-Selective Methyltransferase That Mediates Transcriptional Repression | Molecular and Cellular Biology | 2002 | 504 |
| 30 | Antielastin autoimmunity in tobacco smoking–induced emphysema | Nature Medicine | 2007 | 499 |
| 31 | Engineering CD19-specific T lymphocytes with interleukin-15 and a suicide gene to enhance their anti-lymphoma/leukemia effects and safety | Leukemia | 2010 | 493 |
| 32 | Impact of Respiratory Virus Infections on Persons With Chronic Underlying Conditions | JAMA - Journal of the American Medical Association | 2000 | 483 |
| 33 | Regulation of protein-ligand binding affinity by hydrogen bond pairing | Science Advances | 2016 | 481 |
| 34 | Update on the use of immunoglobulin in human disease: A review of evidence | Journal of Allergy and Clinical Immunology | 2017 | 481 |
| 35 | Natural killer cell deficiency | Journal of Allergy and Clinical Immunology | 2013 | 480 |
| 36 | Immune mechanisms at the maternal-fetal interface: perspectives and challenges | Nature Immunology | 2015 | 478 |
| 37 | T lymphocytes coexpressing CCR4 and a chimeric antigen receptor targeting CD30 have improved homing and antitumor activity in a Hodgkin tumor model | Blood | 2009 | 470 |
| 38 | A Pan-Cancer Proteogenomic Atlas of PI3K/AKT/mTOR Pathway Alterations | Cancer Cell | 2017 | 469 |
| 39 | Early-onset lymphoproliferation and autoimmunity caused by germline STAT3 gain-of-function mutations | Blood | 2015 | 453 |
| 40 | Dynamic analyses of alternative polyadenylation from RNA-seq reveal a 3′-UTR landscape across seven tumour types | Nature Communications | 2014 | 452 |
| 41 | The Identification and Characterization of Breast Cancer CTCs Competent for Brain Metastasis | Science Translational Medicine | 2013 | 450 |
| 42 | MELAS syndrome: Clinical manifestations, pathogenesis, and treatment options | Molecular Genetics and Metabolism | 2015 | 448 |
| 43 | Human Microbiome in Health and Disease | Annual Review of Pathology: Mechanisms of Disease | 2012 | 434 |
| 44 | Persistent Activation of c-Jun N-terminal Kinase 1 (JNK1) in γ Radiation-induced Apoptosis | Journal of Biological Chemistry | 1996 | 429 |
| 45 | Effect of Erythropoietin and Transfusion Threshold on Neurological Recovery After Traumatic Brain Injury | JAMA - Journal of the American Medical Association | 2014 | 427 |
| 46 | Matrix Metalloproteinases in Lung: Multiple, Multifarious, and Multifaceted | Physiological Reviews | 2007 | 421 |
| 47 | Growth Retardation and Leaky SCID Phenotype of Ku70-Deficient Mice | Immunity | 1997 | 417 |
| 48 | Ku86-Deficient Mice Exhibit Severe Combined Immunodeficiency and Defective Processing of V(D)J Recombination Intermediates | Cell | 1996 | 416 |
| 49 | Compositional and Functional Features of the Gastrointestinal Microbiome and Their Effects on Human Health | Gastroenterology | 2014 | 416 |
| 50 | Pre-mRNA splicing in disease and therapeutics | Trends in Molecular Medicine | 2012 | 415 |
