| # | Title | Journal | Year | Citations |
|---|
|
| 1 | Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines | Journal of Extracellular Vesicles | 2018 | 7,596 |
| 2 | A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains | Nature Medicine | 2000 | 1,971 |
| 3 | Epilepsy in adults | Lancet, The | 2019 | 1,229 |
| 4 | Synaptic Assembly of the Brain in the Absence of Neurotransmitter Secretion | Science | 2000 | 1,209 |
| 5 | Analysis of shared heritability in common disorders of the brain | Science | 2018 | 1,165 |
| 6 | Coding of facial expressions of pain in the laboratory mouse | Nature Methods | 2010 | 1,089 |
| 7 | Development of the PHASES score for prediction of risk of rupture of intracranial aneurysms: a pooled analysis of six prospective cohort studies | Lancet Neurology, The | 2014 | 1,044 |
| 8 | EANO guidelines on the diagnosis and treatment of diffuse gliomas of adulthood | Nature Reviews Clinical Oncology | 2021 | 966 |
| 9 | Oral triptans (serotonin 5-HT1B/1D agonists) in acute migraine treatment: a meta-analysis of 53 trials | Lancet, The | 2001 | 936 |
| 10 | European Association for Neuro-Oncology (EANO) guideline on the diagnosis and treatment of adult astrocytic and oligodendroglial gliomas | Lancet Oncology, The | 2017 | 862 |
| 11 | Myasthenia gravis: subgroup classification and therapeutic strategies | Lancet Neurology, The | 2015 | 841 |
| 12 | Prevalence of superficial siderosis in patients with cerebral amyloid angiopathy | Neurology | 2010 | 787 |
| 13 | Glioblastoma in adults: a Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future directions | Neuro-Oncology | 2020 | 652 |
| 14 | Assessment of autonomic dysfunction in Parkinson's disease: The SCOPA‐AUT | Movement Disorders | 2004 | 635 |
| 15 | A Cacna1a Knockin Migraine Mouse Model with Increased Susceptibility to Cortical Spreading Depression | Neuron | 2004 | 602 |
| 16 | EULAR recommendations for the management of systemic lupus erythematosus with neuropsychiatric manifestations: report of a task force of the EULAR standing committee for clinical affairs | Annals of the Rheumatic Diseases | 2010 | 602 |
| 17 | Clinical features and pathophysiology of complex regional pain syndrome | Lancet Neurology, The | 2011 | 567 |
| 18 | Triptans (Serotonin, 5-HT1B/1DAgonists) in Migraine: Detailed Results and Methods of A Meta-Analysis of 53 Trials | Cephalalgia | 2002 | 563 |
| 19 | Analysis of a sleep-dependent neuronal feedback loop: the slow-wave microcontinuity of the EEG | IEEE Transactions on Biomedical Engineering | 2000 | 560 |
| 20 | The TREAT-NMD DMD Global Database: Analysis of More than 7,000 Duchenne Muscular Dystrophy Mutations | Human Mutation | 2015 | 550 |
| 21 | Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine | Nature Genetics | 2016 | 549 |
| 22 | Systematic evaluation of rating scales for impairment and disability in Parkinson's disease | Movement Disorders | 2002 | 542 |
| 23 | Screening for tumours in paraneoplastic syndromes: report of an EFNS Task Force | European Journal of Neurology | 2011 | 504 |
| 24 | Theoretic applicability of antisense-mediated exon skipping for Duchenne muscular dystrophy mutations | Human Mutation | 2009 | 499 |
| 25 | The prevalence and characteristics of migraine in a population-based cohort | Neurology | 1999 | 494 |
| 26 | A meta‐analysis of six prospective studies of falling in Parkinson's disease | Movement Disorders | 2007 | 459 |
| 27 | Low cerebrospinal fluid hypocretin (orexin) and altered energy homeostasis in human narcolepsy | Annals of Neurology | 2001 | 453 |
| 28 | Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease | Proceedings of the National Academy of Sciences of the United States of America | 2013 | 435 |
| 29 | Cardiovascular risk factors and migraine | Neurology | 2005 | 434 |
| 30 | Hypocretin (orexin) loss in Parkinson's disease | Brain | 2007 | 416 |
| 31 | Narcolepsy — clinical spectrum, aetiopathophysiology, diagnosis and treatment | Nature Reviews Neurology | 2019 | 410 |
| 32 | CSF hypocretin/orexin levels in narcolepsy and other neurological conditions | Neurology | 2001 | 402 |
| 33 | C-terminal truncations in human 3′-5′ DNA exonuclease TREX1 cause autosomal dominant retinal vasculopathy with cerebral leukodystrophy | Nature Genetics | 2007 | 384 |
| 34 | Ketamine produces effective and long-term pain relief in patients with Complex Regional Pain Syndrome Type 1 | Pain | 2009 | 382 |
| 35 | Lambert–Eaton myasthenic syndrome: from clinical characteristics to therapeutic strategies | Lancet Neurology, The | 2011 | 378 |
| 36 | Aβ is targeted to the vasculature in a mouse model of hereditary cerebral hemorrhage with amyloidosis | Nature Neuroscience | 2004 | 371 |
| 37 | Efficacy and tolerability of erenumab in patients with episodic migraine in whom two-to-four previous preventive treatments were unsuccessful: a randomised, double-blind, placebo-controlled, phase 3b study | Lancet, The | 2018 | 368 |
| 38 | Genome-wide association study reveals three susceptibility loci for common migraine in the general population | Nature Genetics | 2011 | 367 |
| 39 | De novo mutations in ATP1A3 cause alternating hemiplegia of childhood | Nature Genetics | 2012 | 353 |
| 40 | Genome-wide meta-analysis identifies new susceptibility loci for migraine | Nature Genetics | 2013 | 350 |
| 41 | Novel mutations in the Na+, K+-ATPase pump geneATP1A2 associated with familial hemiplegic migraine and benign familial infantile convulsions | Annals of Neurology | 2003 | 341 |
| 42 | Epidemiology of headache in Europe | European Journal of Neurology | 2006 | 337 |
| 43 | Migraine pathophysiology: lessons from mouse models and human genetics | Lancet Neurology, The | 2015 | 326 |
| 44 | Delayed cerebral edema and fatal coma after minor head trauma: Role of the CACNA1A calcium channel subunit gene and relationship with familial hemiplegic migraine | Annals of Neurology | 2001 | 321 |
| 45 | Narcolepsy:Clinical Features, New Pathophysiologic Insights, and Future Perspectives | Journal of Clinical Neurophysiology | 2001 | 319 |
| 46 | Loss-of-function mutations in MICU1 cause a brain and muscle disorder linked to primary alterations in mitochondrial calcium signaling | Nature Genetics | 2014 | 318 |
| 47 | Assessment of cognition in Parkinson’s disease | Neurology | 2003 | 316 |
| 48 | Migraine is associated with an increased risk of deep white matter lesions, subclinical posterior circulation infarcts and brain iron accumulation: The population-based MRI CAMERA study | Cephalalgia | 2010 | 315 |
| 49 | Pitolisant versus placebo or modafinil in patients with narcolepsy: a double-blind, randomised trial | Lancet Neurology, The | 2013 | 312 |
| 50 | Mutations in DEPDC5 cause familial focal epilepsy with variable foci | Nature Genetics | 2013 | 311 |
