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Top Articles

#TitleJournalYearCitations
1The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivityNature20126,763
2International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society International Multidisciplinary Classification of Lung AdenocarcinomaJournal of Thoracic Oncology20114,245
3EGF receptor gene mutations are common in lung cancers from “never smokers” and are associated with sensitivity of tumors to gefitinib and erlotinibProceedings of the National Academy of Sciences of the United States of America20044,131
4Tumour exosome integrins determine organotropic metastasisNature20153,886
5Genetic Basis for Clinical Response to CTLA-4 Blockade in MelanomaNew England Journal of Medicine20143,870
6The 2015 World Health Organization Classification of Lung TumorsJournal of Thoracic Oncology20153,495
7The landscape of somatic copy-number alteration across human cancersNature20103,428
8A microRNA polycistron as a potential human oncogeneNature20053,410
9Acquired Resistance of Lung Adenocarcinomas to Gefitinib or Erlotinib Is Associated with a Second Mutation in the EGFR Kinase DomainPLoS Medicine20053,046
10Tumor mutational load predicts survival after immunotherapy across multiple cancer typesNature Genetics20192,888
11Genomic analyses identify molecular subtypes of pancreatic cancerNature20162,822
12Integrative Clinical Genomics of Advanced Prostate CancerCell20152,809
13Genes that mediate breast cancer metastasis to lungNature20052,611
14Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patientsNature Medicine20172,585
15Tumour invasion and metastasis initiated by microRNA-10b in breast cancerNature20072,407
16Classification and diagnostic prediction of cancers using gene expression profiling and artificial neural networksNature Medicine20012,375
17The 2016 WHO Classification of Tumours of the Urinary System and Male Genital Organs—Part A: Renal, Penile, and Testicular TumoursEuropean Urology20162,367
18The evaluation of tumor-infiltrating lymphocytes (TILs) in breast cancer: recommendations by an International TILs Working Group 2014Annals of Oncology20152,255
19Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomasNature20072,207
20Whole genomes redefine the mutational landscape of pancreatic cancerNature20152,204
21Analysis of Tumor Specimens at the Time of Acquired Resistance to EGFR-TKI Therapy in 155 Patients with EGFR-Mutant Lung CancersClinical Cancer Research20132,144
22Efficacy and Toxicity Management of 19-28z CAR T Cell Therapy in B Cell Acute Lymphoblastic LeukemiaScience Translational Medicine20142,132
23Long-Term Follow-up of CD19 CAR Therapy in Acute Lymphoblastic LeukemiaNew England Journal of Medicine20182,070
24Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencingNature Biotechnology20131,841
25Comprehensive Molecular Characterization of Muscle-Invasive Bladder CancerCell20171,827
26CD19-Targeted T Cells Rapidly Induce Molecular Remissions in Adults with Chemotherapy-Refractory Acute Lymphoblastic LeukemiaScience Translational Medicine20131,794
27Endogenous human microRNAs that suppress breast cancer metastasisNature20081,756
28Comprehensive genomic profiles of small cell lung cancerNature20151,744
29REVEL: An Ensemble Method for Predicting the Pathogenicity of Rare Missense VariantsAmerican Journal of Human Genetics20161,743
30IDH1 mutation is sufficient to establish the glioma hypermethylator phenotypeNature20121,708
31Organoid Models of Human and Mouse Ductal Pancreatic CancerCell20151,674
32Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT)Journal of Molecular Diagnostics20151,662
33Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancerNature20121,640
34Mapping the Hallmarks of Lung Adenocarcinoma with Massively Parallel SequencingCell20121,634
35The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Myeloid and Histiocytic/Dendritic NeoplasmsLeukemia20221,619
36Chimeric Antigen Receptor TherapyNew England Journal of Medicine20181,614
37Genes that mediate breast cancer metastasis to the brainNature20091,610
38Virtual microdissection identifies distinct tumor- and stroma-specific subtypes of pancreatic ductal adenocarcinomaNature Genetics20151,588
39MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinibProceedings of the National Academy of Sciences of the United States of America20071,573
40International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy studyLancet, The20181,570
41Somatic Activation of KIT in Distinct Subtypes of MelanomaJournal of Clinical Oncology20061,505
42Introduction to The 2015 World Health Organization Classification of Tumors of the Lung, Pleura, Thymus, and HeartJournal of Thoracic Oncology20151,496
43Clinical-grade computational pathology using weakly supervised deep learning on whole slide imagesNature Medicine20191,471
44The genetic basis of early T-cell precursor acute lymphoblastic leukaemiaNature20121,462
45The 2016 WHO Classification of Tumours of the Urinary System and Male Genital Organs—Part B: Prostate and Bladder TumoursEuropean Urology20161,445
46Pten is essential for embryonic development and tumour suppressionNature Genetics19981,443
47Mutations in the Epidermal Growth Factor Receptor and in KRAS Are Predictive and Prognostic Indicators in Patients With Non–Small-Cell Lung Cancer Treated With Chemotherapy Alone and in Combination With ErlotinibJournal of Clinical Oncology20051,409
48The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Lymphoid NeoplasmsLeukemia20221,398
49Standards and Guidelines for the Interpretation and Reporting of Sequence Variants in CancerJournal of Molecular Diagnostics20171,364
50KRAS Mutations and Primary Resistance of Lung Adenocarcinomas to Gefitinib or ErlotinibPLoS Medicine20051,342