| # | Title | Journal | Year | Citations |
|---|
|
| 1 | The vasorelaxant effect of H2S as a novel endogenous gaseous KATP channel opener | EMBO Journal | 2001 | 1,731 |
| 2 | Two's company, three's a crowd: can H2S be the third endogenous gaseous transmitter? | FASEB Journal | 2002 | 1,671 |
| 3 | Long-term depression in the CNS | Nature Reviews Neuroscience | 2010 | 805 |
| 4 | Adverse Outcome Pathway (AOP) Development I: Strategies and Principles | Toxicological Sciences | 2014 | 547 |
| 5 | The Gasotransmitter Role of Hydrogen Sulfide | Antioxidants and Redox Signaling | 2003 | 460 |
| 6 | Role of glial cells in the regulation of the brain ion microenvironment | Progress in Neurobiology | 1989 | 436 |
| 7 | H2S-induced vasorelaxation and underlying cellular and molecular mechanisms | American Journal of Physiology - Heart and Circulatory Physiology | 2002 | 436 |
| 8 | Activation of KATPchannels by H2S in rat insulin-secreting cells and the underlying mechanisms | Journal of Physiology | 2005 | 433 |
| 9 | Role of astrocytes in the clearance of excess extracellular potassium | Neurochemistry International | 2000 | 401 |
| 10 | Hydrogen sulfide-induced relaxation of resistance mesenteric artery beds of rats | American Journal of Physiology - Heart and Circulatory Physiology | 2004 | 371 |
| 11 | Oxygen free radicals and hypercholesterolemic atherosclerosis: Effect of vitamin E | American Heart Journal | 1993 | 336 |
| 12 | Lipid peroxidation and activity of antioxidant enzymes in diabetic rats | Molecular and Cellular Biochemistry | 1995 | 331 |
| 13 | Norepinephrine triggers release of glial ATP to increase postsynaptic efficacy | Nature Neuroscience | 2005 | 311 |
| 14 | Pro‐apoptotic effect of endogenous H 2 S on human aorta smooth muscle cells | FASEB Journal | 2006 | 287 |
| 15 | Astrocyte control of the cerebrovasculature | Glia | 2007 | 287 |
| 16 | Hydrogen sulfide‐induced apoptosis of human aorta smooth muscle cells via the activation of mitogen‐activated protein kinases and caspase‐3 | FASEB Journal | 2004 | 268 |
| 17 | Lactate release from cultured astrocytes and neurons: A comparison | Glia | 1988 | 261 |
| 18 | Direct Stimulation of KATP Channels by Exogenous and Endogenous Hydrogen Sulfide in Vascular Smooth Muscle Cells | Molecular Pharmacology | 2005 | 260 |
| 19 | Dietary approach to attenuate oxidative stress, hypertension, and inflammation in the cardiovascular system | Proceedings of the National Academy of Sciences of the United States of America | 2004 | 259 |
| 20 | Increased Oxidative Stress in Rat Liver and Pancreas during Progression of Streptozotocin-Induced Diabetes | Clinical Science | 1998 | 257 |
| 21 | C‐Reactive Protein (CRP)‐Lowering Agents | Cardiovascular Drug Reviews | 2006 | 233 |
| 22 | Antioxidant activity of secoisolariciresinol diglucoside-derived metabolites, secoisolariciresinol, Enterodiol, and enterolactone | International Journal of Angiology | 2000 | 231 |
| 23 | Antioxidant activity of allicin, an active principle in garlic | Molecular and Cellular Biochemistry | 1995 | 222 |
| 24 | Modulation of endogenous production of H2S in rat tissues | Canadian Journal of Physiology and Pharmacology | 2003 | 211 |
| 25 | Pancreatic islet overproduction of H2S and suppressed insulin release in Zucker diabetic rats | Laboratory Investigation | 2009 | 197 |
| 26 | β2-Adrenergic Receptor Haplotypes in Mild, Moderate and Fatal/Near Fatal Asthma | American Journal of Respiratory and Critical Care Medicine | 1998 | 194 |
| 27 | Hydroxyl radical-scavenging property of secoisolariciresinol diglucoside (SDG) isolated from flax-seed | Molecular and Cellular Biochemistry | 1997 | 192 |
| 28 | Molecular Mechanism for H2S-Induced Activation of KATPChannels | Antioxidants and Redox Signaling | 2010 | 188 |
| 29 | H2S, Endoplasmic Reticulum Stress, and Apoptosis of Insulin-secreting Beta Cells | Journal of Biological Chemistry | 2007 | 176 |
| 30 | Dietary flax seed in prevention of hypercholesterolemic atherosclerosis | Atherosclerosis | 1997 | 175 |
| 31 | Protein purification and analysis: next generation Western blotting techniques | Expert Review of Proteomics | 2017 | 173 |
| 32 | Microglia processes block the spread of damage in the brain and require functional chloride channels | Glia | 2009 | 170 |
| 33 | The Different Facets of Dyslipidemia and Hypertension in Atherosclerosis | Current Atherosclerosis Reports | 2016 | 170 |
| 34 | Hypocholesterolemic and antiatherosclerotic effect of flax lignan complex isolated from flaxseed | Atherosclerosis | 2005 | 165 |
| 35 | Secoisolariciresinol diglucoside from flaxseed delays the development of type 2 diabetes in Zucker rat | Translational Research | 2001 | 156 |
| 36 | MicroRNA-27a/b regulates cellular cholesterol efflux, influx and esterification/hydrolysis in THP-1 macrophages | Atherosclerosis | 2014 | 156 |
| 37 | An Overview of Animal Models Related to Schizophrenia | Canadian Journal of Psychiatry | 2019 | 156 |
| 38 | ABCG5/ABCG8 in cholesterol excretion and atherosclerosis | Clinica Chimica Acta | 2014 | 151 |
| 39 | Flaxseed and Cardiovascular Health | Journal of Cardiovascular Pharmacology | 2009 | 150 |
| 40 | Antioxidant enzymes in hypercholesterolemia and effects of vitamin E in rabbits | Atherosclerosis | 1993 | 145 |
| 41 | Antioxidant defense system in diabetic kidney: A time course study | Life Sciences | 1997 | 141 |
| 42 | Role of Heme Oxygenase in Inflammation, Insulin-Signalling, Diabetes and Obesity | Mediators of Inflammation | 2010 | 132 |
| 43 | GABA- and glutamate-activated currents in glial cells of the mouse corpus callosum slice | Journal of Neuroscience Research | 1992 | 131 |
| 44 | Controversy surrounding the existence of discrete functional classes of astrocytes in adult gray matter | Glia | 2000 | 131 |
| 45 | Protective Effect of Hydrogen Sulfide on Balloon Injury-Induced Neointima Hyperplasia in Rat Carotid Arteries | American Journal of Pathology | 2007 | 128 |
| 46 | Neuroprotective Effects of Adenosine in Cerebral Ischemia: Window of Opportunity | Neuroscience and Biobehavioral Reviews | 1997 | 127 |
| 47 | The Characterization of [3H] Adenosine Uptake into Rat Cerebral Cortical Synaptosomes | Journal of Neurochemistry | 1980 | 126 |
| 48 | Potassium homeostasis in the ischemic brain | Glia | 2005 | 125 |
| 49 | Immunocytochemical evidence for a distinct GFAP-negative subpopulation of astrocytes in the adult rat hippocampus | Neuroscience Letters | 1998 | 124 |
| 50 | Reduction of hypercholesterolemic atherosclerosis by CDC-flaxseed with very low alpha-linolenic acid | Atherosclerosis | 1998 | 118 |
