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★★
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Articles
exaly
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Howard Hughes Medical Institute
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Department of Pharmacology
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Top Articles
Department of Pharmacology
Howard Hughes Medical Institute
2K
Articles
253.1K
Citations
9.2
avg. Impact Factor
254
h-index
Most Cited Articles of Department of Pharmacology in 2016
Title
Journal
Year
Citations
Biogenesis and function of tRNA fragments during sperm maturation and fertilization in mammals
Science
2016
699
Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens
Cell
2016
675
Activation of proto-oncogenes by disruption of chromosome neighborhoods
Science
2016
600
Phase separation of signaling molecules promotes T cell receptor signal transduction
Science
2016
568
The 3D Genome as Moderator of Chromosomal Communication
Cell
2016
558
Precision Tumor Recognition by T Cells With Combinatorial Antigen-Sensing Circuits
Cell
2016
529
A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response
Cell
2016
518
Noncoding RNA NORAD Regulates Genomic Stability by Sequestering PUMILIO Proteins
Cell
2016
496
Engineering Customized Cell Sensing and Response Behaviors Using Synthetic Notch Receptors
Cell
2016
440
A Comprehensive, CRISPR-based Functional Analysis of Essential Genes in Bacteria
Cell
2016
367
Engineering T Cells with Customized Therapeutic Response Programs Using Synthetic Notch Receptors
Cell
2016
335
Direct small-molecule inhibitors of KRAS: from structural insights to mechanism-based design
Nature Reviews Drug Discovery
2016
293
A Long Noncoding RNA lincRNA-EPS Acts as a Transcriptional Brake to Restrain Inflammation
Cell
2016
292
Dynamics of Translation of Single mRNA Molecules In Vivo
Cell
2016
275
CRISPR Interference Efficiently Induces Specific and Reversible Gene Silencing in Human iPSCs
Cell Stem Cell
2016
271
Overcoming mTOR resistance mutations with a new-generation mTOR inhibitor
Nature
2016
238
Mycobacterium tuberculosis induces the miR-33 locus to reprogram autophagy and host lipid metabolism
Nature Immunology
2016
201
FGF21 Regulates Sweet and Alcohol Preference
Cell Metabolism
2016
189
N-Myc Drives Neuroendocrine Prostate Cancer Initiated from Human Prostate Epithelial Cells
Cancer Cell
2016
189
The Structure of the Polycystic Kidney Disease Channel PKD2 in Lipid Nanodiscs
Cell
2016
157
KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference
Proceedings of the National Academy of Sciences of the United States of America
2016
150
A scalable strategy for high-throughput GFP tagging of endogenous human proteins
Proceedings of the National Academy of Sciences of the United States of America
2016
141
Nucleosome breathing and remodeling constrain CRISPR-Cas9 function
ELife
2016
133
Effects of aging on circadian patterns of gene expression in the human prefrontal cortex
Proceedings of the National Academy of Sciences of the United States of America
2016
132
Phosphoproteome Integration Reveals Patient-Specific Networks in Prostate Cancer
Cell
2016
132
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