| Genes expressed in human tumor endothelium | Science | 2000 | 1.6K |
| Role of BAX in the apoptotic response to anticancer agents | Science | 2000 | 767 |
| Zebrafish: a model system for the study of human disease | Current Opinion in Genetics and Development | 2000 | 506 |
| Identification of CDK4 as a target of c-MYC | Proceedings of the National Academy of Sciences of the United States of America | 2000 | 372 |
| Wild-type p53 transactivates the KILLER/DR5 gene through an intronic sequence-specific DNA-binding site | Oncogene | 2000 | 320 |
| Iron homeostasis: insights from genetics and animal models | Nature Reviews Genetics | 2000 | 293 |
| Conversion of diploidy to haploidy | Nature | 2000 | 230 |
| Role of the guanosine triphosphatase Rac2 in T helper 1 cell differentiation | Science | 2000 | 136 |
| Iron metabolism: iron deficiency and iron overload | Annual Review of Genomics and Human Genetics | 2000 | 121 |
| The TRAIL decoy receptor TRUNDD (DcR2, TRAIL-R4) is induced by adenovirus-p53 overexpression and can delay TRAIL-, p53-, and KILLER/DR5-dependent colon cancer apoptosis | Molecular Therapy | 2000 | 99 |
| p21(WAF1/CIP1) inhibits initiator caspase cleavage by TRAIL death receptor DR4 | Biochemical and Biophysical Research Communications | 2000 | 86 |
| Effect of recombinant human erythropoietin combined with granulocyte/ macrophage colony-stimulating factor in the treatment of patients with myelodysplastic syndrome | Blood | 2000 | 82 |
| In vivo immunological function of mast cells derived from embryonic stem cells: an approach for the rapid analysis of even embryonic lethal mutations in adult mice in vivo | Proceedings of the National Academy of Sciences of the United States of America | 2000 | 81 |
| Realizing the potential of zebrafish as a model for human disease | Physiological Genomics | 2000 | 73 |
| A downstream element in the human beta-globin promoter: evidence of extended sequence-specific transcription factor IID contacts | Proceedings of the National Academy of Sciences of the United States of America | 2000 | 66 |
| TEL/PDGFbetaR fusion protein activates STAT1 and STAT5: a common mechanism for transformation by tyrosine kinase fusion proteins | Experimental Hematology | 2000 | 52 |
| Repression of BRCA1 through a feedback loop involving p53 | Journal of Biological Chemistry | 2000 | 48 |
| Inositol polyphosphate 4-phosphatase type I regulates cell growth downstream of transcription factor GATA-1 | Proceedings of the National Academy of Sciences of the United States of America | 2000 | 43 |
| Homozygous deletion of the death receptor DR4 gene in a nasopharyngeal cancer cell line is associated with TRAIL resistance | International Journal of Oncology | 2000 | 37 |
| Intestinal iron absorption: current concepts circa 2000 | Digestive and Liver Disease | 2000 | 24 |
| Cell cycle control as a basis for cancer drug development (Review). | | 2000 | 12 |
| The gene encoding TBC1D1 with homology to the tre-2/USP6 oncogene, BUB2, and cdc16 maps to mouse chromosome 5 and human chromosome 4 | Cytogenetic and Genome Research | 2000 | 6 |
| Novel strategies for therapeutic design in molecular oncology using gene expression profiles | Current Opinion in Molecular Therapeutics | 2000 | 2 |
