Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01 | Science | 2010 | 871 |
Retroviral intasome assembly and inhibition of DNA strand transfer | Nature | 2010 | 546 |
Flexible use of nuclear import pathways by HIV-1 | Cell Host and Microbe | 2010 | 322 |
NLR family member NLRC5 is a transcriptional regulator of MHC class I genes | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 267 |
Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 262 |
Lymph node fibroblastic reticular cells directly present peripheral tissue antigen under steady-state and inflammatory conditions | Journal of Experimental Medicine | 2010 | 253 |
Hydrocarbon double-stapling remedies the proteolytic instability of a lengthy peptide therapeutic | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 250 |
Inhibition of follicular T-helper cells by CD8(+) regulatory T cells is essential for self tolerance | Nature | 2010 | 244 |
Capture of influenza by medullary dendritic cells via SIGN-R1 is essential for humoral immunity in draining lymph nodes | Nature Immunology | 2010 | 189 |
Structure-based modeling of the functional HIV-1 intasome and its inhibition | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 169 |
Topological layers in the HIV-1 gp120 inner domain regulate gp41 interaction and CD4-triggered conformational transitions | Molecular Cell | 2010 | 163 |
The structural basis for intramembrane assembly of an activating immunoreceptor complex | Nature Immunology | 2010 | 150 |
The requirement for cellular transportin 3 (TNPO3 or TRN-SR2) during infection maps to human immunodeficiency virus type 1 capsid and not integrase | Journal of Virology | 2010 | 150 |
Induction and rescue of Nod2-dependent Th1-driven granulomatous inflammation of the ileum | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 127 |
The stromal and haematopoietic antigen-presenting cells that reside in secondary lymphoid organs | Nature Reviews Immunology | 2010 | 122 |
Lens epithelium-derived growth factor fusion proteins redirect HIV-1 DNA integration | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 113 |
Structural biology of the T-cell receptor: insights into receptor assembly, ligand recognition, and initiation of signaling | Cold Spring Harbor Perspectives in Biology | 2010 | 109 |
TRIM5alpha Modulates Immunodeficiency Virus Control in Rhesus Monkeys | PLoS Pathogens | 2010 | 103 |
Lineage-specific transcriptional regulation of DICER by MITF in melanocytes | Cell | 2010 | 101 |
Cutting edge: nucleotide-binding oligomerization domain 1-dependent responses account for murine resistance against Trypanosoma cruzi infection | Journal of Immunology | 2010 | 92 |
Mature natural killer cells with phenotypic and functional alterations accumulate upon sustained stimulation with IL-15/IL-15Ralpha complexes | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 90 |
Hematopoietic stem cell defects in mice with deficiency of Fancd2 or Usp1 | Stem Cells | 2010 | 84 |
TIM-4, a receptor for phosphatidylserine, controls adaptive immunity by regulating the removal of antigen-specific T cells | Journal of Immunology | 2010 | 68 |
Enhancement of antigen-specific Treg vaccination in vivo | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 67 |
Promoting tolerance to proteolipid protein-induced experimental autoimmune encephalomyelitis through targeting dendritic cells | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 60 |