| Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01 | Science | 2010 | 871 |
| Recurrent BRAF mutations in Langerhans cell histiocytosis | Blood | 2010 | 791 |
| 53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers | Nature Structural and Molecular Biology | 2010 | 707 |
| Fatty acid synthase as a potential therapeutic target in cancer | Future Oncology | 2010 | 383 |
| Identification of the miR-106b~25 microRNA cluster as a proto-oncogenic PTEN-targeting intron that cooperates with its host gene MCM7 in transformation | Science Signaling | 2010 | 339 |
| Clinical activity of mTOR inhibition with sirolimus in malignant perivascular epithelioid cell tumors: targeting the pathogenic activation of mTORC1 in tumors | Journal of Clinical Oncology | 2010 | 297 |
| Lymph node fibroblastic reticular cells directly present peripheral tissue antigen under steady-state and inflammatory conditions | Journal of Experimental Medicine | 2010 | 253 |
| Hydrocarbon double-stapling remedies the proteolytic instability of a lengthy peptide therapeutic | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 250 |
| Lin28a transgenic mice manifest size and puberty phenotypes identified in human genetic association studies | Nature Genetics | 2010 | 241 |
| Transcriptional role of cyclin D1 in development revealed by a genetic-proteomic screen | Nature | 2010 | 217 |
| Cdk5rap2 regulates centrosome function and chromosome segregation in neuronal progenitors | Development (Cambridge) | 2010 | 197 |
| Capture of influenza by medullary dendritic cells via SIGN-R1 is essential for humoral immunity in draining lymph nodes | Nature Immunology | 2010 | 189 |
| PAX8 reliably distinguishes ovarian serous tumors from malignant mesothelioma | American Journal of Surgical Pathology | 2010 | 177 |
| Ovarian cancer pathogenesis: a model in evolution | Journal of Oncology | 2010 | 168 |
| Topological layers in the HIV-1 gp120 inner domain regulate gp41 interaction and CD4-triggered conformational transitions | Molecular Cell | 2010 | 163 |
| Primary ex vivo cultures of human fallopian tube epithelium as a model for serous ovarian carcinogenesis | Oncogene | 2010 | 156 |
| Mechanistic insights into Notch receptor signaling from structural and biochemical studies | Current Topics in Developmental Biology | 2010 | 152 |
| Met activation in non-small cell lung cancer is associated with de novo resistance to EGFR inhibitors and the development of brain metastasis | American Journal of Pathology | 2010 | 144 |
| NRAS mutations are rare in colorectal cancer | Diagnostic Molecular Pathology | 2010 | 139 |
| MYC regulation of a "poor-prognosis" metastatic cancer cell state | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 134 |
| Precision of pyrosequencing assay to measure LINE-1 methylation in colon cancer, normal colonic mucosa, and peripheral blood cells | Journal of Molecular Diagnostics | 2010 | 119 |
| Improving the yield of circulating tumour cells facilitates molecular characterisation and recognition of discordant HER2 amplification in breast cancer | British Journal of Cancer | 2010 | 118 |
| Inactivation of LEF1 in T-cell acute lymphoblastic leukemia | Blood | 2010 | 98 |
| Immunohistochemical expression of BRCA1 and lethal prostate cancer | Cancer Research | 2010 | 96 |
| Mature natural killer cells with phenotypic and functional alterations accumulate upon sustained stimulation with IL-15/IL-15Ralpha complexes | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 90 |
