Distinct brain transcriptome profiles in C9orf72-associated and sporadic ALS | Nature Neuroscience | 2015 | 235 |
Clinical Management of Catecholaminergic Polymorphic Ventricular Tachycardia: The Role of Left Cardiac Sympathetic Denervation | Circulation | 2015 | 174 |
Molecular Pathways: Targeting ATR in Cancer Therapy | Clinical Cancer Research | 2015 | 151 |
Brain Circuits Encoding Reward from Pain Relief | Trends in Neurosciences | 2015 | 121 |
Systematic identification of factors for provirus silencing in embryonic stem cells | Cell | 2015 | 117 |
Metabolomic Signatures for Drug Response Phenotypes: Pharmacometabolomics Enables Precision Medicine | Clinical Pharmacology and Therapeutics | 2015 | 115 |
Genetic purgatory and the cardiac channelopathies: Exposing the variants of uncertain/unknown significance issue | Heart Rhythm | 2015 | 112 |
Randomized withdrawal study of patients with symptomatic neurogenic orthostatic hypotension responsive to droxidopa | Hypertension | 2015 | 107 |
Emerging understanding of Bcl-2 biology: Implications for neoplastic progression and treatment | Biochimica Et Biophysica Acta - Molecular Cell Research | 2015 | 103 |
In vitro human cell line models to predict clinical response to anticancer drugs | Pharmacogenomics | 2015 | 95 |
White Matter Lipids as a Ketogenic Fuel Supply in Aging Female Brain: Implications for Alzheimer's Disease | EBioMedicine | 2015 | 92 |
PPAR-α and glucocorticoid receptor synergize to promote erythroid progenitor self-renewal | Nature | 2015 | 85 |
CALM3 mutation associated with long QT syndrome | Heart Rhythm | 2015 | 79 |
The International SSRI Pharmacogenomics Consortium (ISPC): a genome-wide association study of antidepressant treatment response | Translational Psychiatry | 2015 | 78 |
Plasma butyrylcholinesterase regulates ghrelin to control aggression | Proceedings of the National Academy of Sciences of the United States of America | 2015 | 77 |
Homozygous/Compound Heterozygous Triadin Mutations Associated With Autosomal-Recessive Long-QT Syndrome and Pediatric Sudden Cardiac Arrest: Elucidation of the Triadin Knockout Syndrome | Circulation | 2015 | 74 |
Late onset ipilimumab-induced pericarditis and pericardial effusion: a rare but life threatening complication | Case Reports in Oncological Medicine | 2015 | 72 |
Cardiac transcriptome and dilated cardiomyopathy genes in zebrafish | Circulation: Cardiovascular Genetics | 2015 | 72 |
The Efficacy of the Wee1 Inhibitor MK-1775 Combined with Temozolomide Is Limited by Heterogeneous Distribution across the Blood-Brain Barrier in Glioblastoma | Clinical Cancer Research | 2015 | 68 |
Enhanced Classification of Brugada Syndrome-Associated and Long-QT Syndrome-Associated Genetic Variants in the SCN5A-Encoded Na(v)1.5 Cardiac Sodium Channel | Circulation: Cardiovascular Genetics | 2015 | 65 |
Suppression of Somatic Expansion Delays the Onset of Pathophysiology in a Mouse Model of Huntington's Disease | PLoS Genetics | 2015 | 61 |
Novel Timothy syndrome mutation leading to increase in CACNA1C window current | Heart Rhythm | 2015 | 59 |
Parkin Regulates Mitosis and Genomic Stability through Cdc20/Cdh1 | Molecular Cell | 2015 | 56 |
Modulation of mitochondrial complex I activity averts cognitive decline in multiple animal models of familial Alzheimer's Disease | EBioMedicine | 2015 | 54 |
Identification and Functional Characterization of a Novel CACNA1C-Mediated Cardiac Disorder Characterized by Prolonged QT Intervals With Hypertrophic Cardiomyopathy, Congenital Heart Defects, and Sudden Cardiac Death | Circulation: Arrhythmia and Electrophysiology | 2015 | 54 |