| # | Title | Journal | Year | Citations |
|---|
|
| 1 | The Immune Landscape of Cancer | Immunity | 2018 | 4,015 |
| 2 | Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2017 | JAMA Oncology | 2019 | 1,824 |
| 3 | Prognostic Factors for Overall Survival in Patients With Metastatic Renal Cell Carcinoma Treated With Vascular Endothelial Growth Factor–Targeted Agents: Results From a Large, Multicenter Study | Journal of Clinical Oncology | 2009 | 1,799 |
| 4 | Guidelines for the management of hemophilia | Haemophilia | 2013 | 1,573 |
| 5 | Assessment of study quality for systematic reviews: a comparison of the Cochrane Collaboration Risk of Bias Tool and the Effective Public Health Practice Project Quality Assessment Tool: methodological research | Journal of Evaluation in Clinical Practice | 2012 | 1,156 |
| 6 | Phase III Trial of Chemoradiotherapy for Anaplastic Oligodendroglioma: Long-Term Results of RTOG 9402 | Journal of Clinical Oncology | 2013 | 998 |
| 7 | Metalloproteinases in biology and pathology of the nervous system | Nature Reviews Neuroscience | 2001 | 953 |
| 8 | Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life Years for 29 Cancer Groups From 2010 to 2019 | JAMA Oncology | 2022 | 919 |
| 9 | High levels of untreated distress and fatigue in cancer patients | British Journal of Cancer | 2004 | 807 |
| 10 | Abbreviated Course of Radiation Therapy in Older Patients With Glioblastoma Multiforme: A Prospective Randomized Clinical Trial | Journal of Clinical Oncology | 2004 | 776 |
| 11 | Apixaban versus enoxaparin for thromboprophylaxis after knee replacement (ADVANCE-2): a randomised double-blind trial | Lancet, The | 2010 | 726 |
| 12 | Reovirus Therapy of Tumors with Activated Ras Pathway | Science | 1998 | 660 |
| 13 | Sarcopenia is associated with postoperative infection and delayed recovery from colorectal cancer resection surgery | British Journal of Cancer | 2012 | 648 |
| 14 | Nivolumab plus ipilimumab versus sunitinib in first-line treatment for advanced renal cell carcinoma: extended follow-up of efficacy and safety results from a randomised, controlled, phase 3 trial | Lancet Oncology, The | 2019 | 625 |
| 15 | Matrix metalloproteinases and diseases of the CNS | Trends in Neurosciences | 1998 | 623 |
| 16 | Clinical practice guidelines on the evidence‐based use of integrative therapies during and after breast cancer treatment | Ca-A Cancer Journal for Clinicians | 2017 | 524 |
| 17 | Metalloproteinases: Mediators of Pathology and Regeneration in the CNS | Nature Reviews Neuroscience | 2005 | 508 |
| 18 | Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer | Nature Genetics | 2013 | 499 |
| 19 | Global burden and trends in premenopausal and postmenopausal breast cancer: a population-based study | The Lancet Global Health | 2020 | 466 |
| 20 | Impact of mindfulness-based stress reduction (MBSR) on sleep, mood, stress and fatigue symptoms in cancer outpatients | International Journal of Behavioral Medicine | 2005 | 457 |
| 21 | Radiotherapy and Temozolomide for Newly Diagnosed Glioblastoma: Recursive Partitioning Analysis of the EORTC 26981/22981-NCIC CE3 Phase III Randomized Trial | Journal of Clinical Oncology | 2006 | 455 |
| 22 | Pathophysiology of the brain extracellular matrix: a new target for remyelination | Nature Reviews Neuroscience | 2013 | 454 |
| 23 | Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles | Cell Reports | 2017 | 443 |
| 24 | Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas | Cancer Cell | 2018 | 431 |
| 25 | Exploring self‐compassion and empathy in the context of mindfulness‐based stress reduction (MBSR) | Stress and Health | 2010 | 424 |
| 26 | TGF-β-associated extracellular matrix genes link cancer-associated fibroblasts to immune evasion and immunotherapy failure | Nature Communications | 2018 | 422 |
| 27 | Loss of Heterozygosity for Chromosomes 1p and 16q Is an Adverse Prognostic Factor in Favorable-Histology Wilms Tumor: A Report From the National Wilms Tumor Study Group | Journal of Clinical Oncology | 2005 | 409 |
| 28 | Pro‐regenerative properties of cytokine‐activated astrocytes | Journal of Neurochemistry | 2004 | 406 |
| 29 | REAP: A two minute cell fractionation method | BMC Research Notes | 2010 | 405 |
| 30 | Tremelimumab plus Durvalumab in Unresectable Hepatocellular Carcinoma | NEJM Evidence | 2022 | 405 |
| 31 | State of the epidemiological evidence on physical activity and cancer prevention | European Journal of Cancer | 2010 | 399 |
| 32 | The report of Task Group 100 of the AAPM: Application of risk analysis methods to radiation therapy quality management | Medical Physics | 2016 | 383 |
| 33 | Phase III Trial Comparing Radical Radiotherapy With and Without Cisplatin Chemotherapy in Patients With Advanced Squamous Cell Cancer of the Cervix | Journal of Clinical Oncology | 2002 | 378 |
| 34 | Optimal Perioperative Care in Major Head and Neck Cancer Surgery With Free Flap Reconstruction | JAMA Otolaryngology - Head and Neck Surgery | 2017 | 370 |
| 35 | Effects of Nutritional Prehabilitation, With and Without Exercise, on Outcomes of Patients Who Undergo Colorectal Surgery: A Systematic Review and Meta-analysis | Gastroenterology | 2018 | 368 |
| 36 | The efficacy and safety of apixaban, an oral, direct factor Xa inhibitor, as thromboprophylaxis in patients following total knee replacement | Journal of Thrombosis and Haemostasis | 2007 | 364 |
| 37 | Benefit From Procarbazine, Lomustine, and Vincristine in Oligodendroglial Tumors Is Associated With Mutation ofIDH | Journal of Clinical Oncology | 2014 | 363 |
| 38 | Trends in Sedentary Behavior Among the US Population, 2001-2016 | JAMA - Journal of the American Medical Association | 2019 | 357 |
| 39 | Interferon beta in the treatment of multiple sclerosis | Neurology | 1998 | 345 |
| 40 | A multigene predictor of outcome in glioblastoma | Neuro-Oncology | 2010 | 343 |
| 41 | Intracerebral hemorrhage induces macrophage activation and matrix metalloproteinases | Annals of Neurology | 2003 | 336 |
| 42 | CXCR4 Is a Major Chemokine Receptor on Glioma Cells and Mediates Their Survival | Journal of Biological Chemistry | 2002 | 329 |
| 43 | Guidelines for preventing infectious complications among hematopoietic cell transplant recipients: a global perspective | Bone Marrow Transplantation | 2009 | 326 |
| 44 | The Patient Dignity Inventory: A Novel Way of Measuring Dignity-Related Distress in Palliative Care | Journal of Pain and Symptom Management | 2008 | 324 |
| 45 | The SPFH domain-containing proteins: more than lipid raft markers | Trends in Cell Biology | 2007 | 315 |
| 46 | Sympathy, empathy, and compassion: A grounded theory study of palliative care patients’ understandings, experiences, and preferences | Palliative Medicine | 2017 | 313 |
| 47 | Quality of life in brain tumor patients: the relative contributions of depression, fatigue, emotional distress, and existential issues | Journal of Neuro-Oncology | 2002 | 311 |
| 48 | The International Metastatic Renal Cell Carcinoma Database Consortium model as a prognostic tool in patients with metastatic renal cell carcinoma previously treated with first-line targeted therapy: a population-based study | Lancet Oncology, The | 2015 | 311 |
| 49 | The Immune Landscape of Cancer | Immunity | 2019 | 308 |
| 50 | Autologous Transplantation as Consolidation for Aggressive Non-Hodgkin's Lymphoma | New England Journal of Medicine | 2013 | 305 |
