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Top Articles

#TitleJournalYearCitations
1SwissTargetPrediction: updated data and new features for efficient prediction of protein targets of small moleculesNucleic Acids Research20193,731
2TGF-β and the TGF-β Family: Context-Dependent Roles in Cell and Tissue PhysiologyCold Spring Harbor Perspectives in Biology20161,084
3Tumor endothelium FasL establishes a selective immune barrier promoting tolerance in tumorsNature Medicine2014803
4Navigating metabolic pathways to enhance antitumour immunity and immunotherapyNature Reviews Clinical Oncology2019563
5Direct identification of clinically relevant neoepitopes presented on native human melanoma tissue by mass spectrometryNature Communications2016520
6T memory stem cells in health and diseaseNature Medicine2017516
7Ipilimumab-dependent cell-mediated cytotoxicity of regulatory T cells ex vivo by nonclassical monocytes in melanoma patientsProceedings of the National Academy of Sciences of the United States of America2015473
8Regulatory circuits of T cell function in cancerNature Reviews Immunology2016413
9Low-Dose Radiotherapy Reverses Tumor Immune Desertification and Resistance to Immunotherapy Open AccessCancer Discovery2022383
10Chromothripsis drives the evolution of gene amplification in cancerNature2020348
11T cell–induced CSF1 promotes melanoma resistance to PD1 blockadeScience Translational Medicine2018251
12Self-associated molecular patterns mediate cancer immune evasion by engaging Siglecs on T cellsJournal of Clinical Investigation2018238
13Macrophage-derived glutamine boosts satellite cells and muscle regenerationNature2020232
14Early Detection of Cancer: Past, Present, and FutureAmerican Society of Clinical Oncology Educational Book / ASCO American Society of Clinical Oncology Meeting2015223
15T cell differentiation in chronic infection and cancer: functional adaptation or exhaustion?Nature Reviews Immunology2014222
16Mechanisms of TGFβ-Induced Epithelial–Mesenchymal TransitionJournal of Clinical Medicine2016216
17Tumor lymphangiogenesis promotes T cell infiltration and potentiates immunotherapy in melanomaScience Translational Medicine2017194
18Metabolic Control of CD8+ T Cell Fate Decisions and Antitumor ImmunityTrends in Molecular Medicine2018190
19People also looked atFrontiers in Immunology2015179
20MTHFD2 is a metabolic checkpoint controlling effector and regulatory T cell fate and functionImmunity2022168
21Enforced PGC-1α expression promotes CD8 T cell fitness, memory formation and antitumor immunityCellular and Molecular Immunology2020165
22Transforming machine translation: a deep learning system reaches news translation quality comparable to human professionalsNature Communications2020147
23The Human Vaccines Project: A roadmap for cancer vaccine developmentScience Translational Medicine2016144
24A generic strategy for CRISPR-Cas9-mediated gene taggingNature Communications2015142
25Monoclonal antibodies against GARP/TGF-β1 complexes inhibit the immunosuppressive activity of human regulatory T cells in vivoScience Translational Medicine2015124
26Type II enteropathy-associated T-cell lymphoma features a unique genomic profile with highly recurrent SETD2 alterationsNature Communications2016123
27Enrichment and Expansion with Nanoscale Artificial Antigen Presenting Cells for Adoptive ImmunotherapyACS Nano2015118
28The cytokine-serum amyloid A-chemokine networkCytokine and Growth Factor Reviews2016118
29Molecular profiling of CD8 T cells in autochthonous melanoma identifies Maf as driver of exhaustionEMBO Journal2015105
30Tumor-associated factors are enriched in lymphatic exudate compared to plasma in metastatic melanoma patientsJournal of Experimental Medicine2019104
31Long-Term Engraftment of Primary Bone Marrow Stromal Cells Repairs Niche Damage and Improves Hematopoietic Stem Cell TransplantationCell Stem Cell2017103
32Mutational signature distribution varies with DNA replication timing and strand asymmetryGenome Biology2018102
33JUNB governs a feed-forward network of TGFβ signaling that aggravates breast cancer invasion.Nucleic Acids Research201892
34People also looked atFrontiers in Immunology201690
35Modulation of mTOR Signalling Triggers the Formation of Stem Cell-like Memory T CellsEBioMedicine201690
36People also looked atFrontiers in Immunology201787
37CDA directs metabolism of epigenetic nucleosides revealing a therapeutic window in cancerNature201584
38The non-canonical SMC protein SmcHD1 antagonises TAD formation and compartmentalisation on the inactive X chromosomeNature Communications201984
39Vaccination with LAG-3Ig (IMP321) and Peptides Induces Specific CD4 and CD8 T-Cell Responses in Metastatic Melanoma Patients—Report of a Phase I/IIa Clinical Trial FreeClinical Cancer Research201678
40The SET1 Complex Selects Actively Transcribed Target Genes via Multivalent Interaction with CpG Island ChromatinCell Reports201776
41The Transcription Factor Tcf1 Contributes to Normal NK Cell Development and Function by Limiting the Expression of GranzymesCell Reports201775
42Estimating the Contribution of Proteasomal Spliced Peptides to the HLA-I Ligandome*Molecular and Cellular Proteomics201873
43A new functional assay for the diagnosis of X-linked inhibitor of apoptosis (XIAP) deficiencyClinical and Experimental Immunology201471
44Magnetic nanoparticle-induced hyperthermia with appropriate payloads: Paul Ehrlich’s “magic (nano)bullet” for cancer theranostics?Cancer Treatment Reviews201668
45Uncoupling protein 2 reprograms the tumor microenvironment to support the anti-tumor immune cycleNature Immunology201964
46Chromosomal fragile site breakage by EBV-encoded EBNA1 at clustered repeatsNature202363
47Characterization of neutralizing antibody with prophylactic and therapeutic efficacy against SARS-CoV-2 in rhesus monkeysNature Communications202062
48Transient genomic instability drives tumorigenesis through accelerated clonal evolutionGenes and Development202161
49Autocrine Adenosine Regulates Tumor Polyfunctional CD73+CD4+ Effector T Cells Devoid of Immune Checkpoints FreeCancer Research201860
509H-Purine Scaffold Reveals Induced-Fit Pocket Plasticity of the BRD9 BromodomainJournal of Medicinal Chemistry201558