| 1 | TGF-β and the TGF-β Family: Context-Dependent Roles in Cell and Tissue Physiology | Cold Spring Harbor Perspectives in Biology | 2016 | 1,070 |
| 2 | Tumor endothelium FasL establishes a selective immune barrier promoting tolerance in tumors | Nature Medicine | 2014 | 778 |
| 3 | Navigating metabolic pathways to enhance antitumour immunity and immunotherapy | Nature Reviews Clinical Oncology | 2019 | 545 |
| 4 | T memory stem cells in health and disease | Nature Medicine | 2017 | 508 |
| 5 | Direct identification of clinically relevant neoepitopes presented on native human melanoma tissue by mass spectrometry | Nature Communications | 2016 | 505 |
| 6 | Ipilimumab-dependent cell-mediated cytotoxicity of regulatory T cells ex vivo by nonclassical monocytes in melanoma patients | Proceedings of the National Academy of Sciences of the United States of America | 2015 | 465 |
| 7 | Regulatory circuits of T cell function in cancer | Nature Reviews Immunology | 2016 | 409 |
| 8 | Low-Dose Radiotherapy Reverses Tumor Immune Desertification and Resistance to Immunotherapy | Cancer Discovery | 2022 | 366 |
| 9 | Chromothripsis drives the evolution of gene amplification in cancer | Nature | 2020 | 333 |
| 10 | T cell–induced CSF1 promotes melanoma resistance to PD1 blockade | Science Translational Medicine | 2018 | 247 |
| 11 | Self-associated molecular patterns mediate cancer immune evasion by engaging Siglecs on T cells | Journal of Clinical Investigation | 2018 | 234 |
| 12 | Macrophage-derived glutamine boosts satellite cells and muscle regeneration | Nature | 2020 | 224 |
| 13 | T cell differentiation in chronic infection and cancer: functional adaptation or exhaustion? | Nature Reviews Immunology | 2014 | 219 |
| 14 | Mechanisms of TGFβ-Induced Epithelial–Mesenchymal Transition | Journal of Clinical Medicine | 2016 | 215 |
| 15 | Tumor lymphangiogenesis promotes T cell infiltration and potentiates immunotherapy in melanoma | Science Translational Medicine | 2017 | 189 |
| 16 | Metabolic Control of CD8+ T Cell Fate Decisions and Antitumor Immunity | Trends in Molecular Medicine | 2018 | 187 |
| 17 | Inhibitory Receptors Beyond T Cell Exhaustion | Frontiers in Immunology | 2015 | 177 |
| 18 | Enforced PGC-1α expression promotes CD8 T cell fitness, memory formation and antitumor immunity | Cellular and Molecular Immunology | 2020 | 161 |
| 19 | Transforming machine translation: a deep learning system reaches news translation quality comparable to human professionals | Nature Communications | 2020 | 144 |
| 20 | A generic strategy for CRISPR-Cas9-mediated gene tagging | Nature Communications | 2015 | 141 |
| 21 | Type II enteropathy-associated T-cell lymphoma features a unique genomic profile with highly recurrent SETD2 alterations | Nature Communications | 2016 | 122 |
| 22 | Monoclonal antibodies against GARP/TGF-β1 complexes inhibit the immunosuppressive activity of human regulatory T cells in vivo | Science Translational Medicine | 2015 | 121 |
| 23 | Enrichment and Expansion with Nanoscale Artificial Antigen Presenting Cells for Adoptive Immunotherapy | ACS Nano | 2015 | 117 |
| 24 | The cytokine-serum amyloid A-chemokine network | Cytokine and Growth Factor Reviews | 2016 | 116 |
| 25 | Molecular profiling of
CD
8 T cells in autochthonous melanoma identifies
Maf
as driver of exhaustion | EMBO Journal | 2015 | 103 |
| 26 | Tumor-associated factors are enriched in lymphatic exudate compared to plasma in metastatic melanoma patients | Journal of Experimental Medicine | 2019 | 103 |
| 27 | Long-Term Engraftment of Primary Bone Marrow Stromal Cells Repairs Niche Damage and Improves Hematopoietic Stem Cell Transplantation | Cell Stem Cell | 2017 | 102 |
| 28 | Mutational signature distribution varies with DNA replication timing and strand asymmetry | Genome Biology | 2018 | 100 |
| 29 | JUNB governs a feed-forward network of TGFβ signaling that aggravates breast cancer invasion | Nucleic Acids Research | 2018 | 89 |
| 30 | Very Late Antigen-1 Marks Functional Tumor-Resident CD8 T Cells and Correlates with Survival of Melanoma Patients | Frontiers in Immunology | 2016 | 88 |
| 31 | Modulation of mTOR Signalling Triggers the Formation of Stem Cell-like Memory T Cells | EBioMedicine | 2016 | 88 |
| 32 | ATP Release from Chemotherapy-Treated Dying Leukemia Cells Elicits an Immune Suppressive Effect by Increasing Regulatory T Cells and Tolerogenic Dendritic Cells | Frontiers in Immunology | 2017 | 87 |
| 33 | CDA directs metabolism of epigenetic nucleosides revealing a therapeutic window in cancer | Nature | 2015 | 83 |
| 34 | The non-canonical SMC protein SmcHD1 antagonises TAD formation and compartmentalisation on the inactive X chromosome | Nature Communications | 2019 | 81 |
| 35 | Vaccination with LAG-3Ig (IMP321) and Peptides Induces Specific CD4 and CD8 T-Cell Responses in Metastatic Melanoma Patients—Report of a Phase I/IIa Clinical Trial | Clinical Cancer Research | 2016 | 76 |
| 36 | The SET1 Complex Selects Actively Transcribed Target Genes via Multivalent Interaction with CpG Island Chromatin | Cell Reports | 2017 | 74 |
| 37 | The Transcription Factor Tcf1 Contributes to Normal NK Cell Development and Function by Limiting the Expression of Granzymes | Cell Reports | 2017 | 74 |
| 38 | A new functional assay for the diagnosis of X-linked inhibitor of apoptosis (XIAP) deficiency | Clinical and Experimental Immunology | 2014 | 71 |
| 39 | Estimating the Contribution of Proteasomal Spliced Peptides to the HLA-I Ligandome* | Molecular and Cellular Proteomics | 2018 | 70 |
| 40 | Magnetic nanoparticle-induced hyperthermia with appropriate payloads: Paul Ehrlich’s “magic (nano)bullet” for cancer theranostics? | Cancer Treatment Reviews | 2016 | 68 |
| 41 | ‘Hotspots’ of Antigen Presentation Revealed by Human Leukocyte Antigen Ligandomics for Neoantigen Prioritization | Frontiers in Immunology | 2017 | 67 |
| 42 | Uncoupling protein 2 reprograms the tumor microenvironment to support the anti-tumor immune cycle | Nature Immunology | 2019 | 62 |
| 43 | Characterization of neutralizing antibody with prophylactic and therapeutic efficacy against SARS-CoV-2 in rhesus monkeys | Nature Communications | 2020 | 62 |
| 44 | Autocrine Adenosine Regulates Tumor Polyfunctional CD73+CD4+ Effector T Cells Devoid of Immune Checkpoints | Cancer Research | 2018 | 60 |
| 45 | Chromosomal fragile site breakage by EBV-encoded EBNA1 at clustered repeats | Nature | 2023 | 60 |
| 46 | Transient genomic instability drives tumorigenesis through accelerated clonal evolution | Genes and Development | 2021 | 59 |
| 47 | Lymphatic vessel density is associated with CD8+ T cell infiltration and immunosuppressive factors in human melanoma | OncoImmunology | 0 | 53 |
| 48 | The therapeutic promise of disrupting the PD-1/PD-L1 immune checkpoint in cancer: unleashing the CD8 T cell mediated anti-tumor activity results in significant, unprecedented clinical efficacy in various solid tumors | | 2015 | 52 |
| 49 | The Ovarian Cancer Chemokine Landscape Is Conducive to Homing of Vaccine-Primed and CD3/CD28–Costimulated T Cells Prepared for Adoptive Therapy | Clinical Cancer Research | 2015 | 52 |
| 50 | Antibodies as biomarker candidates for response and survival to checkpoint inhibitors in melanoma patients | | 2019 | 52 |