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Top Articles

#TitleJournalYearCitations
1Derivation and validation of the Systemic Lupus International Collaborating Clinics classification criteria for systemic lupus erythematosusArthritis and Rheumatism20123,826
2C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl HydroxylationCell20012,756
3The Achilles’ heel of senescent cells: from transcriptome to senolytic drugsAging Cell20151,908
4Development of Autoantibodies before the Clinical Onset of Systemic Lupus ErythematosusNew England Journal of Medicine20031,837
5Sequencing of 53,831 diverse genomes from the NHLBI TOPMed ProgramNature20211,419
6Guidelines for measuring reactive oxygen species and oxidative damage in cells and in vivoNature Metabolism20221,229
7A phase III, randomized, placebo-controlled study of belimumab, a monoclonal antibody that inhibits B lymphocyte stimulator, in patients with systemic lupus erythematosusArthritis and Rheumatism20111,218
8Fluorescence microscopyNature Methods20051,204
9Extracellular histones are major mediators of death in sepsisNature Medicine20091,188
102012 American College of Rheumatology guidelines for management of gout. Part 1: Systematic nonpharmacologic and pharmacologic therapeutic approaches to hyperuricemiaArthritis Care and Research20121,088
112016 American College of Rheumatology/European League Against Rheumatism classification criteria for primary Sjögren's syndromeAnnals of the Rheumatic Diseases20171,069
12Efficacy and safety of rituximab in moderately‐to‐severely active systemic lupus erythematosus: The randomized, double‐blind, phase ii/iii systemic lupus erythematosus evaluation of rituximab trialArthritis and Rheumatism20101,008
13Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other lociNature Genetics20081,001
14The antioxidants of human extracellular fluidsArchives of Biochemistry and Biophysics1990973
15Intestinal polyposis in mice with a dominant stable mutation of the beta -catenin geneEMBO Journal1999955
16Identification of a novel senolytic agent, navitoclax, targeting the Bcl‐2 family of anti‐apoptotic factorsAging Cell2016872
17Bacteria penetrate the normally impenetrable inner colon mucus layer in both murine colitis models and patients with ulcerative colitisGut2014787
18Estrogen receptors regulate innate immune cells and signaling pathwaysCellular Immunology2015759
19Reactive oxygen species, cell signaling, and cell injuryFree Radical Biology and Medicine2000750
20Rapid cloning of high-affinity human monoclonal antibodies against influenza virusNature2008749
21The interactions between inflammation and coagulationBritish Journal of Haematology2005748
22Direct observation of catch bonds involving cell-adhesion moleculesNature2003745
23Lowry determination of protein in the presence of Triton X-100Analytical Biochemistry1975732
24Rapid neutrophil adhesion to activated endothelium mediated by GMP-140Nature1990732
25Obesity in the mouse model of pro-opiomelanocortin deficiency responds to peripheral melanocortinNature Medicine1999726
26The Oxygen-Rich Postnatal Environment Induces Cardiomyocyte Cell-Cycle Arrest through DNA Damage ResponseCell2014716
27Extracellular histones promote thrombin generation through platelet-dependent mechanisms: involvement of platelet TLR2 and TLR4Blood2011697
28Sjögren syndromeNature Reviews Disease Primers2016685
29Anifrolumab, an Anti–Interferon‐α Receptor Monoclonal Antibody, in Moderate‐to‐Severe Systemic Lupus ErythematosusArthritis and Rheumatology2017646
30Toll-like Receptors on Hematopoietic Progenitor Cells Stimulate Innate Immune System ReplenishmentImmunity2006642
31The role of 8-hydroxyguanine in carcinogenesisCarcinogenesis1990638
32Antioxidants, Oxidative Stress, and Degenerative Neurological DisordersProceedings of the Society for Experimental Biology and Medicine1999630
33Human aspartic protease memapsin 2 cleaves the β-secretase site of β-amyloid precursor proteinProceedings of the National Academy of Sciences of the United States of America2000623
34Oxidative stress in brain agingImplications for therapeutics of neurodegenerative diseasesNeurobiology of Aging2002617
35Distinct Cytokine Patterns Identified from Multiplex Profiles of Murine DSS and TNBS-Induced ColitisInflammatory Bowel Diseases2009599
36Cloning of GMP-140, a granule membrane protein of platelets and endothelium: Sequence similarity to proteins involved in cell adhesion and inflammationCell1989596
37Meiotic Recombination in C. elegans Initiates by a Conserved Mechanism and Is Dispensable for Homologous Chromosome SynapsisCell1998594
38The Protein C PathwayChest2003592
39Hypoxia induces heart regeneration in adult miceNature2016563
40Platelets and neutrophil extracellular traps collaborate to promote intravascular coagulation during sepsis in miceBlood2017549
41A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humansNature Genetics2002548
42Autoimmune-Associated Congenital Heart Block: Demographics, Mortality, Morbidity and Recurrence Rates Obtained From a National Neonatal Lupus RegistryJournal of the American College of Cardiology1998536
43Biomarkers of Oxidative Stress Study II: Are oxidation products of lipids, proteins, and DNA markers of CCl4 poisoning?Free Radical Biology and Medicine2005536
44Loss of HIF-2α and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature miceNature Medicine2002523
452020 American College of Rheumatology Guideline for the Management of Reproductive Health in Rheumatic and Musculoskeletal DiseasesArthritis and Rheumatology2020514
46Biochemistry of the glycosyl-phosphatidylinositol membrane protein anchorsBiochemical Journal1987509
472012 American College of Rheumatology guidelines for management of gout. Part 2: Therapy and antiinflammatory prophylaxis of acute gouty arthritisArthritis Care and Research2012498
48Hydroxyl Free Radical Adduct of Deoxyguanosine: Sensitive Detection and Mechanisms of FormationFree Radical Research Communications1986496
49Evidence for a role of the integrin VLA-4 in lympho-hemopoiesis.Journal of Experimental Medicine1991491
50Optical sectioning microscopyNature Methods2005482