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Top Articles

#TitleJournalYearCitations
1Guidelines for the use and interpretation of assays for monitoring autophagyAutophagy20122,650
2Nanoparticles in Photodynamic TherapyChemical Reviews20152,598
3Landscape of somatic mutations in 560 breast cancer whole-genome sequencesNature20161,584
4Gefitinib plus best supportive care in previously treated patients with refractory advanced non-small-cell lung cancer: results from a randomised, placebo-controlled, multicentre study (Iressa Survival Evaluation in Lung Cancer)Lancet, The20051,453
5The landscape of cancer genes and mutational processes in breast cancerNature20121,196
6ESMO Clinical Practice Guideline for the diagnosis, staging and treatment of patients with metastatic breast cancerAnnals of Oncology20211,105
7Bystander CD8+ T cells are abundant and phenotypically distinct in human tumour infiltratesNature20181,028
8The Simons Genome Diversity Project: 300 genomes from 142 diverse populationsNature2016976
9Nasopharyngeal carcinomaLancet, The2016950
10NK cells for cancer immunotherapyNature Reviews Drug Discovery2020935
11Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinomaNature2011916
12Afatinib versus gefitinib as first-line treatment of patients with EGFR mutation-positive non-small-cell lung cancer (LUX-Lung 7): a phase 2B, open-label, randomised controlled trialLancet Oncology, The2016895
13First-line ceritinib versus platinum-based chemotherapy in advanced ALK -rearranged non-small-cell lung cancer (ASCEND-4): a randomised, open-label, phase 3 studyLancet, The2017873
14Nivolumab versus sorafenib in advanced hepatocellular carcinoma (CheckMate 459): a randomised, multicentre, open-label, phase 3 trialLancet Oncology, The2022867
15Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genesNature2010858
16Reference component analysis of single-cell transcriptomes elucidates cellular heterogeneity in human colorectal tumorsNature Genetics2017801
17Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)European Journal of Immunology2019765
18Whole-Genome and Epigenomic Landscapes of Etiologically Distinct Subtypes of CholangiocarcinomaCancer Discovery2017723
19Redefining Palliative Care—A New Consensus-Based DefinitionJournal of Pain and Symptom Management2020722
20Afatinib versus placebo for patients with advanced, metastatic non-small-cell lung cancer after failure of erlotinib, gefitinib, or both, and one or two lines of chemotherapy (LUX-Lung 1): a phase 2b/3 randomised trialLancet Oncology, The2012701
21Updated results from MONALEESA-2, a phase III trial of first-line ribociclib plus letrozole versus placebo plus letrozole in hormone receptor-positive, HER2-negative advanced breast cancerAnnals of Oncology2018642
22CholangiocarcinomaNature Reviews Disease Primers2021620
23Targeted Therapies for Lung Cancer Patients With Oncogenic Driver Molecular AlterationsJournal of Clinical Oncology2022600
24Revisiting the role of CD4+ T cells in cancer immunotherapy—new insights into old paradigmsCancer Gene Therapy2020591
25Isolation and retrieval of circulating tumor cells using centrifugal forcesScientific Reports2013575
26Microbiome Influences Prenatal and Adult Microglia in a Sex-Specific MannerCell2018569
27Chemotherapy and radiotherapy in nasopharyngeal carcinoma: an update of the MAC-NPC meta-analysisLancet Oncology, The2015553
28Onco-fetal Reprogramming of Endothelial Cells Drives Immunosuppressive Macrophages in Hepatocellular CarcinomaCell2020530
29Molecular landmarks of tumor hypoxia across cancer typesNature Genetics2019502
30Liquid Biopsy for Advanced NSCLC: A Consensus Statement From the International Association for the Study of Lung CancerJournal of Thoracic Oncology2021490
31Liquid Biopsy for Advanced Non-Small Cell Lung Cancer (NSCLC): A Statement Paper from the IASLCJournal of Thoracic Oncology2018478
32Cross-tissue single-cell landscape of human monocytes and macrophages in health and diseaseImmunity2021469
33A comprehensive survey of genomic alterations in gastric cancer reveals systematic patterns of molecular exclusivity and co-occurrence among distinct therapeutic targetsGut2012457
34Biological response of cancer cells to radiation treatmentFrontiers in Molecular Biosciences2014454
35Molecular correlates of clinical response and resistance to atezolizumab in combination with bevacizumab in advanced hepatocellular carcinomaNature Medicine2022454
36Global Epidemiology and Genetics of Hepatocellular CarcinomaGastroenterology2023451
37Slanted spiral microfluidics for the ultra-fast, label-free isolation of circulating tumor cellsLab on A Chip2014450
38Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genesNature Genetics2012438
39Pan-Asian adapted ESMO consensus guidelines for the management of patients with metastatic colorectal cancer: a JSMO–ESMO initiative endorsed by CSCO, KACO, MOS, SSO and TOSAnnals of Oncology2018427
40Targeting Aberrant RAS/RAF/MEK/ERK Signaling for Cancer TherapyCells2020424
41The MAPK and AMPK signalings: interplay and implication in targeted cancer therapyJournal of Hematology and Oncology2020401
42Non-small-cell lung cancerNature Reviews Disease Primers2024398
43Afatinib versus gefitinib in patients with EGFR mutation-positive advanced non-small-cell lung cancer: overall survival data from the phase IIb LUX-Lung 7 trialAnnals of Oncology2017396
44A common BIM deletion polymorphism mediates intrinsic resistance and inferior responses to tyrosine kinase inhibitors in cancerNature Medicine2012395
45Targeting the PI3K/Akt/mTOR pathway in non‐small cell lung cancer (NSCLC)Thoracic Cancer2020392
46Therapeutic targeting of p53: all mutants are equal, but some mutants are more equal than othersNature Reviews Clinical Oncology2017390
47Exome sequencing identifies distinct mutational patterns in liver fluke–related and non-infection-related bile duct cancersNature Genetics2013388
48Entrectinib in ROS1 fusion-positive non-small-cell lung cancer: integrated analysis of three phase 1–2 trialsLancet Oncology, The2020383
49Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition)European Journal of Immunology2021381
50Pembrolizumab versus investigator-choice chemotherapy for metastatic triple-negative breast cancer (KEYNOTE-119): a randomised, open-label, phase 3 trialLancet Oncology, The2021380