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#TitleJournalYearCitations
1Model-based Analysis of ChIP-Seq (MACS)Genome Biology200813,539
2Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010Lancet, The20129,286
3The biology, function, and biomedical applications of exosomesScience20209,176
4Efficacy and Safety of the mRNA-1273 SARS-CoV-2 VaccineNew England Journal of Medicine20217,955
5Antiinflammatory Therapy with Canakinumab for Atherosclerotic DiseaseNew England Journal of Medicine20177,440
6A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin LoopingCell20147,014
7Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010Lancet, The20125,746
8feature articles\(\def\hfill{\hskip 5em}\def\hfil{\hskip 3em}\def\eqno#1{\hfil {#1}}\)Acta Crystallographica Section D: Structural Biology20195,709
9Development of a dual-index sequencing strategy and curation pipeline for analyzing amplicon sequence data on the MiSeq Illumina sequencing platform.Applied and Environmental Microbiology20135,617
10Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010Lancet, The20125,598
11Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS): Scale presentation and clinimetric testing results†Movement Disorders20085,564
12Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018Cell Death and Differentiation20185,333
13Integrative analysis of 111 reference human epigenomesNature20154,484
14The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases.Cell19934,409
15The Genome Sequence of Drosophila melanogasterScience20004,283
16Genome-wide atlas of gene expression in the adult mouse brainNature20064,141
17UALCAN: A Portal for Facilitating Tumor Subgroup Gene Expression and Survival AnalysesNeoplasia20174,133
18Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)Autophagy20164,122
19Sequencing technologies — the next generationNature Reviews Genetics20094,090
20Hepatocellular Carcinoma: Epidemiology and Molecular CarcinogenesisGastroenterology20073,881
21The Somatic Genomic Landscape of GlioblastomaCell20133,781
22Parkinson’s disease: clinical features and diagnosisJournal of Neurology, Neurosurgery and Psychiatry20083,647
23Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2Nature Genetics19993,503
24Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumoursNature19923,401
25Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's diseaseNature Genetics20133,280
26The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Myeloid and Histiocytic/Dendritic NeoplasmsLeukemia20223,184
27National Sleep Foundation’s sleep time duration recommendations: methodology and results summarySleep Health20153,174
28Silver staining of proteins in polyacrylamide gelsAnalytical Biochemistry19813,139
29The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Lymphoid NeoplasmsLeukemia20223,088
30Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxinNature20003,060
31The 2011 report on dietary reference intakes for calcium and vitamin D from the Institute of Medicine: what clinicians need to know.Journal of Clinical Endocrinology and Metabolism20112,838
32Stromal Fibroblasts Present in Invasive Human Breast Carcinomas Promote Tumor Growth and Angiogenesis through Elevated SDF-1/CXCL12 SecretionCell20052,746
33Hepatocellular CarcinomaNew England Journal of Medicine20112,730
34Biological, clinical and population relevance of 95 loci for blood lipidsNature20102,726
35Global, Regional, and National Burden of Cardiovascular Diseases for 10 Causes, 1990 to 2015.Journal of the American College of Cardiology20172,723
36Bcl-2 Antiapoptotic Proteins Inhibit Beclin 1-Dependent AutophagyCell20052,700
37Genomic analyses identify molecular subtypes of pancreatic cancerNature20162,680
38Guidelines for the use and interpretation of assays for monitoring autophagyAutophagy20122,654
39Regulation of p53 stability by Mdm2Nature19972,608
40Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndromeCell19912,597
41Juicer Provides a One-Click System for Analyzing Loop-Resolution Hi-C ExperimentsCell Systems20162,553
42Clinical practice guidelines by the infectious diseases society of america for the treatment of methicillin-resistant Staphylococcus aureus infections in adults and children.Clinical Infectious Diseases20112,531
43The repertoire of mutational signatures in human cancerNature20202,514
44Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patientsNature Medicine20172,513
45Microbiota Modulate Behavioral and Physiological Abnormalities Associated with Neurodevelopmental DisordersCell20132,427
46Multi-omics of the gut microbial ecosystem in inflammatory bowel diseasesNature20192,421
47Distribution of repetitive DNA sequences in eubacteria and application to fingerprinting of bacterial genomes.Nucleic Acids Research19912,415
48EMAN2: An extensible image processing suite for electron microscopyJournal of Structural Biology20072,365
49Global Prevalence of Helicobacter pylori Infection: Systematic Review and Meta-AnalysisGastroenterology20172,360
50Oncogenic Signaling Pathways in The Cancer Genome AtlasCell20182,328