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Subarachnoid Hemorrhage After Precoital Tadalafil Use: a Case Report

  • Medicine
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Abstract

Tadalafil is one of the approved phosphodiesterase type 5 inhibitors, which are used in the treatment of erectile dysfunction. Few cases of intracerebral hemorrhage have been reported in the English literature, post-ingestion of PDE-5 inhibitor. We present a case of a previously healthy 35-year-old man, presenting for acute onset of severe headache post-ingestion of tadalafil to enhance his sexual performance. CT brain showed the presence of subarachnoid hemorrhage, and angiography eliminated the presence of vascular malformation. We believe that this is the 5th and youngest case of intracerebral hemorrhage post-tadalafil ingestion.

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No additional data are shared online. All available data were mentioned in the article.

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Abbreviations

Angio:

angiography

AVM:

arteriovenous malformation

Ca:

cancer

cGMP:

cyclic guanosine monophosphate

CT:

computed tomography

ED:

erectile dysfunction

FDA:

Food and Drug Administration

HTN:

hypertension

IC:

intracranial

INR:

international normalized ratio

M:

male

NO:

nitric oxide

N/A:

not available

PDE-5:

phosphodiesterase type 5

SH:

subarachnoid hemorrhage

References

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Authors

Contributions

Both authors were involved with the design, drafting, revision, and final approval of this case.

Corresponding author

Correspondence to Etienne El-Helou.

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Ethics approval was not required for this case report.

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Written informed consent was obtained from the patient for publication of this case report and accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal on request.

Conflict of Interest

The authors declare no competing interests.

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This article is part of the Topical Collection on Medicine

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El-Helou, E., Naccour, J. Subarachnoid Hemorrhage After Precoital Tadalafil Use: a Case Report. SN Compr. Clin. Med. 3, 1445–1448 (2021). https://doi.org/10.1007/s42399-021-00848-w

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  • DOI: https://doi.org/10.1007/s42399-021-00848-w

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