To promote effective guidance by health checkup results, this paper predict a likelihood of developing lifestyle-related diseases from health check data. In this paper, we focus on the fluctuation of hemoglobin A1c (HbA1c) value, which deeply connected with diabetes onset. Here we predict incensement of HbA1c value and examine which kind of health checkup item has important role for HbA1c fluctuation. Our experimental results show that, when we classify the subjects according to their gender and triglyceride (TG) fluctuation value, we will effectively evaluate the risk of diabetes onset for each class.